Syringaldazine - ≥99% , CAS No.14414-32-5

CAS: 14414-32-5 Cat. No.: S133231 Molecular Weight: 360.36 EC Number: 238-390-1 PubChem CID: 135401234

GRADE & PURITY ≥99%

Synonyms

A808179 | S-9900 | Benzaldehyde, 4-hydroxy-3,5-dimethoxy-, [(4-hydroxy-3,5-dimethoxyphenyl)methylene]hydrazone | Benzaldehyde, 4-hydroxy-3,5-dimethoxy-, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]hydrazone | 4-[(1E)-[(E)-2-[(4-hydroxy-3,5-dimethoxyphenyl

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Syringaldazine is a reducing agent used in laccase and peroxidase activity studies.
A reducing agent used in laccase and peroxidase activity studies.

Specifications

Synonyms

A808179 | S-9900 | Benzaldehyde, 4-hydroxy-3, 5-dimethoxy-, [(4-hydroxy-3, 5-dimethoxyphenyl)methylene]hydrazone | Benzaldehyde, 4-hydroxy-3, 5-dimethoxy-, 2-[(4-hydroxy-3, 5-dimethoxyphenyl)methylene]hydrazone | 4-[(1E)-[(E)-2-[(4-hydroxy-3, 5-dimethoxyphenyl

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Clove aldehyde Azo (3, 5-dimethoxy-P-Hydroxybenzaldehyde) is a laccase-specific compound that can not be self-oxidized. It can act as a substrate for laccase and Peroxidase in the presence of Hydrogen Peroxide (H2O2) . Clove aldehydes also act as electron

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504773257
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773257
• Canonical Smiles: COC1=CC(=CC(=C1O)OC)C=NN=CC2=CC(=C(C(=C2)OC)O)OC
• IUPAC Name: 4-[(E)-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidenehydrazinylidene]methyl]-2,6-dimethoxyphenol
• InChIKey: YARKTHNUMGKMGS-LQGKIZFRSA-N
• INCHI: 1S/C18H20N2O6/c1-23-13-5-11(6-14(24-2)17(13)21)9-19-20-10-12-7-15(25-3)18(22)16(8-12)26-4/h5-10,21-22H,1-4H3/b19-9+,20-10+
• Isomeric SMILES: COC1=CC(=CC(=C1O)OC)/C=N/N=C/C2=CC(=C(C(=C2)OC)O)OC
• WGK Germany: 3
• PubChem CID: 135401234
• Molecular Weight: 360.36

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Phenols
      • Subclass Methoxyphenols

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Phenols
• Subclass: Methoxyphenols
• Intermediate Tree Nodes: Not available
• Direct Parent: Methoxyphenols
• Alternative Parents: Dimethoxybenzenes Phenoxy compounds Anisoles Alkyl aryl ethers Aldazines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Methoxyphenol - M-dimethoxybenzene - Dimethoxybenzene - Phenoxy compound - Anisole - Phenol ether - Methoxybenzene - Alkyl aryl ether - Aldazine - Azine - Monocyclic benzene moiety - Ether - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as methoxyphenols. These are compounds containing a methoxy group attached to the benzene ring of a phenol moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)

Discover Target: PIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)

Discover Target: KMT2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)

Discover Target: MBNL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

WRN Tbio Werner syndrome ATP-dependent helicase (8824 Activities)

Discover Target: WRN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TGR Thioredoxin glutathione reductase (28579 Activities)

Discover Target: TGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (partly), and DMF (c = 5%).
• Melt Point(°C): 209-210°C
• Molecular Weight: 360.400 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 360.132 Da
• Monoisotopic Mass: 360.132 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 405.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 1

References

1. Rui Wang, Yao Cheng, Yanan Xie, Jie Li, Yinliang Zhang, Zemin Fang, Wei Fang, Xuecheng Zhang, Yazhong Xiao.  (2019)  Statistical coupling analysis uncovers sites crucial for the proton transfer in laccase Lac15.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,      [PMID:31563321] [10.1016/j.bbrc.2019.09.088]

2. Kaifeng Xu, Ying Huo, Shiming Tang, Shuangyan Han, Ying Lin, Suiping Zheng.  (2024)  A novel laccase for alkaline medium temperature environments in the textile industry.  Biotechnology Journal,  19  (9): (2400383).  [PMID:39295545] [10.1002/biot.202400383]