Factor Xa, CAS No.9002-05-5

CAS: 9002-05-5 Cat. No.: F1445139

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Pre-lyophilization Protein Concentration: See COA

Accession #

P00742

Bioactivity

See COA

Overview

Human Factor Xa is prepared from Human Factor X by activation with Russell’s Viper Venom. This RVV-X is removed after activation. Complete activation is observed by SDS-PAGE. Factor Xa along with cofactor Va, phospholipids and calcium ions, (the prothrombinase complex) catalyzes the rapid conversion of prothrombin to thrombin.

Extinction Coefficient (1%) =11.6

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Specifications

Product Name

Factor Xa, CAS No.9002-05-5

Synonyms

Human Factor Xa Native Protein | Native human Factor Xa | Coagulation Factor Xa, Human Plasma | coagulation factor Xa | prothrombase | prothrombinase | Stuart factor | thrombokinase | Coagulation factor X | F10 | FX | FXA

Grade

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Specifications & Purity

Bioactive,ActiBioPure™,Native,High Performance,EnzymoPure™,from Human plasma; Pre-lyophilization Protein Concentration: See COA

Biochemical and Physiological Mechanisms

Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting (PubMed:22409427, PubMed:39880037).Factor Xa activates pro-inflammatory signaling pathways i

Bioactivity

See COA

Accession #

P00742

Predicted molecular weight

46 kDa

CAS

9002-05-5

Enzyme Commission Number

EC 3.4.21.6

Molecule Type

Enzyme

Product Line

Biological Products

Storage and Shipping

Concentration

from Human plasma; Pre-lyophilization Protein Concentration: See COA

Reconstitution

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Storage

Store at 2-8°C

Shipped In

Wet ice

Stability And Storage

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.

Frequently Asked Questions

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 9002-05-5.

What is ActiBioPure??

ActiBioPure? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, ActiBioPure? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What does Bioactive mean?

Bioactive indicates that the product has been processed and tested for biological and biochemical applications. Specifications may include endotoxin limits, microbial controls, sterility, low DNase/RNase/protease activity, and verified biological activity where relevant.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.