Recombinant Human PRNP Protein

Cat. No.: rp188414
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Fc tag ? Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥85%(SDS-PAGE) See COA
Accession #
P04156
Protein Tag
C-Fc
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Testing in progress
Size
Status
Price
Qty
10μg
rp188414-10μg
8
$145.90
50μg
rp188414-50μg
7
$435.90
100μg
rp188414-100μg
7
$697.90
1mg
rp188414-1mg
1
$4,599.90
Enter a quantity for the sizes you want to add.
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Why this grade

Animal Free,Carrier Free,Fc tag,PBS Only,≥85%(SDS-PAGE),See COA Animal Free,Carrier Free,Fc tag,PBS Only for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
Recombinant Human PRNP Protein
Synonyms
CD230 | ALTPRP | PRIP | PRP | PRNP | Major prion protein | ASCR | PrP27-30 | PrP33-35C
Grade
Animal Free, Carrier Free, Fc tag, PBS Only
Specifications & Purity
Animal Free, Carrier Free, Fc tag, PBS Only, ≥85%(SDS-PAGE), See COA
Biochemical and Physiological Mechanisms
Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May pl
Bioactivity
Testing in progress
Endotoxin Concentration
<1.0 EU/μg
Amino Acids
1-229 aa
Sequence
MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Accession #
Predicted molecular weight
48.6 kDa
SDS-PAGE
58.1 kDa, under reducing conditions; 122.4 & 250.0 kDa, under reducing conditions
Molecule Type
Protein
Storage and Shipping
Concentration
See COA
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Images

Recombinant Human PRNP Protein (rp188414) - SDS-PAGE
3 μg/lane of Recombinant Human PRNP Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 58.1 kDa under reducing conditions and 122.4 & 250.0 kDa under non-reducing conditions.
PRNP is also capable of forming monomer and homodimer (PubMed:11524679, PubMed:11900542, PubMed:14623188, PubMed:17468747, PubMed:19204296, PubMed:19927125, PubMed:20375014, PubMed:20564047).

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
ZJ25F0420782Certificate of AnalysisFeb 10, 2026 rp188414
ZJ25F0420783Certificate of AnalysisFeb 10, 2026 rp188414
ZJ25F0420784Certificate of AnalysisFeb 10, 2026 rp188414
ZJ25F0420785Certificate of AnalysisFeb 10, 2026 rp188414
Solution Calculators
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