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Cyclic GMP-AMP Synthase

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  1. HA-1004
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    HA-1004
    CAS: 91742-10-8 Formula: C12H15N5O2S Molecular Weight: 293.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: H331174
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    Technical Identifiers
    IUPAC Name
    2-[2-(isoquinolin-5-ylsulfonylamino)ethyl]guanidine
    SMILES
    C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN=C(N)N
    InChIKey
    MZNDNBFMSVMUCX-UHFFFAOYSA-N
    InChI
    1S/C12H15N5O2S/c13-12(14)16-6-7-17-20(18,19)11-3-1-2-9-8-15-5-4-10(9)11/h1-5,8,17H,6-7H2,(H4,13,14,16)
    Synonyms
    HA 1004 | HA1004 | ha-1004 | N-(2-((Aminoiminomethyl)amino)ethyl)-5-isoquinolinesulfonamide | HT 1004 | KBio2_005589 ...
  2. Decoyinine
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    Decoyinine
    CAS: 2004-04-8 Formula: C11H13N5O4 Molecular Weight: 279.25
    Solid ≥99%
    In Stock Item #: D302707
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    Technical Identifiers
    IUPAC Name
    (2R,3R,4S)-2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylideneoxolane-3,4-diol
    SMILES
    C=C1C(C(C(O1)(CO)N2C=NC3=C(N=CN=C32)N)O)O
    InChIKey
    UZSSGAOAYPICBZ-SOCHQFKDSA-N
    InChI
    1S/C11H13N5O4/c1-5-7(18)8(19)11(2-17,20-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-4,7-8,17-19H,1-2H2,(H2,12,13,14)/t7-,8-,11-/m1/s1
    Synonyms
    (2R,3R,4S)-2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylene-tetrahydrofuran-3,4-diol | AS-56364 | CCG-208190 | NCG...
  3. G150
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    G150
    CAS: 2369751-30-2 Formula: C18H16Cl2N4O2 Molecular Weight: 391.25
    ≥98%
    In Stock Item #: G414285
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    Technical Identifiers
    IUPAC Name
    1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
    SMILES
    C1CN(CC2=C1NC3=C2C(=CC(=C3Cl)Cl)C4=CN=C(C=C4)N)C(=O)CO
    InChIKey
    VVUOUIPXYFIWLE-UHFFFAOYSA-N
    InChI
    1S/C18H16Cl2N4O2/c19-12-5-10(9-1-2-14(21)22-6-9)16-11-7-24(15(26)8-25)4-3-13(11)23-18(16)17(12)20/h1-2,5-6,23,25H,3-4,7-8H2,(H2,21,22)
    Synonyms
    1-(9-(6-Aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one | 1-​[9-​...
  4. G150
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    G150
    CAS: 2369751-30-2 Formula: C18H16Cl2N4O2 Molecular Weight: 391.25
    10mM in DMSO
    In Stock Item #: G422778
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    Technical Identifiers
    IUPAC Name
    1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
    SMILES
    C1CN(CC2=C1NC3=C2C(=CC(=C3Cl)Cl)C4=CN=C(C=C4)N)C(=O)CO
    InChIKey
    VVUOUIPXYFIWLE-UHFFFAOYSA-N
    InChI
    1S/C18H16Cl2N4O2/c19-12-5-10(9-1-2-14(21)22-6-9)16-11-7-24(15(26)8-25)4-3-13(11)23-18(16)17(12)20/h1-2,5-6,23,25H,3-4,7-8H2,(H2,21,22)
    Synonyms
    Ethanone,1-​[9-​(6-​amino-​3-​pyridinyl)​-​6,​7-​dichloro-​1,​3,​4,​5-​tetrahydro-​2H-​pyrido[4,​3-​b]​indol-​2-​yl]​-...
  5. IRAK4-IN-4
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    IRAK4-IN-4
    CAS: 1850276-58-2 Formula: C22H16N2O2 Molecular Weight: 340.37
    ≥98%
    In Stock Item #: I412539
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    Technical Identifiers
    IUPAC Name
    1-(7-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione
    SMILES
    CC1=CC2=NC(=C(N2C=C1)C(=O)C(=O)C3=CC=CC=C3)C4=CC=CC=C4
    InChIKey
    AHNNWZOVCRQAAH-UHFFFAOYSA-N
    InChI
    1S/C22H16N2O2/c1-15-12-13-24-18(14-15)23-19(16-8-4-2-5-9-16)20(24)22(26)21(25)17-10-6-3-7-11-17/h2-14H,1H3
    Synonyms
    1,​2-​Ethanedione,1-​(7-​methyl-​2-​phenylimidazo[1,​2-​a]​pyridin-​3-​yl)​-​2-​phenyl-
  6. IRAK4-IN-4
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    IRAK4-IN-4
    CAS: 1850276-58-2 Formula: C22H16N2O2 Molecular Weight: 340.37
    10mM in DMSO
    In Stock Item #: I422266
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    Technical Identifiers
    IUPAC Name
    1-(7-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione
    SMILES
    CC1=CC2=NC(=C(N2C=C1)C(=O)C(=O)C3=CC=CC=C3)C4=CC=CC=C4
    InChIKey
    AHNNWZOVCRQAAH-UHFFFAOYSA-N
    InChI
    1S/C22H16N2O2/c1-15-12-13-24-18(14-15)23-19(16-8-4-2-5-9-16)20(24)22(26)21(25)17-10-6-3-7-11-17/h2-14H,1H3
    Synonyms
    1,​2-​Ethanedione,1-​(7-​methyl-​2-​phenylimidazo[1,​2-​a]​pyridin-​3-​yl)​-​2-​phenyl-
  7. PF-06928215, Inhibitor of Cyclic GMP-AMP synthase
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    PF-06928215, Inhibitor of Cyclic GMP-AMP synthase
    CAS: 2378173-15-8 PubChem CID: 137300622 Formula: C20H20N4O4 Molecular Weight: 380.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P420009
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    Technical Identifiers
    IUPAC Name
    (1R,2S)-2-[(7-oxo-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid
    SMILES
    C1CCC(C(C1)C(=O)O)NC(=O)C2=CNN3C2=NC(=CC3=O)C4=CC=CC=C4
    InChIKey
    WGQGCLHXUPGUSZ-HIFRSBDPSA-N
    InChI
    1S/C20H20N4O4/c25-17-10-16(12-6-2-1-3-7-12)22-18-14(11-21-24(17)18)19(26)23-15-9-5-4-8-13(15)20(27)28/h1-3,6-7,10-11,13,15,21H,4-5,8-9H2,(H,23,26)(H,2show more
  8. RU.521
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    RU.521
    CAS: 2262452-06-0 PubChem CID: 135397653 Formula: C19H12Cl2N4O3 Molecular Weight: 415.23
    ≥99%
    In Stock Item #: R413655
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    Technical Identifiers
    IUPAC Name
    2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-(3-oxo-1H-2-benzofuran-1-yl)-1H-pyrazol-3-one
    SMILES
    CC1=C(C(=O)N(N1)C2=NC3=C(N2)C=CC(=C3Cl)Cl)C4C5=CC=CC=C5C(=O)O4
    InChIKey
    IAWZUQAOMURCLV-UHFFFAOYSA-N
    InChI
    1S/C19H12Cl2N4O3/c1-8-13(16-9-4-2-3-5-10(9)18(27)28-16)17(26)25(24-8)19-22-12-7-6-11(20)14(21)15(12)23-19/h2-7,16,24H,1H3,(H,22,23)
    Synonyms
    RU320521 | 3-[1-(6,7-dichloro-1H-benzimidazol-2-yl)-5-hydroxy-3-methyl-pyrazol-4-yl]-3H-isobenzofuran-1-one
  9. RU.521
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    RU.521
    CAS: 2262452-06-0 PubChem CID: 135397653 Formula: C19H12Cl2N4O3 Molecular Weight: 415.23
    10mM in DMSO
    Out of Stock Item #: R422715
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-(3-oxo-1H-2-benzofuran-1-yl)-1H-pyrazol-3-one
    SMILES
    CC1=C(C(=O)N(N1)C2=NC3=C(N2)C=CC(=C3Cl)Cl)C4C5=CC=CC=C5C(=O)O4
    InChIKey
    IAWZUQAOMURCLV-UHFFFAOYSA-N
    InChI
    1S/C19H12Cl2N4O3/c1-8-13(16-9-4-2-3-5-10(9)18(27)28-16)17(26)25(24-8)19-22-12-7-6-11(20)14(21)15(12)23-19/h2-7,16,24H,1H3,(H,22,23)
    Synonyms
    RU320521 | 3-[1-(6,7-dichloro-1H-benzimidazol-2-yl)-5-hydroxy-3-methyl-pyrazol-4-yl]-3H-isobenzofuran-1-one
  10. G140
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    G140
    CAS: 2369751-07-3 PubChem CID: 139388865 Formula: C17H16Cl2N4O2 Molecular Weight: 379.24
    Solid ≥98%
    Out of Stock Item #: G647730
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    Technical Identifiers
    IUPAC Name
    1-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
    SMILES
    CN1C=CC(=N1)C2=CC(=C(C3=C2C4=C(N3)CCN(C4)C(=O)CO)Cl)Cl
    InChIKey
    NVPFAXHXXODQRO-UHFFFAOYSA-N
    InChI
    1S/C17H16Cl2N4O2/c1-22-4-2-13(21-22)9-6-11(18)16(19)17-15(9)10-7-23(14(25)8-24)5-3-12(10)20-17/h2,4,6,20,24H,3,5,7-8H2,1H3
    Synonyms
    1-(6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone | T015T-01...
  12. CU-76
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    CU-76
    CAS: 2400954-58-5 PubChem CID: 156588964
    Out of Stock Item #: C1434277
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    Technical Identifiers
    IUPAC Name
    methyl 4-amino-6-(3,5-difluoro-4-iodoanilino)-1,3,5-triazine-2-carboxylate
    SMILES
    COC(=O)C1=NC(=NC(=N1)NC2=CC(=C(C(=C2)F)I)F)N
    InChIKey
    DATILFYUDSRBBK-UHFFFAOYSA-N
    InChI
    1S/C11H8F2IN5O2/c1-21-9(20)8-17-10(15)19-11(18-8)16-4-2-5(12)7(14)6(13)3-4/h2-3H,1H3,(H3,15,16,17,18,19)
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