Fmoc-L-tryptophan - ≥98% , CAS No.35737-15-6

CAS: 35737-15-6 Cat. No.: F105471 Molecular Weight: 426.46 Beilstein Registry Number: 4216624 EC Number: 252-706-5
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
Fmoc-Trp-OH | AC-8601 | AKOS015924240 | (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)-propionic acid | (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-tryptophan | BDBM50043810 | (s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3-(1h-indol-3-yl)prop
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
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1g
F105471-1g
3
$9.90
5g
F105471-5g
1
$10.90
10g
F105471-10g
1
$11.90
25g
F105471-25g
2

$15.90

$23.90
Save $8.00 (33.47%)
100g
F105471-100g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$53.90

$80.90
Save $27.00 (33.37%)
500g
F105471-500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$215.90

$323.90
Save $108.00 (33.34%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Fmoc-Trp-OH | AC-8601 | AKOS015924240 | (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)-propionic acid | (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-tryptophan | BDBM50043810 | (s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3-(1h-indol-3-yl)prop
Specifications & Purity
≥98%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid504760340
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504760340
Canonical SmilesC1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)O
IUPAC Name(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)propanoic acid
InChIKeyMGHMWKZOLAAOTD-DEOSSOPVSA-N
INCHI1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m0/s1
Isomeric SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CNC5=CC=CC=C54)C(=O)O
WGK Germany 3
Molecular Weight 426.46
Beilstein 4216624
Reaxy-Rn 8090126
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8090126&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassFluorenes
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentFluorenes
Alternative Parents Indolyl carboxylic acids and derivatives  Alpha amino acids and derivatives  3-alkylindoles  Substituted pyrroles  Heteroaromatic compounds  Carbamate esters  Organic carbonic acids and derivatives  Monocarboxylic acids and derivatives  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Fluorene - Indolyl carboxylic acid derivative - Alpha-amino acid or derivatives - 3-alkylindole - Indole - Indole or derivatives - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Carbamic acid ester - Carbonic acid derivative - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Azacycle - Organoheterocyclic compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
C2625741Certificate of AnalysisMar 27, 2026 F105471
F2613036Certificate of AnalysisMar 27, 2026 F105471
D1902037Certificate of AnalysisMar 02, 2026 F105471
K2108756Certificate of AnalysisAug 12, 2025 F105471
H2522497Certificate of AnalysisJul 13, 2024 F105471
H2522498Certificate of AnalysisJul 13, 2024 F105471
H2522503Certificate of AnalysisJul 13, 2024 F105471
E2414123Certificate of AnalysisMay 17, 2024 F105471
G2402029Certificate of AnalysisMay 17, 2024 F105471
A2409028Certificate of AnalysisOct 22, 2022 F105471
J2219151Certificate of AnalysisOct 22, 2022 F105471

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Chemical and Physical Properties
Specific Rotation[α]-28.5 ° (C=1, DMF)
Melt Point(°C)184-186°C
Molecular Weight426.500 g/mol
XLogP34.100
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass426.158 Da
Monoisotopic Mass426.158 Da
Topological Polar Surface Area91.400 Ų
Heavy Atom Count32
Formal Charge0
Complexity663.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Cong Huang, Zhuang Hao, Ziran Wang, Hao Wang, Xuezeng Zhao, Yunlu Pan.  (2022)  An Ultraflexible and Transparent Graphene-Based Wearable Sensor for Biofluid Biomarkers Detection.  Advanced Materials Technologies,  (6): (2101131).  [PMID:] [10.1002/admt.202101131]
Solution Calculators
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