110 kDa for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 69 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
FITC-dextrans are synthesised by coupling fluoresceinyl isothiocyanate (5-isomer) to selected dextran fractions. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-dextrans from 4 kDa to 2000 kDa. FITC-dextrans are supplied as a yellow to orange powder.
Structure
Dextran is a branched polysaccharide elaborated by the bacteria Leuconostoc mesenteroides B512F. Dextran is essentially a linear glucose chain linked by α-D-(1 – 6) linkages. The degree of branching is about 5 %. The fluorescein moiety is attached by a stable thiocarbamoyl linkage and the labelling procedure does not lead to any depolymerization of the dextran. FITC-dextrans have from 0.002-0.008 mol FITC per glucose unit. These low levels of substitution confer minimal charges to dextran, which is an essential requirement for permeability studies.
Spectral data
FITC-dextran has an excitation maximum of 493 nm and an emission maximum of 518 nm. Maximal intensity is observed at pH >8.
Application
FITC-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more.If you need larger quantities please contact us for a bulk quotation.
| Excitation and Emision Ranges | 493 nm and 518 nm |
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| WGK Germany | 3 |
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Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2313245 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| B2313246 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| B2313247 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| B2313249 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| C2527204 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| Solubility | dissolves readily in water H2O: 25 mg/mL |
|---|---|
| Sensitivity | Light & Heat & Moisture Sensitive |
