Fludrocortisone-d5 is a labeled mineralcorticoid which can increase plasma fluid retention and volume. Structurally Fludrocortisone-d5 is identical to cortisol at every position except one hydrogen is replaced with a fluorine. Studies suggest that Fludrocortisone-d5 may sensitize vascular receptors to pressor amines. It has been observed that mineralcorticoids can increase the intracellular sodium concentration and decrease intracellular potassium. These studies suggest that Fludrocortisone-d5 alters the properties of adrenergic receptors as a result of a shift in intracellular cations.

Specifications

Specifications & Purity

Moligand™

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

Canonical Smiles	[2H]C1=C2CC[C@H]3C4CCC([C@H]4(C[C@@H](C3([C@H]2(CC(C1=O)([2H])[2H])C)F)O)C)(C(=O)C([2H])([2H])O)O
Isomeric SMILES	[2H]C1=C2CC[C@H]3C4CCC([C@]4(C[C@@H](C3([C@]2(CC(C1=O)([2H])[2H])C)F)O)C)(C(=O)C([2H])([2H])O)O
PubChem CID	46781595
Molecular Weight	385.48

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Associated Targets(Human)

NR3C2 Tclin Mineralocorticoid receptor (1 Activities)

Discover Target: NR3C2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Soluble in DMSO and Methanol
Melt Point(°C)	238-240°C (lit.)(dec.)

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