L-Norvaline - Moligand™, 10 mM in Water , CAS No.6600-40-4

CAS: 6600-40-4 Cat. No.: L1500999 Molecular Weight: 117.15 Beilstein Registry Number: 1721162 EC Number: 229-543-3
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in Water
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Status
Price
Qty
1ml
L1500999-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$58.90
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Why this grade

Moligand™, 10 mM in Water Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 16 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

L-Norvaline is the inhibitor for arginase , that promotes the production of NO, reduces oxidative stress, improves insulin resistance, and exhibits antioxidant and anti-hyperglycemic effects. L-Norvaline can be used in research of Alzheimer’s disease .

Specifications

Specifications & Purity
Moligand™, 10 mM in Water
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ANTAGONIST
Names and Identifiers
Isomeric SMILES CCC[C@@H](C(=O)O)N
WGK Germany 3
Molecular Weight 117.15
Beilstein 1721162
Reaxy-Rn 1721160
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721160&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Specific Rotation[α]+23.0 to +26.0 deg(C=10, 6mol/L HCl)
Melt Point(°C)>300°C
Documents & Articles
Citations of This Product
References
1. Jie Ni, Jie Wei, Yeqi Yu, Ming-Hui Fan, Wanting Liu, Kwun Nam Hui, Yan Yan, Yan Liu, Yanqiang Huang, Jie Zeng.  (2025)  Revealing the Role of Interfacial Water in pH-Dependent Hydroxylamine Electrosynthesis over Bi-Based Catalysts.  ACS Catalysis,      [PMID:] [10.1021/acscatal.5c04422]
2. Rongrong Zhu, Yan Yuan, Rourou Qi, Jianying Liang, Yan Shi, Hongbo Weng.  (2023)  Quantitative profiling of carboxylic compounds by gas chromatography-mass spectrometry for revealing biomarkers of diabetic kidney disease.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:38029665] [10.1016/j.jchromb.2023.123930]
3. Shaobo Yang, Hong Yang, Yanlei Huang, Gong Chen, Chun Shen, Shan Zheng.  (2023)  Serum Metabolomic Signatures of Hirschsprung’s Disease Based on GC–MS and LC–MS.  JOURNAL OF PROTEOME RESEARCH,      [PMID:37235583] [10.1021/acs.jproteome.3c00008]
4. Xiao-xiao Zheng, Ding-xiang Li, Ya-ting Li, Yu-lang Chen, Yan-lin Zhao, Shuai Ji, Meng-zhe Guo, Yan Du, Dao-Quan Tang.  (2023)  Mulberry leaf water extract alleviates type 2 diabetes in mice via modulating gut microbiota-host co-metabolism of branched-chain amino acid.  PHYTOTHERAPY RESEARCH,      [PMID:37013717] [10.1002/ptr.7822]
5. Kai Cai, Yongpeng Zhao, Zongjing Kang, Shuling Wang, Alan L. Wright, Xianjun Jiang.  (2022)  Environmental pseudotargeted metabolomics: A high throughput and wide coverage method for metabolic profiling of 1000-year paddy soil chronosequences.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:36343812] [10.1016/j.scitotenv.2022.159978]
6. Yaning Qin, Zhaoyue Yan, Rui Liu, Chaojie Qu, Haichen Mao, Lingbo Qu, Ran Yang.  (2021)  Ultra-sensitive detection of ATP in serum and lysates based on nitrogen-doped carbon dots.  LUMINESCENCE,  36  (7): (1584-1591).  [PMID:33900056] [10.1002/bio.4061]
7. Qu Fei, Yan Hang, Li Kexin, You Jinmao, Han Wenli.  (2020)  A covalent organic framework–MnO2 nanosheet system for determination of glutathione.  JOURNAL OF MATERIALS SCIENCE,  55  (23): (10022-10034).  [PMID:] [10.1007/s10853-020-04754-9]
8. Hao-Hua Deng, Xiao-Qiong Shi, Hua-Ping Peng, Quan-Quan Zhuang, Yu Yang, Ai-Lin Liu, Xing-Hua Xia, Wei Chen.  (2018)  Gold Nanoparticle-Based Photoluminescent Nanoswitch Controlled by Host–Guest Recognition and Enzymatic Hydrolysis for Arginase Activity Assay.  ACS Applied Materials & Interfaces,      [PMID:29373021] [10.1021/acsami.7b19513]
9. Fei Qu, Yanqun Liu, Haili Lao, Yaping Wang, Jinmao You.  (2017)  Colorimetric detection of heparin with high sensitivity based on the aggregation of gold nanoparticles induced by polymer nanoparticles.  NEW JOURNAL OF CHEMISTRY,  41  (19): (10592-10597).  [PMID:] [10.1039/C7NJ02381B]
10. Yuanhao Cai, Yulong Chen, Qijie Li, Liang Li, Haoxin Huang, Suying Wang, Weixing Wang.  (2017)  CO2 Hydrate Formation Promoted by a Natural Amino Acid l-Methionine for Possible Application to CO2 Capture and Storage.  Energy Technology,  (8): (1195-1199).  [PMID:] [10.1002/ente.201600731]
11. Donglin Jia, Lu Wang, Yudong Gao, Lina Zou, Baoxian Ye.  (2016)  Electrochemical behavior of metribuzin based on l-Norvaline modified electrode and its sensitive determination.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.jelechem.2016.01.016]
12. Yuan Jing, Wei Chen, Xuebai Qiu, Shuyue Qin, Weichang Gao, Chaochan Li, Wenxuan Quan, Kai Cai.  (2024)  Exploring Metabolic Characteristics in Different Geographical Locations and Yields of Nicotiana tabacum L. Using Gas Chromatography–Mass Spectrometry Pseudotargeted Metabolomics Combined with Chemometrics.  Metabolites,  14  (4): (176).  [PMID:38668304] [10.3390/metabo14040176]
13. Yi Chen, Xian Shu, Jia-Yi Guo, Yun Xiang, Shi-Yu Liang, Jin-Mei Lai, Jia-Yi Zhou, Li-Han Liu, Ping Wang.  (2024)  Nanodrugs mediate TAMs-related arginine metabolism interference to boost photodynamic immunotherapy.  JOURNAL OF CONTROLLED RELEASE,      [PMID:38272398] [10.1016/j.jconrel.2024.01.045]
14. Yan Du, Bing-ju Xu, Xu Deng, Xiao-wen Wu, Yin-jie Li, Shi-rui Wang, Yi-nan Wang, Shuai Ji, Meng-zhe Guo, Dong-zhi Yang, Dao-quan Tang.  (2018)  Predictive metabolic signatures for the occurrence and development of diabetic nephropathy and the intervention of Ginkgo biloba leaves extract based on gas or liquid chromatography with mass spectrometry.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:30599279] [10.1016/j.jpba.2018.12.017]
15. Jie Du, Chaoqun Li, Li Chai, Fabao Zhao, Lin Lv, Zongcheng Yang, Zhiyuan Zhao, Rong Gong, Liu Yang, Meng Wu, Meng Nie, Jihui Jia, Dongwei Kang, Chengjiang Gao, Wei Zhao, Mutian Jia.  (2026)  Asparagine sensing by TBK1 controls its phase separation to drive antiviral innate immune responses.  MOLECULAR CELL,  86  (4): (722-739).  [PMID:41653919] [10.1016/j.molcel.2026.01.010]
16. Xinyu Dong, Peng Zhou, Qiaomei Lou, Chang Li, Yu Du, Yu He.  (2026)  Optimal Compatibility of Main Effective Parts of Astragali Radix-Safflower for the Treatment of Cerebral Ischemia/Reperfusion by Pharmacokinetics-Pharmacodynamics Analysis Based on Microdialysis and Liquid Chromatography–Tandem Mass Spectrometry.  PHYTOCHEMICAL ANALYSIS,      [PMID:41708321] [10.1002/pca.70055]
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