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Mast/stem cell growth factor receptor kit (KIT)

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  1. SR 3576 - ≥98% CAS No(1164153-22-3) by Aladdin Scientific
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    SR 3576
    CAS: 1164153-22-3 PubChem CID: 70702008 Formula: C27H27N5O5 Molecular Weight: 501.54
    ≥98%
    In Stock Item #: S275279
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    IUPAC Name
    3-[4-[(3-methylphenyl)carbamoylamino]pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide
    SMILES
    CC1=CC(=CC=C1)NC(=O)NC2=CN(N=C2)C3=CC=CC(=C3)C(=O)NC4=CC(=C(C(=C4)OC)OC)OC
    InChIKey
    MTFAYLZZDJGFGV-UHFFFAOYSA-N
    InChI
    1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33show more
    Synonyms
    3-[4-[(3-methylphenyl)carbamoylamino]pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide | 3-(4-(3-m-tolylureido)-1H-py...
  2. GSK2606414 - Moligand™, ≥98% CAS No(1337531-36-8) by Aladdin Scientific
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    GSK2606414
    CAS: 1337531-36-8 Formula: C24H20F3N5O Molecular Weight: 451.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G125654
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    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
    SMILES
    CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
    InChIKey
    SIXVRXARNAVBTC-UHFFFAOYSA-N
    InChI
    1S/C24H20F3N5O/c1-31-12-18(21-22(28)29-13-30-23(21)31)15-5-6-19-16(11-15)7-8-32(19)20(33)10-14-3-2-4-17(9-14)24(25,26)27/h2-6,9,11-13H,7-8,10H2,1H3,(Hshow more
    Synonyms
    AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
  3. R406 (free base), Tyrosine-protein kinase SYK inhibitor
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    R406 (free base), Tyrosine-protein kinase SYK inhibitor
    CAS: 841290-80-0 EC Number: 617-533-5 PubChem CID: 11213558 Formula: C22H23FN6O5 Molecular Weight: 470.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: R129910
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    IUPAC Name
    6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
    SMILES
    CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
    InChIKey
    NHHQJBCNYHBUSI-UHFFFAOYSA-N
    InChI
    1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,show more
    Synonyms
    HY-11108 | 2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE,6-[[5-FLUORO-2-[(3,4,5-TRIMETHOXPHENYL)AMINO]-4-PYRIMIDINYL]AMINO]-2...
  4. RAF265 (CHIR-265), Vascular endothelial growth factor receptor 2 inhibitor
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    RAF265 (CHIR-265), Vascular endothelial growth factor receptor 2 inhibitor
    CAS: 927880-90-8 PubChem CID: 11656518 Formula: C24H16F6N6O Molecular Weight: 518.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: R127906
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    IUPAC Name
    1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine
    SMILES
    CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
    InChIKey
    YABJJWZLRMPFSI-UHFFFAOYSA-N
    InChI
    1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,show more
    Synonyms
    CHIR265 | CHIR-265 | FT-0746327 | HMS3672I21 | NCGC00015003-02 | 1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)py...
  5. PLX-4720, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of kinase insert domain receptor
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    PLX-4720, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of kinase insert domain receptor
    CAS: 918505-84-7 EC Number: 894-417-2 Formula: C17H14ClF2N3O3S Molecular Weight: 413.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: P127903
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    IUPAC Name
    N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
    SMILES
    CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)Cl)F
    InChIKey
    YZDJQTHVDDOVHR-UHFFFAOYSA-N
    InChI
    1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22)
    Synonyms
    AKOS015919071 | N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide | HMS3750K11 | N-[3-(...
  6. Nilotinib (AMN-107), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2
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    Nilotinib (AMN-107), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2
    CAS: 641571-10-0 EC Number: 700-544-5 Formula: C28H22F3N7O Molecular Weight: 529.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: N126111
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    IUPAC Name
    4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
    InChIKey
    HHZIURLSWUIHRB-UHFFFAOYSA-N
    InChI
    1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2Hshow more
    Synonyms
    Nilotinib [USAN:INN:BAN] | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trif...
  7. OSI-930, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine
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    OSI-930, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine
    CAS: 728033-96-3 Formula: C22H16F3N3O2S Molecular Weight: 443.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: O126155
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    IUPAC Name
    3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide
    SMILES
    C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
    InChIKey
    FGTCROZDHDSNIO-UHFFFAOYSA-N
    InChI
    1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)
    Synonyms
    AKOS026750567 | BDBM50356877 | SMR004701347 | HMS3295O11 | OSI 930 | NSC800811 | NSC-800811 | CELASTROL [MI] | CHEBI:...
  8. Ki8751
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    Ki8751
    CAS: 228559-41-9 Formula: C24H18F3N3O4 Molecular Weight: 469.41
    ≥98%
    In Stock Item #: K125876
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    Technical Identifiers
    IUPAC Name
    1-(2,4-difluorophenyl)-3-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-fluorophenyl]urea
    SMILES
    COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F
    InChIKey
    LFKQSJNCVRGFCC-UHFFFAOYSA-N
    InChI
    1S/C24H18F3N3O4/c1-32-22-11-15-20(12-23(22)33-2)28-8-7-21(15)34-14-4-6-19(17(27)10-14)30-24(31)29-18-5-3-13(25)9-16(18)26/h3-12H,1-2H3,(H2,29,30,31)
    Synonyms
    1-(2,4-difluorophenyl)-3-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea | HMS1787L13 | SB19355 | BRD-K47150...
  9. Vatalanib succinate
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    Vatalanib succinate
    CAS: 212142-18-2 EC Number: 658-085-0 PubChem CID: 151193 Formula: C20H15ClN4•C4H6O4 Molecular Weight: 464.90
    ≥99%(HPLC)
    In Stock Item #: V286725
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    IUPAC Name
    butanedioic acid;N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
    SMILES
    C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.C(CC(=O)O)C(=O)O
    InChIKey
    LLDWLPRYLVPDTG-UHFFFAOYSA-N
    InChI
    1S/C20H15ClN4.C4H6O4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;5-3(6)1-2-4(7)8/h1-12H,13H2,(H,23,25);1-2H2,(H,5,6show more
    Synonyms
    1-(4-chloroanilino)-4-(4-pyridylmethyl)phthalazine succinate | PTK 787/ZK 222584 | 1-Phthalazinamine, N-(4-chlorophen...
  10. Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor
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    Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor
    CAS: 444731-52-6 EC Number: 963-764-2 Formula: C21H23N7O2S Molecular Weight: 437.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: P125184
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    IUPAC Name
    5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
    SMILES
    CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
    InChIKey
    CUIHSIWYWATEQL-UHFFFAOYSA-N
    InChI
    1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
    Synonyms
    5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide | 5-[[4-[(2,3-d...
  11. Linifanib (ABT-869), Vascular endothelial growth factor receptor inhibitor
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    Linifanib (ABT-869), Vascular endothelial growth factor receptor inhibitor
    CAS: 796967-16-3 EC Number: 681-638-2 Formula: C21H18FN5O Molecular Weight: 375.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L126993
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    IUPAC Name
    1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
    SMILES
    CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
    InChIKey
    MPVGZUGXCQEXTM-UHFFFAOYSA-N
    InChI
    1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
    Synonyms
    A19393 | D09635 | A-741439 | FT-0696226 | LINIFANIB [INN] | NSC764237 | NSC-764237 | CCG-264767 | J-503186 | Linifani...
  12. Pexidartinib - Moligand™, ≥98% CAS No(1029044-16-3) by Aladdin Scientific
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    Pexidartinib, Stem cell growth factor receptor inhibitor
    CAS: 1029044-16-3 Formula: C20H15ClF3N5 Molecular Weight: 417.81
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P171724
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    IUPAC Name
    5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
    SMILES
    C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F
    InChIKey
    JGWRKYUXBBNENE-UHFFFAOYSA-N
    InChI
    1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29)
    Synonyms
    CML-261 | D11270 | PEXIDARTINIB [MI] | N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluor...
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