Tetrahydrouridine (aqueous solution) - ≥95%, 100mM in water , CAS No.18771-50-1

CAS: 18771-50-1 Cat. No.: T275497 Molecular Weight: 248.23 EC Number: 987-001-8 PubChem CID: 29243

GRADE & PURITY ≥95%, 100mM in water

Synonyms

1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one

Storage

Protected from light,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

Specifications

Synonyms

1-[3, 4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1, 3-diazinan-2-one

Specifications & Purity

≥95%, 100mM in water

Biochemical and Physiological Mechanisms

Competitive cytidine deaminase inhibitor (IC 50 = 152 μM). Uridine analog. Modulates antiproliferative effects. Orally active. Also available as a solid.

Storage

Protected from light, Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥95%

Names and Identifiers

• Isomeric SMILES: C1CN(C(=O)NC1O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
• PubChem CID: 29243
• Molecular Weight: 248.23

Associated Targets(Human)

CDA Tclin Cytidine deaminase (3 Activities)

Discover Target: CDA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Solubility: Supplied in water (100 mM)
• Sensitivity: air and light sensitive