PKUMDL WQ 2101 - ≥98%(HPLC) , CAS No.304481-72-9

CAS: 304481-72-9 Cat. No.: P287595 Molecular Weight: 317.25 PubChem CID: 135781546

GRADE & PURITY ≥98%(HPLC)

Synonyms

2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide | PKUMDL-WQ-2101

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

2, 4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide | PKUMDL-WQ-2101

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50= 34.8 μM). Exhibits antitumor activityin vitroin breast cancer cells lines overexpressing PHGDH (EC50values are 7.7 and 10.8 μM in MDA-MB-468 and HCC-70 cells, respectively). I

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%(HPLC)

Names and Identifiers

• Canonical Smiles: C1=CC(=C(C=C1[N+](=O)[O-])C=NNC(=O)C2=C(C=C(C=C2)O)O)O
• IUPAC Name: 2,4-dihydroxy-N-[(Z)-(2-hydroxy-5-nitrophenyl)methylideneamino]benzamide
• InChIKey: OXONIXZPWKJHMW-CHHVJCJISA-N
• INCHI: 1S/C14H11N3O6/c18-10-2-3-11(13(20)6-10)14(21)16-15-7-8-5-9(17(22)23)1-4-12(8)19/h1-7,18-20H,(H,16,21)/b15-7-
• PubChem CID: 135781546
• Molecular Weight: 317.25

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 31.73, Max Conc. mM: 100