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TBK1-IN-1 - ≥98% , CAS No.T659201
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC 50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity.
Appearance:Solid
IC50& Target:TBK1 22.4 nM (IC 50 )
In Vitro:TBK1-IN-1 (compound 7l; 0.1 and 1 μM; 2 h) inhibitsTBK1 downstream target genes cxcl10 and ifnβ expression in THP1 and RAW264.7 cells induced by poly (I:C) and lipopolysaccharide, respectively. TBK1-IN-1 (1-100 μM; 72 h) has moderate antiproliferativ
Biological Activity:TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC 50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity.
Specifications
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
| Canonical Smiles | CC(N1CCN(CC1)CC2=CC=CC(NC3=NC=C4C=CN(C4=N3)CCCNC(C5CCC5)=O)=C2)=O |
|---|---|
| Molecular Weight | 489.61 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
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