for GC derivatization

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for GC derivatization

GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds.

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  1. N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide(MTBSTFA)
    CAS: 77377-52-7 EC Number: 616-455-9 Formula: CF3CON(CH3)Si(CH3)2C(CH3)3 Molecular Weight: 241.33
    Liquid for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds.
    In Stock Item #: N131645
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    Technical Identifiers
    IUPAC Name
    N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
    SMILES
    CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
    InChIKey
    QRKUHYFDBWGLHJ-UHFFFAOYSA-N
    InChI
    1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3
    Synonyms
    MTBSTFA | Acetamide, N-((1,1-dimethylethyl)dimethylsilyl)-2,2,2-trifluoro-N-methyl- | Acetamide, N-[(1,1-dimethylethy...
  2. N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide(MTBSTFA)
    CAS: 77377-52-7 EC Number: 616-455-9 Formula: CF3CON(CH3)Si(CH3)2C(CH3)3 Molecular Weight: 241.33
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥97% with 1% TBDMSCl
    In Stock Item #: N121507
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    Technical Identifiers
    IUPAC Name
    N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
    SMILES
    CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
    InChIKey
    QRKUHYFDBWGLHJ-UHFFFAOYSA-N
    InChI
    1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3
    Synonyms
    Acetamide, N-((1,1-dimethylethyl)dimethylsilyl)-2,2,2-trifluoro-N-methyl- | Acetamide, N-[(1,1-dimethylethyl)dimethyl...
  3. Pentafluoropropionic Acid Anhydride(PFAA)
    CAS: 356-42-3 EC Number: 206-604-2 Formula: C6F10O3 Molecular Weight: 310.05
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥99%
    In Stock Item #: P122803
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    Technical Identifiers
    IUPAC Name
    2,2,3,3,3-pentafluoropropanoyl 2,2,3,3,3-pentafluoropropanoate
    SMILES
    C(=O)(C(C(F)(F)F)(F)F)OC(=O)C(C(F)(F)F)(F)F
    InChIKey
    XETRHNFRKCNWAJ-UHFFFAOYSA-N
    InChI
    1S/C6F10O3/c7-3(8,5(11,12)13)1(17)19-2(18)4(9,10)6(14,15)16
    Synonyms
    PFAA | 0LFE7U11O5 | AKOS005063449 | PENTAFLUOROPROPIONYL ANHYDRIDE | Propanoic acid, pentafluoro-, anhydride | 2,2,3,...
  4. N,O-Bis(trimethylsilyl)trifluoroacetamide(BSTFA)
    CAS: 25561-30-2 EC Number: 247-103-9 Formula: C8H18F3NOSi2 Molecular Weight: 257.4
    Liquid for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥98%(GC)
    In Stock Item #: B118472
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    Technical Identifiers
    IUPAC Name
    trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate
    SMILES
    C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C
    InChIKey
    XCOBLONWWXQEBS-UHFFFAOYSA-N
    InChI
    1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3
    Synonyms
    NSC 379423 | Q1281115 | (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propano...
  5. N,O-Bis(trimethylsilyl)trifluoroacetamide
    CAS: 25561-30-2 EC Number: 247-103-9 Formula: C8H18F3NOSi2 Molecular Weight: 257.4
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. 10% TMCS
    In Stock Item #: B299117
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate
    SMILES
    C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C
    InChIKey
    XCOBLONWWXQEBS-UHFFFAOYSA-N
    InChI
    1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3
    Synonyms
    NSC 379423 | Q1281115 | (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propano...
  6. TMS-BA
    CAS: 10416-59-8 EC Number: 233-892-7 Formula: C8H21NOSi2 Molecular Weight: 203.43
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds.
    In Stock Item #: T131644
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    Technical Identifiers
    IUPAC Name
    trimethylsilyl N-trimethylsilylethanimidate
    SMILES
    CC(=N[Si](C)(C)C)O[Si](C)(C)C
    InChIKey
    SIOVKLKJSOKLIF-UHFFFAOYSA-N
    InChI
    1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3
    Synonyms
    B0510 | DTXSID5051525 | D72517 | Trimethylsilyl N-(trimethylsilyl)ethanimidoate | TMS-BA | N-trimethylsilyl-acetylimi...
  7. Ethyl hexafluoroglutaryl chloride
    CAS: 18381-53-8 Formula: C7H5ClF6O3 Molecular Weight: 286.56
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥97%
    In Stock Item #: E131614
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    Technical Identifiers
    IUPAC Name
    ethyl 5-chloro-2,2,3,3,4,4-hexafluoro-5-oxopentanoate
    SMILES
    CCOC(=O)C(C(C(C(=O)Cl)(F)F)(F)F)(F)F
    InChIKey
    OLRXGDHRDQKNGW-UHFFFAOYSA-N
    InChI
    1S/C7H5ClF6O3/c1-2-17-4(16)6(11,12)7(13,14)5(9,10)3(8)15/h2H2,1H3
    Synonyms
    ethyl 5-chloro-2,2,3,3,4,4-hexafluoro-5-oxopentanoate | 4-Carbethoxyhexafluorobutyryl chloride | Ethyl Hexafluoroglut...
  8. Hexamethyl disilylamine(HMDS)
    CAS: 999-97-3 EC Number: 213-668-5 Formula: C6H19NSi2 Molecular Weight: 161.39
    Liquid for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥99%(GC)
    In Stock Item #: H106018
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    Technical Identifiers
    IUPAC Name
    [dimethyl-(trimethylsilylamino)silyl]methane
    SMILES
    C[Si](C)(C)N[Si](C)(C)C
    InChIKey
    FFUAGWLWBBFQJT-UHFFFAOYSA-N
    InChI
    1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
    Synonyms
    Hexamethyldisilazane|999-97-3|Bis(trimethylsilyl)amine|HMDS|1,1,1,3,3,3-Hexamethyldisilazane|Hexamethylsilazane|Silan...
  9. N-Methyl-N-(trimethylsilyl)trifluoroacetamide(MSTFA)
    CAS: 24589-78-4 EC Number: 246-331-6 Formula: C6H12F3NOSi Molecular Weight: 199.25
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥98.5%(GC)
    In Stock Item #: M106662
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2,2,2-trifluoro-N-methyl-N-trimethylsilylacetamide
    SMILES
    CN(C(=O)C(F)(F)F)[Si](C)(C)C
    InChIKey
    MSPCIZMDDUQPGJ-UHFFFAOYSA-N
    InChI
    1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
    Synonyms
    MSTFA | N-Methyl-N-trimethylsilyltrifluoroacetamide | ACETAMIDE, 2,2,2-TRIFLUORO-N-METHYL-N-(TRIMETHYLSILYL)- | N-Met...
  10. Heptafluorobutyric anhydride(HFAA)
    CAS: 336-59-4 EC Number: 206-410-8 Formula: C8F14O3 Molecular Weight: 410.06
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥99%
    Out of Stock Item #: H122092
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    Technical Identifiers
    IUPAC Name
    2,2,3,3,4,4,4-heptafluorobutanoyl 2,2,3,3,4,4,4-heptafluorobutanoate
    SMILES
    C(=O)(C(C(C(F)(F)F)(F)F)(F)F)OC(=O)C(C(C(F)(F)F)(F)F)(F)F
    InChIKey
    UFFSXJKVKBQEHC-UHFFFAOYSA-N
    InChI
    1S/C8F14O3/c9-3(10,5(13,14)7(17,18)19)1(23)25-2(24)4(11,12)6(15,16)8(20,21)22
    Synonyms
    BCP22497 | Heptafluorobutyric anhydride | HEPTAFLUOROBUTYRYL ANHYDRIDE | Heptafluorobutanoic anhydride | J-521428 | B...
  11. N-Heptafluorobutyrylimidazole
    CAS: 32477-35-3 EC Number: 251-063-8 Formula: C7H3F7N2O Molecular Weight: 264.10
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds.
    In Stock Item #: H121494
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    Technical Identifiers
    IUPAC Name
    2,2,3,3,4,4,4-heptafluoro-1-imidazol-1-ylbutan-1-one
    SMILES
    C1=CN(C=N1)C(=O)C(C(C(F)(F)F)(F)F)(F)F
    InChIKey
    MSYHGYDAVLDKCE-UHFFFAOYSA-N
    InChI
    1S/C7H3F7N2O/c8-5(9,6(10,11)7(12,13)14)4(17)16-2-1-15-3-16/h1-3H
    Synonyms
    1-(Heptafluorobutyryl)imidazole | 1-(Perfluorobutyryl)imidazole | NSC 151966
  12. N-Methyl-bis(trifluoroacetamide)
    CAS: 685-27-8 EC Number: 211-680-5 Formula: C5H3F6NO2 Molecular Weight: 223.07
    for GC derivatization ? GC-derivatization grade — reagents to make analytes GC-amenable (volatile/stable). Use before GC to derivatize polar or thermally labile compounds. ≥98%
    In Stock Item #: M121490
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    Technical Identifiers
    IUPAC Name
    2,2,2-trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)acetamide
    SMILES
    CN(C(=O)C(F)(F)F)C(=O)C(F)(F)F
    InChIKey
    AWGBWLXGUPTXHF-UHFFFAOYSA-N
    InChI
    1S/C5H3F6NO2/c1-12(2(13)4(6,7)8)3(14)5(9,10)11/h1H3
    Synonyms
    DTXSID00218623 | N-Methylbis(trifluoroacetamide) | N-Methyl-bis(trifluoroacetamide) | AKOS005206965 | D91371 | FT-063...
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Frequently Asked Questions — for GC derivatization

What pack sizes are typically available for for GC derivatization products? +

Liquid products are commonly offered in 500 mL, 1 L, 2.5 L and 4 L glass bottles; solid reagents in 25 g, 100 g and 500 g units. Larger drums and custom packaging (amber, septum-sealed, pre-cleaned) are available on request through the Bulk & Custom Quote workflow.

What does for GC derivatization mean? +

for GC derivatization indicates that the chemical has been purified and tested specifically for use in gas chromatography. Key specifications typically include controlled UV absorbance at common detection wavelengths, low non-volatile residue, controlled moisture content, and verified lot-to-lot consistency. for GC derivatization is used for mobile phases, sample preparation and analytical standards in this workflow.

How does for GC derivatization compare to standard ACS or AR grade? +

ACS and AR grades are general-purpose analytical purity tiers. for GC derivatization adds workflow-specific specifications — particularly UV absorbance cutoffs and impurity profiles that matter for chromatographic detection. Many for GC derivatization solvents also meet ACS or AR specifications, but the reverse is not always true. For routine analytical work outside chromatography, ACS or AR grade is often more economical.

Can I substitute for GC derivatization with a higher-tier grade? +

Yes. Premium grades such as UltraPureChrom™, 'for HPLC plus', or grades dedicated to MS work generally exceed the specifications of standard chromatography grades. Use a higher tier when method sensitivity, regulated workflows, or trace analysis demand it. Switching down to a lower-tier grade is not recommended without method revalidation.

Is for GC derivatization suitable for LC-MS work? +

Standard chromatography grades can support many LC-MS applications, but for trace MS work or methods sensitive to ionic background and metals, dedicated LC-MS or UHPLC-MS grade solvents are recommended. These include additional metal-content testing and lower particulate levels.

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