D-myo-Inositol-2,4,5-triphosphate sodium salt - ≥98% , CAS No.D378587

CAS: D378587 Cat. No.: D378587 Molecular Weight: 486.04

GRADE & PURITY ≥98%

Synonyms

Ins(2,4,5)P3 (sodium salt) | 2,4,5-IP3 (sodium salt) | D-myo-inositol-2,4,5-tris(hydrogen phosphate), trisodium salt

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, D-myo-Inositol-2,4,5-triphosphate (sodium salt) (Ins(1,4,5)P3), more commonly referred to as IP3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate.3,4 Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(2,4,5)P3 is a metabolically stable analog of Ins(1,4,5)P3 that is commonly used to study Ca2+ signaling pathways. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3.

Specifications

Synonyms

Ins(2, 4, 5)P3 (sodium salt) | 2, 4, 5-IP3 (sodium salt) | D-myo-inositol-2, 4, 5-tris(hydrogen phosphate), trisodium salt

Specifications & Purity

≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: [C@@H]1([C@@H]([C@H]([C@@H]([C@H]([C@@H]1O[P](O[H])([O-])=O)O[H])O[P](O[H])([O-])=O)O[P](O[H])(=O)[O-])O[H])O[H].[Na+].[Na+].[Na+]
• Molecular Weight: 486.04