CD28
22 produtos
Produtos
- MDK 24720 (CTLA-4 inhibitor)CAS: 635324-72-0 Fórmula: C21H13F4N5O Peso molecular: 427.35● Em estoque — Armazém nos EUA, envio para a EU* Item #: M412249Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 4-(4-fluorophenyl)-10-methyl-7-[3-(trifluoromethyl)phenyl]-3,4,8,10,11-pentazatricyclo[7.3.0.02,6]dodeca-1,6,8,11-tetraen-5-one
- SMILES
- CN1C2=NC(=C3C(=C2C=N1)NN(C3=O)C4=CC=C(C=C4)F)C5=CC(=CC=C5)C(F)(F)F
- InChIKey
- WQKVVTLTCHDAST-UHFFFAOYSA-N
- InChI
- 1S/C21H13F4N5O/c1-29-19-15(10-26-29)18-16(20(31)30(28-18)14-7-5-13(22)6-8-14)17(27-19)11-3-2-4-12(9-11)21(23,24)25/h2-10,28H,1H3
- Sinónimos
- 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one | B7/...
- Tiragolumab (anti-TIGIT), INHIBITOR of T-cell immunoreceptor with Ig and ITIM domains inhibitorCAS: 1918185-84-8Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● Em estoque — Armazém nos EUA, envio para a EU* Item #: Ab169250Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Associated targets
- TIGIT
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Espécies reativas
- Cynomolgus monkey, Human, Rabbit
- Isótipo
- Human IgG1
- Espécie hospedeira
- Human
- Conjugação
- Unconjugated
- Sinónimos
- RG6058 | MTIG7192A | T cell immunoreceptor with Ig and ITIM domains | TIGIT | VSIG9 | VSTM3 | WUCAM | DKFZp667A205 an...
- Prezalumab (anti-B7-H2)CAS: 1523164-68-2Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● Em estoque — Armazém nos EUA, envio para a EU* Item #: Ab170952Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Associated targets
- ICOSLG
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Espécies reativas
- Cynomolgus monkey, Human, Mouse
- Isótipo
- Human IgG2SA
- Espécie hospedeira
- Human
- Conjugação
- Unconjugated
- Sinónimos
- B7 H2 antibody | B7 homolog 2 antibody | B7 homologue 2 antibody | B7 like protein Gl50 antibody | B7 related protein...
- Galiximab (anti-CD80), INHIBITOR of T-lymphocyte activation antigen CD80 inhibitorCAS: 357613-77-5Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● Em estoque — Armazém nos EUA, envio para a EU* Item #: Ab177850Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Associated targets
- CD80
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Espécies reativas
- Cynomolgus monkey, Human
- Isótipo
- Human IgG1
- Espécie hospedeira
- Human
- Conjugação
- Unconjugated
- Sinónimos
- Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
- CD80-IN-3Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Sob encomenda · 8–12 semanas Item #: C651374Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid
- SMILES
- C1=CC2=C3C(=CN=C2C(=C1)F)C(=O)N(N3)C4=CC=C(C=C4)C(=O)O
- InChIKey
- NLGJRBLPUVEYKC-UHFFFAOYSA-N
- InChI
- 1S/C17H10FN3O3/c18-13-3-1-2-11-14-12(8-19-15(11)13)16(22)21(20-14)10-6-4-9(5-7-10)17(23)24/h1-8,20H,(H,23,24)
- Sinónimos
- LBEWFVRAHKOLOU-UHFFFAOYSA-N | CD80-IN-3 | benzoic acid, 4-(6-fluoro-3,5-dihydro-3-oxo-2H-pyrazolo[4,3-c]quinolin-2-yl...
- Theralizumab (anti-CD28)CAS: 906068-56-2Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● Em estoque — Armazém nos EUA, envio para a EU* Item #: Ab190136Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Associated targets
- CD28
- Short Overview
- Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Espécies reativas
- Human
- Isótipo
- Human IgG4
- Espécie hospedeira
- Human
- Conjugação
- Unconjugated
- SMILES
- [Theralizumab]
- Sinónimos
- CD 28 antibody | CD28 antibody | CD28 antigen antibody | CD28 molecule antibody | CD28_HUMAN antibody | MGC138290 ant...
- AcazicolceptCAS: 2797026-97-0◐ .Sob encomenda · 8–12 semanas Item #: A1434024Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Calcium influx inducer compound 634CAS: 882291-37-4 Fórmula: C15H15N3O4S3 Peso molecular: 397.49◐ .Sob encomenda · 8–12 semanas Item #: C1433867Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- FR104◐ .Sob encomenda · 8–12 semanas Item #: F1434023Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- ICOS-IN-1CAS: 1006002-58-9 Fórmula: C17H14Cl2N2O2 Peso molecular: 349.21◐ .Sob encomenda · 8–12 semanas Item #: I1433868Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- M04CAS: 875158-73-9 Fórmula: C18H24N2O4S3 Peso molecular: 428.59◐ .Sob encomenda · 8–12 semanas Item #: M1424244Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- KY-1044CAS: 2489390-15-8◐ .Sob encomenda · 8–12 semanas Item #: K1434021Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
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Perguntas frequentes
How is the CD28 listing put together?
It draws on reported CD28 annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CD28 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CD28 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CD28 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CD28 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CD28 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CD28 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.