10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
ELOVL6-IN-2 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-2 inhibits mouse ELOVL6 activities, with an IC 50 value of 34 nM
In Vivo
ELOVL6-IN-2 (0.1~1mg/kg; p.o.; 2 hours) potently and dose-proportionally suppresses the elongation index in the liver . ?\nELOVL6-IN-2 (10mg/kg; p.o.; 2 hours) demonstrates highly liver penetrable . ?\nELOVL6-IN-2 (1mg/kg; p.o.; 2~24 hours) exhibits sustained plasma exposure . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male C57BL/6J mice Dosage: 0.1~1mg/kg Administration: P.o Result: Potently and dose-proportionally suppressed the elongation index in the liver. Animal Model: Male C57BL/6J mice Dosage: 10 mg/kg Administration: P.o Result: Demonstrated highly liver penetrable. Animal Model: Male C57BL/6J mice Dosage: 1 mg/kg Administration: P.o Result: Exhibited sustained plasma exposure.
IC50& Target:IC50: 34 nM (ELOVL6)
| Isomeric SMILES | CC1=C(C(=O)N(N1)C2=CC=C(C=C2)OC(F)(F)F)C3(C4=C(CC(CC4=O)(C)C)N(C3=O)C5=CC=CC=C5)C(F)(F)F |
|---|---|
| PubChem CID | 44139567 |
| Molecular Weight | 579.5 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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