≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
740 Y-P (PDGFR 740Y-P) 740 Y-P (PDGFR 740Y-P, 740YPDGFR) is cell-permeable phosphopeptide activator of PI3K .
Targets
PI3K
In vitro
The PDGFR 740Y-P peptide stimulates a mitogenic response in muscle cells. The ability of the 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell permeable SH2 domain binding peptides. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose dependent and does not require insulin.
Cell Research(from reference)
Cell lines：NIH 3T3 cells
Concentrations：50 μg/ml
Incubation Time：2 h
| Molecular Weight | 3270.7(free basis) |
|---|
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2315268 | Certificate of Analysis | Jun 15, 2026 | Y413859 |
| I2315269 | Certificate of Analysis | Jun 15, 2026 | Y413859 |
| I2315270 | Certificate of Analysis | Jun 15, 2026 | Y413859 |
| I2315271 | Certificate of Analysis | Jun 15, 2026 | Y413859 |
| E2627493 | Certificate of Analysis | May 22, 2026 | Y413859 |
| E2627497 | Certificate of Analysis | May 22, 2026 | Y413859 |
| E2627499 | Certificate of Analysis | May 22, 2026 | Y413859 |
| E2627500 | Certificate of Analysis | May 22, 2026 | Y413859 |
| B2507116 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| I2315038 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| I2315039 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| I2315040 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| I2315267 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| J2430151 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| J2517208 | Certificate of Analysis | Sep 05, 2023 | Y413859 |
| Solubility | Solubility (25°C) In vitro Water: 1 mg/mL (0.3 mM); |
|---|---|
| Sensitivity | Moisture & Light sensitive |
| 1. Wang Dongyan, Shi Yihai, Lu Jie, Bao Wen, Wang Nan, Shen Qiuteng, Lin Zhenyu, Qian Lijuan, Zhu Chang. (2026) A Novel Insight into Chronic Pancreatitis Pathogenesis: the USP1/ITGB5 Axis-Mediated Stellate Cell Activation. INFLAMMATION, [PMID:41857463] [10.1007/s10753-025-02434-x] |
