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Glucocorticoid receptor (NR3C1)

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  1. GSK 9027
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    GSK 9027
    CAS: 1229096-88-1 Formula: C27H19F4N3O2S Molecular Weight: 525.52
    ≥98%(HPLC)
    In Stock Item #: G288349
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    Technical Identifiers
    IUPAC Name
    N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]-1-phenylmethanesulfonamide
    SMILES
    C1=CC=C(C=C1)CS(=O)(=O)NC2=CC(=C(C=C2)C3=CC4=C(C=C3)N(N=C4)C5=CC=C(C=C5)F)C(F)(F)F
    InChIKey
    DXBJGDVBQPEMOB-UHFFFAOYSA-N
    InChI
    1S/C27H19F4N3O2S/c28-21-7-10-23(11-8-21)34-26-13-6-19(14-20(26)16-32-34)24-12-9-22(15-25(24)27(29,30)31)33-37(35,36)17-18-4-2-1-3-5-18/h1-16,33H,17H2
    Synonyms
    N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
  2. Mestranol, Estrogen receptor alpha agonist
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    Mestranol, Estrogen receptor alpha agonist
    CAS: 72-33-3 EC Number: 200-777-8 Formula: C21H26O2 Molecular Weight: 310.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: M129878
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    Technical Identifiers
    IUPAC Name
    (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
    SMILES
    CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OC
    InChIKey
    IMSSROKUHAOUJS-MJCUULBUSA-N
    InChI
    1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,20+,21+/m1/s1
    Synonyms
    NSC 84032 | 17-alpha-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17-beta-ol | MESTRANOL [WHO-DD] | AI3-51798 | Inostral | ...
  3. Dienestrol, Estrogen receptor alpha agonist
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    Dienestrol, Estrogen receptor alpha agonist
    CAS: 84-17-3 EC Number: 201-519-7 Formula: C18H18O2 Molecular Weight: 266.33
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    In Stock Item #: D100892
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    Technical Identifiers
    IUPAC Name
    4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol
    SMILES
    CC=C(C1=CC=C(C=C1)O)C(=CC)C2=CC=C(C=C2)O
    InChIKey
    NFDFQCUYFHCNBW-SCGPFSFSSA-N
    InChI
    1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3+,18-4+
    Synonyms
    (E,E)-4,4'-(Diethylideneethylene)diphenol | Dehydrostilbestrol | Dienestrolum (INN-Latin) | Dinovex | Phenol, 4,4'-(d...
  4. Z-Guggulsterone - ≥98% CAS No(39025-23-5) by Aladdin Scientific
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    Z-Guggulsterone
    CAS: 39025-23-5 EC Number: 609-604-4 Formula: C21H28O2 Molecular Weight: 312.45
    ≥98%
    In Stock Item #: Z136302
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    Technical Identifiers
    IUPAC Name
    (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
    SMILES
    CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
    InChIKey
    WDXRGPWQVHZTQJ-OSJVMJFVSA-N
    InChI
    1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
    Synonyms
    AVQFHKYAVVQYQO-UHFFFAOYSA- | 6CST3U34GN | GUGGULSTERONE Z [USP-RS] | NCGC00260067-01 | Z/E-Guggulsterone | AC-28813 |...
  5. Norethindrone, Progesterone receptor agonist
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    Norethindrone, Progesterone receptor agonist
    CAS: 68-22-4 EC Number: 200-681-6 Formula: C20H26O2 Molecular Weight: 298.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N129448
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    Technical Identifiers
    IUPAC Name
    (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
    SMILES
    CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
    InChIKey
    VIKNJXKGJWUCNN-XGXHKTLJSA-N
    InChI
    1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1
    Synonyms
    SC 4640 | Brevinor-1 28 | Estrinor | Nodiol | Norcolut | Norethynodron | Norethynodrone | Triella | BRN 1915671 | Nor...
  6. Nilvadipine
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    Nilvadipine
    CAS: 75530-68-6 EC Number: 805-887-5 Formula: C19H19N3O6 Molecular Weight: 385.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: N129505
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    IUPAC Name
    3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES
    CC1=C(C(C(=C(N1)C#N)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C
    InChIKey
    FAIIFDPAEUKBEP-UHFFFAOYSA-N
    InChI
    1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3
    Synonyms
    CAS-75530-68-6 | CL 287,389 | NCGC00167435-02 | NCGC00167435-01 | 5-Isopropyl 3-Methyl 2-Cyano-1,4-dihydro-6-methyl-4...
  7. Nomegestrol acetate, Progesterone receptor agonist
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    Nomegestrol acetate, Progesterone receptor agonist
    CAS: 58652-20-3 EC Number: 261-379-8 Formula: C23H30O4 Molecular Weight: 370.48
    ≥98%
    In Stock Item #: N304068
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    Technical Identifiers
    IUPAC Name
    [(8S,9S,10R,13S,14S,17R)-17-acetyl-6,13-dimethyl-3-oxo-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
    SMILES
    CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4C1=CC(=O)CC4
    InChIKey
    IIVBFTNIGYRNQY-YQLZSBIMSA-N
    InChI
    1S/C23H30O4/c1-13-11-20-18(17-6-5-16(26)12-19(13)17)7-9-22(4)21(20)8-10-23(22,14(2)24)27-15(3)25/h11-12,17-18,20-21H,5-10H2,1-4H3/t17-,18-,20-,21+,22+show more
    Synonyms
    AKOS015896563 | Nomegestrone acetate | NCGC00179247-01 | (2R)-2-amino-3-[4-(trifluoromethyl)phenyl]propanoic acid | (...
  8. Gliquidone
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    Gliquidone
    CAS: 33342-05-1 EC Number: 251-463-2 Formula: C27H33N3O6S Molecular Weight: 527.63
    ≥98%
    In Stock Item #: G129565
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    Technical Identifiers
    IUPAC Name
    1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
    SMILES
    CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C
    InChIKey
    LLJFMFZYVVLQKT-UHFFFAOYSA-N
    InChI
    1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19H,4-8,15-show more
    Synonyms
    3-FORMYLTHIOPHEN-2-YL-2-BORONIC ACID | BRD-K80396088-001-03-9 | AC-23356 | Boronic acid, B-(4-methoxy-2-methylphenyl)...
  9. Betamethasone 17-valerate, Glucocorticoid receptor agonist
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    Betamethasone 17-valerate, Glucocorticoid receptor agonist
    CAS: 2152-44-5 EC Number: 218-439-3 Formula: C27H37FO6 Molecular Weight: 476.58
    ≥98%
    In Stock Item #: B123298
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    Technical Identifiers
    IUPAC Name
    [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthshow more
    SMILES
    CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO
    InChIKey
    SNHRLVCMMWUAJD-SUYDQAKGSA-N
    InChI
    1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,1show more
    Synonyms
    Fuciderm | Topagen (Veterinary) | betamethasone-valerate | Bettamousse | 9-Fluoro-11-beta,17,21-trihydroxy-16-beta-me...
  10. Medroxyprogesterone acetate - Moligand™, ≥98% CAS No(71-58-9) by Aladdin Scientific
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    Medroxyprogesterone acetate, Progesterone receptor agonist
    CAS: 71-58-9 EC Number: 200-757-9 Formula: C24H34O4 Molecular Weight: 386.52
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M129409
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    Technical Identifiers
    IUPAC Name
    [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
    SMILES
    CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
    InChIKey
    PSGAAPLEWMOORI-PEINSRQWSA-N
    InChI
    1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23show more
    Synonyms
    Clinovir | DP150 | Medroxyprogesterone acetate (Standard) | Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6alpha...
  11. Guggulsterone（pregna-4,17-diene-3,16-dione）, Antagonist of Farnesoid X receptor
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    Guggulsterone（pregna-4,17-diene-3,16-dione）, Antagonist of Farnesoid X receptor
    CAS: 95975-55-6 EC Number: 982-588-7 Formula: C21H28O2 Molecular Weight: 312.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G276180
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    Technical Identifiers
    IUPAC Name
    (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
    SMILES
    CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
    InChIKey
    WDXRGPWQVHZTQJ-OSJVMJFVSA-N
    InChI
    1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
    Synonyms
    AVQFHKYAVVQYQO-UHFFFAOYSA- | 6CST3U34GN | GUGGULSTERONE Z [USP-RS] | NCGC00260067-01 | Z/E-Guggulsterone | AC-28813 |...
  12. Chlormadinone Acetate, Progesterone receptor modulator
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    Chlormadinone Acetate, Progesterone receptor modulator
    CAS: 302-22-7 EC Number: 206-118-0 Formula: C23H29ClO4 Molecular Weight: 404.93
    ≥97%(HPLC)
    In Stock Item #: C153375
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
    SMILES
    CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)CCC34C)Cl)C)OC(=O)C
    InChIKey
    QMBJSIBWORFWQT-DFXBJWIESA-N
    InChI
    1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11-12,16-18H,5-10H2,1-4H3/t16-,17+,18+,21-,22+,show more
    Synonyms
    6-Chloro-delta(sup 6)-17-acetoxyprogesterone | Chloramdinone acetate | 6-Chloro-3,20-dioxopregna-4,6-dien-17-yl aceta...
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