Glycitein - analytical standard, ≥97% , CAS No.40957-83-3

CAS: 40957-83-3 Cat. No.: G101664 Molecular Weight: 284.26
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥97%
Synonyms
4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy- | s9107 | UNII-92M5F28TVF | 4-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one | 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one | 7,4'-Dihydroxy-6-methoxyisoflavone | Q-100465 |
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Status
Price
Qty
20mg
G101664-20mg
1
$113.90
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Why this grade

analytical standard, ≥97% Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Glycitein is a soy isoflavone used to study apoptosis and antioxidant

Specifications

Synonyms
4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy- | s9107 | UNII-92M5F28TVF | 4-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one | 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one | 7, 4'-Dihydroxy-6-methoxyisoflavone | Q-100465 |
Specifications & Purity
analytical standard, ≥97%
Biochemical and Physiological Mechanisms
Compared to other soy isoflavones, genistein has weaker estrogenic activity. Glycitin is a type of soybean (yellow soybean) isoflavone, and its natural glycoside derivative can synergistically induce specific gene expression with genistein. Soy yellow pig
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Analytical standard
Purity
≥97%
Names and Identifiers
Canonical SmilesCOC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O
IUPAC Name7-hydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one
InChIKeyDXYUAIFZCFRPTH-UHFFFAOYSA-N
INCHI1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
Isomeric SMILES COC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O
WGK Germany 3
Molecular Weight 284.26
Reaxy-Rn 1351032
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1351032&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClassIsoflavonoids
SubclassIsoflav-2-enes
Intermediate Tree Nodes Not available
Direct ParentIsoflavones
Alternative Parents Hydroxyisoflavonoids  Chromones  Anisoles  Pyranones and derivatives  Alkyl aryl ethers  1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Heteroaromatic compounds  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Hydroxyisoflavonoid - Isoflavone - Chromone - Benzopyran - 1-benzopyran - Anisole - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Phenol - Pyranone - Monocyclic benzene moiety - Benzenoid - Pyran - Heteroaromatic compound - Oxacycle - Ether - Organoheterocyclic compound - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as isoflavones. These are polycyclic compounds containing a 2-isoflavene skeleton which bears a ketone group at the C4 carbon atom.
External Descriptors Isoflavonoids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Gusb Beta-glucuronidase (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Giardia intestinalis (1290 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Melan-a (81 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
H2528253Certificate of AnalysisMay 12, 2025 G101664
G2315697Certificate of AnalysisApr 08, 2025 G101664
L2215558Certificate of AnalysisSep 06, 2024 G101664
L2212225Certificate of AnalysisNov 03, 2022 G101664
C2215330Certificate of AnalysisFeb 23, 2022 G101664
Chemical and Physical Properties
Molecular Weight284.260 g/mol
XLogP32.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass284.068 Da
Monoisotopic Mass284.068 Da
Topological Polar Surface Area76.000 Ų
Heavy Atom Count21
Formal Charge0
Complexity424.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Jie Chen, Yishu Ni, Pingjing Zhang, Xianrui Liang, Sheng Fang.  (2022)  Acidic natural deep eutectic solvents as dual solvents and catalysts for the solubilization and deglycosylation of soybean isoflavone extracts: Genistin as a model compound.  FOOD CHEMISTRY,      [PMID:36459802] [10.1016/j.foodchem.2022.134999]
2. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074).  [PMID:35404372] [10.1039/D1FO03816H]
3. Lei Du, Kum-Song Ro, Yiji Zhang, Ya-Jie Tang, Wanbang Li, Jingli Xie, Dongzhi Wei.  (2021)  Effects of lactiplantibacillus plantarum X7021 on physicochemical properties, purines, isoflavones and volatile compounds of fermented soymilk.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2021.12.028]
4. Yajing Fang, Fuqiang Liang, Mengmeng Xia, Weiwei Cao, Siyi Pan, Ting Wu, Xiaoyun Xu.  (2021)  Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells.  FOOD AND CHEMICAL TOXICOLOGY,      [PMID:34217736] [10.1016/j.fct.2021.112381]
5. Liuying Zhu, Wenting Li, Zeyuan Deng, Hongyan Li, Bing Zhang.  (2020)  The Composition and Antioxidant Activity of Bound Phenolics in Three Legumes, and Their Metabolism and Bioaccessibility of Gastrointestinal Tract.  Foods,  (12): (1816).  [PMID:33297502] [10.3390/foods9121816]
6. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song.  (2020)  Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:32480277] [10.1016/j.saa.2020.118519]
7. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang.  (2020)  Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations.  FOOD CHEMISTRY,      [PMID:32330646] [10.1016/j.foodchem.2020.126807]
8. Xianli Gao, Ermeng Liu, Junke Zhang, Mingquan Yang, Sui Chen, Zhan Liu, Haile Ma, Feng Hu.  (2019)  Effects of sonication during moromi fermentation on antioxidant activities of compounds in raw soy sauce.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2019.108605]
9. Xiaonan Zhang, Hongwei Zhang, Xinghao Xia, Nan Pu, Zhuping Yu, Mourtada Nabih, Ying Zhu, Shuang Zhang, Lianzhou Jiang.  (2019)  Preparation and physicochemical characterization of soy isoflavone (SIF) nanoparticles by a liquid antisolvent precipitation method.  ADVANCED POWDER TECHNOLOGY,      [PMID:] [10.1016/j.apt.2019.04.030]
10. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang.  (2017)  Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr).  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2017.03.003]
11. Mian Wang, Yiting Wang, Muhammad Bilal, Chong Xie, Pei Wang, Xin Rui, Runqiang Yang.  (2024)  UV-B Radiation Exhibited Tissue-Specific Regulation of Isoflavone Biosynthesis in Soybean Cell Suspension Cultures.  Foods,  13  (15): (2385).  [PMID:39123575] [10.3390/foods13152385]
12. Hui Cao, Xiaojuan Liu, Nataša Poklar Ulrih, Pradeep K. Sengupta, Jianbo Xiao.  (2018)  Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach.  FOOD CHEMISTRY,      [PMID:30174044] [10.1016/j.foodchem.2018.07.111]
13. Wang Yue, Tang Xiaohan, Zhao Huarong, Pan Yue, Zhang Dingnan, Liu He, Zhu Danshi.  (2026)  Effects of monascus -fermented soybean powder on the quality, isoflavones composition and sensory acceptance of steamed bread.  JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE,      [PMID:] [10.1007/s13197-026-06557-3]
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