1-(2-Methoxyphenyl)piperazine hydrochloride - Moligand™, ≥97% , Agonist of 5-HT 7 receptor, CAS No.5464-78-8, Agonist of 5-HT 7 receptor

CAS: 5464-78-8 Cat. No.: W136381 Molecular Weight: 228.72 EC Number: 226-762-6 PubChem CID: 9899402

GRADE & PURITY Moligand™, ≥97%

Synonyms

MFCD00012762 | 1-(2-Methoxyphenyl)piperazine hydrochloride, 97% | L-Se-methylselenocysteine | 1-(2-Methoxyphenyl)piperazine HCl | AC-19721 | HY-N2345 | NCGC00094390-01 | NCGC00094390-02 | AKOS003745112 | MLS001056761 | NCGC00015906-04 | NCGC00094390-03 |

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product Application：
1-(2-Methoxyphenyl)piperazine hydrochloride is used as reference material for forensic laboratories.

Specifications

Synonyms

MFCD00012762 | 1-(2-Methoxyphenyl)piperazine hydrochloride, 97% | L-Se-methylselenocysteine | 1-(2-Methoxyphenyl)piperazine HCl | AC-19721 | HY-N2345 | NCGC00094390-01 | NCGC00094390-02 | AKOS003745112 | MLS001056761 | NCGC00015906-04 | NCGC00094390-03 |

Specifications & Purity

Moligand™, ≥97%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

AGONIST

Mechanism of action

Agonist of 5-HT 7 receptor

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 504765061
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504765061
• Canonical Smiles: COC1=CC=CC=C1N2CCNCC2.Cl
• IUPAC Name: 1-(2-methoxyphenyl)piperazine;hydrochloride
• InChIKey: DDMVHGULHRJOEC-UHFFFAOYSA-N
• INCHI: 1S/C11H16N2O.ClH/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13;/h2-5,12H,6-9H2,1H3;1H
• Isomeric SMILES: COC1=CC=CC=C1N2CCNCC2.Cl
• WGK Germany: 3
• PubChem CID: 9899402
• Molecular Weight: 228.72

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Diazinanes
      • Subclass Piperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylpiperazines
• Alternative Parents: N-arylpiperazines Methoxyanilines Aminophenyl ethers Phenoxy compounds Methoxybenzenes Dialkylarylamines Anisoles Alkyl aryl ethers Dialkylamines Azacyclic compounds Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Phenylpiperazine - N-arylpiperazine - Aminophenyl ether - Methoxyaniline - Phenoxy compound - Anisole - Phenol ether - Methoxybenzene - Aniline or substituted anilines - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Tertiary amine - Secondary aliphatic amine - Ether - Azacycle - Secondary amine - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxygen compound - Hydrochloride - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HTR7 Tclin 5-hydroxytryptamine receptor 7 (0 Activities)

Discover Target: HTR7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in DMSO and Methanol.
• Sensitivity: Hygroscopic,Light sensitive
• Melt Point(°C): 217-219 °C
• Molecular Weight: 228.720 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 228.103 Da
• Monoisotopic Mass: 228.103 Da
• Topological Polar Surface Area: 24.500 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 169.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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