8-Azaguanosine , CAS No.2133-80-4

CAS: 2133-80-4 Cat. No.: A1426535 PubChem CID: 135408506

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

8-Azaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc.

Specifications

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=N2)O)O)O
• IUPAC Name: 5-amino-3-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-triazolo[4,5-d]pyrimidin-7-one
• InChIKey: QOVIBFFZCVPCEI-UHFFFAOYSA-N
• INCHI: 1S/C9H12N6O5/c10-9-11-6-3(7(19)12-9)13-14-15(6)8-5(18)4(17)2(1-16)20-8/h2,4-5,8,16-18H,1H2,(H3,10,11,12,19)
• Isomeric SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=N2)O)O)O
• Alternate CAS: 2133-80-4
• PubChem CID: 135408506
• NSC Number: 46788
• MeSH Entry Terms: azaguanosine

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Glycosyl compounds
          • Level6 Glycosylamines

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Glycosyl compounds
• Direct Parent: Glycosylamines
• Alternative Parents: Pentoses Triazolopyrimidines Pyrimidones Heteroaromatic compounds Vinylogous amides Triazoles Tetrahydrofurans Secondary alcohols Lactams Azacyclic compounds Oxacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: N-glycosyl compound - Pentose monosaccharide - Triazolopyrimidine - Pyrimidone - Monosaccharide - Pyrimidine - Azole - Heteroaromatic compound - Vinylogous amide - 1,2,3-triazole - Triazole - Tetrahydrofuran - Lactam - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Alcohol - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary alcohol - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as glycosylamines. These are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y