Glycyl-L-glutamine hydrate - ≥97%(HPLC) , CAS No.172669-64-6

CAS: 172669-64-6 Cat. No.: G167882 Molecular Weight: 221.21

GRADE & PURITY ≥97%(HPLC)

Synonyms

BCP13679 | UNII-668A00JUHO | (S)-5-Amino-2-(2-aminoacetamido)-5-oxopentanoic acid hydrate | AC-4720 | Glycyl-L-glutamine hydrate | Gly-gln | Glycyl-L-Glutamine (hydrate) | Glycyl-L-glutamine xhydrate | Glycyl-L-glutamine monohydrate | L-Glutamine, N2-glyc

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Glycyl-glutamine (gly-gln) is a dipeptide that is used as a substitute for glutamine in cell culture. Higher cell yields are obtained when this dipeptide is used instead of glutamine, where gly-gln affects substrate utilization and metabolism. Cell growth is higher as the concentrations of this dipeptide remain high, due to lower peptidase affinity.

Heat-stable substitute for glutamine in mammalian cell culture media.

Specifications

Synonyms

BCP13679 | UNII-668A00JUHO | (S)-5-Amino-2-(2-aminoacetamido)-5-oxopentanoic acid hydrate | AC-4720 | Glycyl-L-glutamine hydrate | Gly-gln | Glycyl-L-Glutamine (hydrate) | Glycyl-L-glutamine xhydrate | Glycyl-L-glutamine monohydrate | L-Glutamine, N2-glyc

Specifications & Purity

≥97%(HPLC)

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%(HPLC)

Names and Identifiers

• Pubchem Sid: 504769842
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504769842
• Canonical Smiles: O.NCC(=O)N[C@@H](CCC(N)=O)C(O)=O
• IUPAC Name: (2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoic acid;hydrate
• InChIKey: KLFWVRQACSYLOH-WCCKRBBISA-N
• INCHI: 1S/C7H13N3O4.H2O/c8-3-6(12)10-4(7(13)14)1-2-5(9)11;/h4H,1-3,8H2,(H2,9,11)(H,10,12)(H,13,14);1H2/t4-;/m0./s1
• Isomeric SMILES: C(CC(=O)N)[C@@H](C(=O)O)NC(=O)CN.O
• Alternate CAS: 13115-71-4
• Molecular Weight: 221.21
• Reaxy-Rn: 7395534
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7395534&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: Glutamine and derivatives N-acyl-L-glutamines Alpha amino acid amides Fatty amides Fatty acids and conjugates Secondary carboxylic acid amides Primary carboxylic acid amides Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-dipeptide - Glutamine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - N-acyl-l-glutamine - Alpha-amino acid amide - Alpha-amino acid or derivatives - Fatty acyl - Fatty acid - Fatty amide - Amino acid - Carboxamide group - Secondary carboxylic acid amide - Primary carboxylic acid amide - Amino acid or derivatives - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Organonitrogen compound - Primary aliphatic amine - Organooxygen compound - Primary amine - Hydrocarbon derivative - Carbonyl group - Organic oxide - Amine - Organic oxygen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Specific Rotation[α]: -5.0 to -8.0 deg(C=3, 1mol/L HCl)
• Molecular Weight: 221.210 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 221.101 Da
• Monoisotopic Mass: 221.101 Da
• Topological Polar Surface Area: 137.000 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 241.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3