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Interferon-induced, double-stranded rna-activated protein kinase (EIF2AK2)

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  1. GSK-3 Inhibitor XIII, Inhibitor of aurora kinase A;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinase
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    GSK-3 Inhibitor XIII, Inhibitor of aurora kinase A;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinase
    CAS: 404828-08-6 Formula: C18H19N5 Molecular Weight: 305.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: G338805
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    Synonyms
    (5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
  2. GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
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    GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
    CAS: 1337532-29-2 Formula: C23H21FN6O Molecular Weight: 416.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G276179
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    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    SMILES
    CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
    InChIKey
    PRWSIEBRGXYXAJ-UHFFFAOYSA-N
    InChI
    1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,2show more
    Synonyms
    1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
  3. NU 6140, Inhibitor of aurora kinase A;Inhibitor of aurora kinase B;Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 5;Inhibitor of cyclin dependent kinase 7;In
    Wish List Compare
    NU 6140, Inhibitor of aurora kinase A;Inhibitor of aurora kinase B;Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 5;Inhibitor of cyclin dependent kinase 7;In
    CAS: 444723-13-1 Formula: C23H30N6O2 Molecular Weight: 422.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N275662
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    4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide
    SMILES
    CCN(CC)C(=O)C1=CC=C(C=C1)NC2=NC3=C(C(=N2)OCC4CCCCC4)NC=N3
    InChIKey
    XHEQSRJCJTWWAH-UHFFFAOYSA-N
    InChI
    1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,show more
    Synonyms
    4-{[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino}-N,N-diethylbenzamide | E73484 | SCHEMBL2169233 | NU6140, >=98% (HPLC) ...
  4. Indirubin-3′-oxime, Inhibitor of glycogen synthase kinase 3 beta
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    Indirubin-3′-oxime, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 160807-49-8 Formula: C16H11N3O2 Molecular Weight: 277.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: I132661
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    IUPAC Name
    3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol
    SMILES
    C1=CC=C2C(=C1)C(=C(N2)O)C3=C(C4=CC=CC=C4N3)N=O
    InChIKey
    FQCPPVRJPILDIK-UHFFFAOYSA-N
    InChI
    1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17-18,20H
    Synonyms
    BSPBio_001108 | UNII-X6CSG51MBQ | BDBM54681 | BCBcMAP01_000150 | HBDSHCUSXQATPO-BGBJRWHRSA-N | Indirubin 3'-monoxime ...
  5. TC-S 7006, Inhibitor of mitogen-activated protein kinase kinase kinase 8
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    TC-S 7006, Inhibitor of mitogen-activated protein kinase kinase kinase 8
    CAS: 871307-18-5 EC Number: 111-094-9 PubChem CID: 9549300 Formula: C21H14ClFN6 Molecular Weight: 404.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: T287927
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    4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile
    SMILES
    C1=CC(=CN=C1)CNC2=NC=C3C(=C2)C(=C(C=N3)C#N)NC4=CC(=C(C=C4)F)Cl
    InChIKey
    NMEUKWOOQOHUNA-UHFFFAOYSA-N
    InChI
    1S/C21H14ClFN6/c22-17-6-15(3-4-18(17)23)29-21-14(8-24)11-26-19-12-28-20(7-16(19)21)27-10-13-2-1-5-25-9-13/h1-7,9,11-12H,10H2,(H,26,29)(H,27,28)
    Synonyms
    DTXSID20946032 | 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 4-(3...
  6. STO609, Inhibitor of calcium/calmodulin dependent protein kinase kinase 1;Inhibitor of calcium/calmodulin dependent protein kinase kinase 2
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    STO609, Inhibitor of calcium/calmodulin dependent protein kinase kinase 1;Inhibitor of calcium/calmodulin dependent protein kinase kinase 2
    CAS: 52029-86-4 PubChem CID: 3467590 Formula: C19H10N2O3 Molecular Weight: 314.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: S395991
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    IUPAC Name
    11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid
    SMILES
    C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
    InChIKey
    MYKOWOGZBMOVBJ-UHFFFAOYSA-N
    InChI
    1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24)
    Synonyms
    11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid | 7H-...
  7. TPCA-1, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit beta
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    TPCA-1, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit beta
    CAS: 507475-17-4 EC Number: 637-136-0 PubChem CID: 9903786 Formula: C12H10FN3O2S Molecular Weight: 279.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T126861
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    2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
    SMILES
    C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F
    InChIKey
    SAYGKHKXGCPTLX-UHFFFAOYSA-N
    InChI
    1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
    Synonyms
    SMR001834876 | 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid | BCP05956 | Pinitol TMS | SW218246-2...
  8. TWS119, Inhibitor of glycogen synthase kinase 3 beta
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    TWS119, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 601514-19-6 EC Number: 637-358-8 PubChem CID: 9549289 Formula: C18H14N4O2 Molecular Weight: 318.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: T126075
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    IUPAC Name
    3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol
    SMILES
    C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
    InChIKey
    VPVLEBIVXZSOMQ-UHFFFAOYSA-N
    InChI
    1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
    Synonyms
    GTPL5980 | EX-A151 | K00245 | BCPP000029 | GSK-3beta Inhibitor XII, TWS119 - CAS 601514-19-6 | SCHEMBL5559045 | CHEBI...
  9. Cdk1/5 Inhibitor inhibitor, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 5;Inhibitor of glycogen synthase kinase 3 beta
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    Cdk1/5 Inhibitor inhibitor, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 5;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 40254-90-8 Formula: C9H7N5 Molecular Weight: 185.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    Out of Stock Item #: C336172
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    IUPAC Name
    2H-pyrazolo[4,3-b]quinoxalin-3-amine
    SMILES
    C1=CC2=NC3=C(NN=C3N=C2C=C1)N
    InChIKey
    DWHVZCLBMTZRQM-UHFFFAOYSA-N
    InChI
    1S/C9H7N5/c10-8-7-9(14-13-8)12-6-4-2-1-3-5(6)11-7/h1-4H,(H3,10,12,13,14)
    Synonyms
    GTPL5947 | quinoxaline 1 | HSCI1_000152 | 2H-pyrazolo[4,3-b]quinoxalin-3-amine | BRD-K87932577-001-01-6 | CHEBI:92540...
  10. GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
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    GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
    CAS: 1337532-29-2 Formula: C23H21FN6O Molecular Weight: 416.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G421276
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    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    SMILES
    CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
    InChIKey
    PRWSIEBRGXYXAJ-UHFFFAOYSA-N
    InChI
    1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,2show more
    Synonyms
    1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
  11. Indirubin-3′-oxime, Inhibitor of glycogen synthase kinase 3 beta
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    Indirubin-3′-oxime, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 160807-49-8 Formula: C16H11N3O2 Molecular Weight: 277.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: I421929
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    IUPAC Name
    3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol
    SMILES
    C1=CC=C2C(=C1)C(=C(N2)O)C3=C(C4=CC=CC=C4N3)N=O
    InChIKey
    FQCPPVRJPILDIK-UHFFFAOYSA-N
    InChI
    1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17-18,20H
    Synonyms
    BSPBio_001108 | UNII-X6CSG51MBQ | BDBM54681 | BCBcMAP01_000150 | HBDSHCUSXQATPO-BGBJRWHRSA-N | Indirubin 3'-monoxime ...
  12. JNK Inhibitor II, negative control
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    JNK Inhibitor II, negative control
    CAS: 54642-23-8 Formula: C15H10N2O Molecular Weight: 234.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: J339033
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    IUPAC Name
    14-methyl-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one
    SMILES
    CN1C2=CC=CC3=C2C(=N1)C4=CC=CC=C4C3=O
    InChIKey
    ODZGYELAMAOARP-UHFFFAOYSA-N
    InChI
    1S/C15H10N2O/c1-17-12-8-4-7-11-13(12)14(16-17)9-5-2-3-6-10(9)15(11)18/h2-8H,1H3
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