Hyaluronidase used for Hyaluronidase from Streptomyces hyalurolyticus has been used: in the preparation of DMEM/F-12 (Dulbecco′s modified eagle medium/nutrient mixture F-12) media for the isolation and purification of single cells from dissociated tumour

CAS: 37259-53-3 Cat. No.: H298749 EC Number: 253-430-8
AVAILABLE TO ORDER
GRADE & PURITY EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. from Streptomyces hyalurolyticus; ≥300 U/vial
Application
Hyaluronidase from Streptomyces hyalurolyticus has been used: in the preparation of DMEM/F-12 (Dulbecco′s modified eagle medium/nutrient mixture F-12) media for the isolation and purification of single cells from dissociated tumour tissue; as a component
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Size
USA
Germany (EU)*
Price
Qty
H298749-300UN
Made to order · 8–12 wks
$999.90
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Why this grade

EnzymoPure™, from Streptomyces hyalurolyticus; ≥300 U/vial EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 55 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Hyaluronidase is widely present in nature. In humans, it is present in a number of organs and body fluids. Hyaluronidase is found in the secretions of virus, bacteriophage, fungi and bacteria. It is also present in nematode and leeches secretions. Snakes and scorpions produce hyaluronidase in their venom. Hyaluronidase is also secreted by bees, spiders, wasps, hornets, caterpillars, fishes and lizards. Hyaluronidase is an endoglycosidase and performs its function along with exoglycosidases, like β-glucuronidase and β-N-acetyl glucosaminidase. Hyaluronidase regulates the hyaluronic acid turnover. Hyaluronate lyase cleaves hyaluronic acid at the β-D-GlcNAc-(1→4)-β-D-GlcA bond, yielding 3-(4-deoxy-β-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine tetra- and hexasaccharides. Unlike other hyaluronidases, this enzyme is specific for hyaluronic acid and is inactive with chondroitin and chondroitin sulfate.

Specifications

Product Name
Hyaluronidase used for Hyaluronidase from Streptomyces hyalurolyticus has been used: in the preparation of DMEM/F-12 (Dulbecco′s modified eagle medium/nutrient mixture F-12) media for the isolation and purification of single cells from dissociated tumour
Synonyms
Hyaluronate Lyase
Grade
EnzymoPure™
Specifications & Purity
EnzymoPure™, from Streptomyces hyalurolyticus; ≥300 U/vial
CAS
37259-53-3
Enzyme Commission Number
4.2.2.1 (BRENDA, IUBMB)
Molecule Type
Enzyme
Storage and Shipping
Application
Hyaluronidase from Streptomyces hyalurolyticus has been used: in the preparation of DMEM/F-12 (Dulbecco′s modified eagle medium/nutrient mixture F-12) media for the isolation and purification of single cells from dissociated tumour tissue; as a component
Concentration
from Streptomyces hyalurolyticus; ≥300 U/vial
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Unit definition
One unit will degrade 0.75μg of the polysaccharide hyaluronic acid per minute at pH 5.35 at 37 °C (as measured by turbidimetric absorbance (λ: 600nm) when complexed with BSA after 45 minutes).

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
G2613674Certificate of AnalysisJul 06, 2026 H298749
K2105267Certificate of AnalysisAug 12, 2025 H298749
H2231488Certificate of AnalysisJul 29, 2022 H298749
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