Azido-PEG4-CH2-Boc - ≥95% , CAS No.864681-04-9

CAS: 864681-04-9 Cat. No.: A412466 Molecular Weight: 333.38
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
3,6,9,12-Tetraoxatetradecanoic acid, 14-azido-, 1,1-dimethylethyl ester
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Application
227,228,229
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100mg
A412466-100mg
1
$97.90
250mg
A412466-250mg
1
$193.90
1g
A412466-1g
1
$419.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG4-CH2-Boc is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Specifications

Synonyms
3, 6, 9, 12-Tetraoxatetradecanoic acid, 14-azido-, 1, 1-dimethylethyl ester
Specifications & Purity
≥95%
Biochemical and Physiological Mechanisms
Azido-PEG4-CH2-Boc is a cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be applied into the synthesis of PROTACs.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Canonical SmilesCC(C)(C)OC(=O)COCCOCCOCCOCCN=[N+]=[N-]
IUPAC Nametert-butyl 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetate
InChIKeySIOLYQZSIFQODW-UHFFFAOYSA-N
INCHI1S/C14H27N3O6/c1-14(2,3)23-13(18)12-22-11-10-21-9-8-20-7-6-19-5-4-16-17-15/h4-12H2,1-3H3
Isomeric SMILES CC(C)(C)OC(=O)COCCOCCOCCOCCN=[N+]=[N-]
Molecular Weight 333.38
Reaxy-Rn 24603834
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24603834&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic 1,3-dipolar compounds
ClassAllyl-type 1,3-dipolar organic compounds
SubclassAzo imides
Intermediate Tree Nodes Not available
Direct ParentAzo imides
Alternative Parents Carboxylic acid esters  Azo compounds  Monocarboxylic acids and derivatives  Dialkyl ethers  Organic salts  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  Organic cations  
Molecular FrameworkAliphatic acyclic compounds
Substituents Azo compound - Azo imide - Carboxylic acid ester - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Organonitrogen compound - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Organooxygen compound - Organic salt - Hydrocarbon derivative - Organic cation - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
C2521140Certificate of AnalysisOct 24, 2024 A412466
C2521141Certificate of AnalysisOct 24, 2024 A412466
C2521142Certificate of AnalysisOct 24, 2024 A412466
C2521143Certificate of AnalysisOct 24, 2024 A412466
C2521144Certificate of AnalysisOct 24, 2024 A412466
C2521145Certificate of AnalysisOct 24, 2024 A412466
Chemical and Physical Properties
SolubilitySolubility (25°C) In vitro Ethanol: mg/mL    
Molecular Weight333.380 g/mol
XLogP31.400
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count16
Exact Mass333.19 Da
Monoisotopic Mass333.19 Da
Topological Polar Surface Area77.600 Ų
Heavy Atom Count23
Formal Charge0
Complexity353.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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