Immunology/Inflammation - FLAP Supplier | High Purity

Produtos

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MK-0591
CAS: 136668-42-3 Fórmula: C₃₄H₃₅ClN₂O₃S Peso molecular: 587.17

≥98%

● Em estoque — Armazém nos EUA, envio para a EU* Item #: M125295
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Nome IUPAC

3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid

SMILES

CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O

InChIKey

NZOONKHCNQFYCI-UHFFFAOYSA-N

InChI

1S/C34H35ClN2O3S/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39/h6-show more

Sinónimos
SB19076 | MK 0591 | 3-(tert-Butylthio)-1-(p-chlorobenzyl)-alpha,alpha-dimethyl-5-(2-quinolylmethoxy)indole-2-propioni...
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MK-591 sodium
CAS: 147030-01-1 Fórmula: C₃₄H₃₄ClN₂NaO₃S Peso molecular: 609.15

≥98%

◐ .Sob encomenda · 8–12 semanas Item #: M125732
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Nome IUPAC

sodium;3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoate

SMILES

CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)[O-].[Na+]

InChIKey

YPURUCMVRRNPHJ-UHFFFAOYSA-M

InChI

1S/C34H35ClN2O3S.Na/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39;show more

Sinónimos
321US0I5R6 | sodium 3-[1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)-3-tert-butylsulfanyl-indol-2-yl]-2,2-dimet...
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MK886, Antagonist of Peroxisome proliferator-activated receptor-α
CAS: 118414-82-7 Fórmula: C₂₇H₃₄ClNO₂S Peso molecular: 472.08

Solid Moligand™ ? ≥98%

● Em estoque — Armazém nos EUA, envio para a EU* Item #: M275434
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Nome IUPAC

3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid

SMILES

CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl

InChIKey

QAOAOVKBIIKRNL-UHFFFAOYSA-N

InChI

1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31)

Sinónimos
1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-?,?-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid | 3-...
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AM679
CAS: 1206880-66-1 PubChem CID: 44627267 Fórmula: C₄₀H₄₄N₄O₅S Peso molecular: 692.87

Solid ≥99%

◐ .Sob encomenda · 8–12 semanas Item #: A127302
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Nome IUPAC

3-[5-[[(2S)-1-acetyl-2,3-dihydroindol-2-yl]methoxy]-3-tert-butylsulfanyl-1-[[4-(5-methoxypyrimidin-2-yl)phenyl]methyl]indol-2-yl]-2,2-dimethylpropanoishow more

SMILES

CC(=O)N1C(CC2=CC=CC=C21)COC3=CC4=C(C=C3)N(C(=C4SC(C)(C)C)CC(C)(C)C(=O)O)CC5=CC=C(C=C5)C6=NC=C(C=N6)OC

InChIKey

VYXWHVDEWWHDLH-LJAQVGFWSA-N

InChI

1S/C40H44N4O5S/c1-25(45)44-29(18-28-10-8-9-11-33(28)44)24-49-30-16-17-34-32(19-30)36(50-39(2,3)4)35(20-40(5,6)38(46)47)43(34)23-26-12-14-27(15-13-26)3show more

Sinónimos
(S)-3-(5-((1-acetylindolin-2-yl)methoxy)-3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-1H-indol-2-yl)-2,2-...
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LNT 1
CAS: 824983-91-7 Fórmula: C₁₅H₁₂N₂O₅S Peso molecular: 332.33

≥98%(HPLC)

● Em estoque — Armazém nos EUA, envio para a EU* Item #: L288189
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Nome IUPAC

1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4-dione

SMILES

C1C(OC2=CC=CC=C2O1)CN3C4=C(C(=O)N(C3=O)O)SC=C4

InChIKey

MXQGCMQXTPTJJT-UHFFFAOYSA-N

InChI

1S/C15H12N2O5S/c18-14-13-10(5-6-23-13)16(15(19)17(14)20)7-9-8-21-11-3-1-2-4-12(11)22-9/h1-6,9,20H,7-8H2

Sinónimos
1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione
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BAY-X 1005, 5-lipoxygenase activating protein inhibitor
CAS: 128253-31-6 Fórmula: C₂₃H₂₃NO₃ Peso molecular: 361.43

Moligand™ ? ≥98%(HPLC)

◐ .Sob encomenda · 8–12 semanas Item #: B288165
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Identificadores técnicos

Nome IUPAC

(2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid

SMILES

C1CCC(C1)C(C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O

InChIKey

ZEYYDOLCHFETHQ-JOCHJYFZSA-N

InChI

1S/C23H23NO3/c25-23(26)22(17-6-1-2-7-17)18-10-13-20(14-11-18)27-15-19-12-9-16-5-3-4-8-21(16)24-19/h3-5,8-14,17,22H,1-2,6-7,15H2,(H,25,26)/t22-/m1/s1

Sinónimos
(2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid | (R)-Cyclopentyl-[4-(quinolin-2-ylmethoxy)-phenyl]-...
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FEN1-IN-4
CAS: 1995893-58-7 Fórmula: C₁₂H₁₂N₂O₃ Peso molecular: 232.24

10mM in DMSO

● Em estoque — Armazém nos EUA, envio para a EU* Item #: F422425
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Nome IUPAC

1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4-dione

SMILES

C1CC1CN2C3=CC=CC=C3C(=O)N(C2=O)O

InChIKey

JAFLWTUYSKADJS-UHFFFAOYSA-N

InChI

1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2

Sinónimos
FEN1 Inhibitor C2 | JUN935872,4(1H,3H)-Quinazolinedione,1-(cyclopropylmethyl)-3-hydroxy-
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FEN1-IN-4
CAS: 1995893-58-7 Fórmula: C₁₂H₁₂N₂O₃ Peso molecular: 232.24

Solid ≥99%

● Em estoque — Armazém nos EUA, envio para a EU* Item #: F412918
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Nome IUPAC

1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4-dione

SMILES

C1CC1CN2C3=CC=CC=C3C(=O)N(C2=O)O

InChIKey

JAFLWTUYSKADJS-UHFFFAOYSA-N

InChI

1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2

Sinónimos
FEN1 Inhibitor C2 | JUN93587
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MK886, Antagonist of Peroxisome proliferator-activated receptor-α
CAS: 118414-82-7 Fórmula: C₂₇H₃₄ClNO₂S Peso molecular: 472.08

Moligand™ ? 10mM in DMSO

● Em estoque — Armazém nos EUA, envio para a EU* Item #: M420810
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Nome IUPAC

3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid

SMILES

CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl

InChIKey

QAOAOVKBIIKRNL-UHFFFAOYSA-N

InChI

1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31)

Sinónimos
1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-?,?-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid | 3-...
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Diflapolin, Inhibitor of epoxide hydrolase 2
CAS: 724453-98-9 PubChem CID: 4560409 Fórmula: C₂₂H₁₇Cl₂N₃O₂S Peso molecular: 458.36

Moligand™ ? ≥98%

● Em estoque — Armazém nos EUA, envio para a EU* Item #: D609883
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Identificadores técnicos

Nome IUPAC

1-[4-(1,3-benzothiazol-2-ylmethoxy)-2-methylphenyl]-3-(3,4-dichlorophenyl)urea

SMILES

CC1=C(C=CC(=C1)OCC2=NC3=CC=CC=C3S2)NC(=O)NC4=CC(=C(C=C4)Cl)Cl

InChIKey

FGXLEECGXSDIMM-UHFFFAOYSA-N

InChI

1S/C22H17Cl2N3O2S/c1-13-10-15(29-12-21-26-19-4-2-3-5-20(19)30-21)7-9-18(13)27-22(28)25-14-6-8-16(23)17(24)11-14/h2-11H,12H2,1H3,(H2,25,27,28)
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Fiboflapon sodium, 5-lipoxygenase activating protein inhibitor
CAS: 1196070-26-4 Número CE: 689-173-7 PubChem CID: 44473150 Fórmula: C₃₈H₄₂N₃NaO₄S Peso molecular: 659.81

≥99%

◐ .Sob encomenda · 8–12 semanas Item #: F647997
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Nome IUPAC

sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate

SMILES

CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)[O-])SC(C)(C)C.[Na+]

InChIKey

NOJNFULGOQGBKB-UHFFFAOYSA-M

InChI

1S/C38H43N3O4S.Na/c1-8-44-34-18-14-28(22-40-34)27-12-10-26(11-13-27)23-41-32-17-16-30(45-24-29-15-9-25(2)21-39-29)19-31(32)35(46-37(3,4)5)33(41)20-38(show more

Sinónimos
GSK2190915 sodium salt | SCHEMBL1254527 | sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5...
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AM103
CAS: 1147872-22-7 PubChem CID: 129010507 Fórmula: C₃₆H₃₈N₃NaO₄S Peso molecular: 631.76

≥99%

◐ .Sob encomenda · 8–12 semanas Item #: A647147
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Identificadores técnicos

SMILES

CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=CC=CC=N3)CC4=CC=C(C=C4)C5=CN=C(C=C5)OC)CC(C)(C)C(=O)O.[Na]

InChIKey

VANSVYMYESBUFV-UHFFFAOYSA-N

InChI

1S/C36H39N3O4S.Na/c1-35(2,3)44-33-29-19-28(43-23-27-9-7-8-18-37-27)15-16-30(29)39(31(33)20-36(4,5)34(40)41)22-24-10-12-25(13-11-24)26-14-17-32(42-6)38show more

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Perguntas frequentes

Which compounds are listed for FLAP?

Compounds associated with FLAP are grouped here under the Immunology/Inflammation classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.

How does FLAP sit within Immunology/Inflammation?

FLAP is one target listing within the Immunology/Inflammation classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.

What data should I check before ordering a compound from FLAP?

For compounds listed under FLAP, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

How do I find related targets or backup compounds for FLAP?

Browse the parent Immunology/Inflammation listing to reach targets neighbouring FLAP, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.