ι-Carrageenan - Purifed , CAS No.9062-07-1

CAS: 9062-07-1 Cat. No.: C120988 EC Number: 232-949-3 PubChem CID: 11966245

GRADE & PURITY Purifed

Synonyms

[(2R,3R,4R,5R,6S)-4,5-dihydroxy-6-[[(1R,3R,4R,5S,8S)-3-[(2R,3S,4R,5R,6S)-5-hydroxy-2-(hydroxymethyl)-6-[[(1R,3S,4R,5S,8S)-3-hydroxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-3-sulfonatooxyoxan-4-yl]oxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]oct

Storage

Room temperature

Shipped In

Normal

Overview

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.
Carrageenans are linear sulfated (IOTA, KAPA and GAMMA) glycans used as plant defense eliciting and anti-viral agents. Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. IOTA, KAPA and GAMMA carrageenans vary at the level of sulfation and may be studied comparatively to determine their differential protective, antiviral and immunosuppression activities.

Specifications

Synonyms

[(2R, 3R, 4R, 5R, 6S)-4, 5-dihydroxy-6-[[(1R, 3R, 4R, 5S, 8S)-3-[(2R, 3S, 4R, 5R, 6S)-5-hydroxy-2-(hydroxymethyl)-6-[[(1R, 3S, 4R, 5S, 8S)-3-hydroxy-4-sulfonatooxy-2, 6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-3-sulfonatooxyoxan-4-yl]oxy-4-sulfonatooxy-2, 6-dioxabicyclo[3.2.1]oct

Specifications & Purity

Purifed

Storage

Room temperature

Shipped In

Normal

Grade

Purifed

Names and Identifiers

• Pubchem Sid: 488197819
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488197819
• Canonical Smiles: C1C2C(C(O1)C(C(O2)O)OS(=O)(=O)[O-])OC3C(C(C(C(O3)CO)OS(=O)(=O)[O-])OC4C(C5C(C(O4)CO5)OC6C(C(C(C(O6)CO)OS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])O
• IUPAC Name: [(2R,3R,4R,5R,6S)-4,5-dihydroxy-6-[[(1R,3R,4R,5S,8S)-3-[(2R,3S,4R,5R,6S)-5-hydroxy-2-(hydroxymethyl)-6-[[(1R,3S,4R,5S,8S)-3-hydroxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-3-sulfonatooxyoxan-4-yl]oxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-2-(hydroxymethyl)oxan-3-yl] sulfate
• InChIKey: QIDSWKFAPCTSKL-RRQHLKGPSA-J
• INCHI: 1S/C24H38O31S4/c25-1-5-12(52-56(31,32)33)9(27)10(28)22(46-5)49-14-8-4-44-18(14)20(55-59(40,41)42)24(48-8)51-16-11(29)23(47-6(2-26)15(16)53-57(34,35)36)50-13-7-3-43-17(13)19(21(30)45-7)54-58(37,38)39/h5-30H,1-4H2,(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)/p-4/t5-,6-,7-,8-,9-,10-,11-,12+,13+,14+,15+,16-,17+,18+,19-,20-,21+,22+,23+,24-/m1/s1
• Isomeric SMILES: C1[C@@H]2[C@@H]([C@H](O1)[C@H]([C@H](O2)O)OS(=O)(=O)[O-])O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)OS(=O)(=O)[O-])O[C@@H]4[C@@H]([C@@H]5[C@H]([C@H](O4)CO5)O[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)CO)OS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])O
• WGK Germany: 2
• PubChem CID: 11966245

Chemical and Physical Properties

• Solubility: artially soluble in water, Soluble in hot water. Insoluble in ethanol, in hot concentrated salt solutions.

References

1. Lingjun Zeng, Bo Liu, Lijie Duan, Guanghui Gao.  (2023)  Tough, recyclable and biocompatible carrageenan-modified polyvinyl alcohol ionic hydrogel with physical cross-linked for multimodal sensing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37734518] [10.1016/j.ijbiomac.2023.126954]

2. Jie Tian, Nan Wang, Wenxiu Teng, Shuang Song, Jie Pang, Chunhua Wu, Chengrong Wen.  (2023)  Effects of ε-polylysine or ε-polylysine hydrochloride on the pH responsive ι-carrageenan gel.  POLYMER INTERNATIONAL,  72  (8): (720-726).  [PMID:] [10.1002/pi.6530]

3. Yingying Liu, Wenwen Hou, Pengfei Qi, Jie Yang, Xuelai Xie, Min Lin, Yanzhi Xia, Zhihong Nie, Kunyan Sui.  (2022)  Hierarchical nano-helix as a new reinforcing unit for simultaneously ultra-strong and super-tough alginate fibers.  CARBOHYDRATE POLYMERS,      [PMID:36184164] [10.1016/j.carbpol.2022.119998]

4. Xin-Yu Jiang, Jia-Nan Yan, Yi-Nan Du, Shi-Qi Xu, Hai-Tao Wu.  (2021)  Effects of several polysaccharides on rheological properties of scallop (Patinopecten yessoensis) male gonad hydrolysates.  Colloid and Interface Science Communications,      [PMID:] [10.1016/j.colcom.2021.100500]

5. Xiong Li, Shiming Huang, Xi Chen, Qijun Xu, Yongxuan Ma, Lijun You, Viktoryia Kulikouskaya, Jianbo Xiao, Jinhua Piao.  (2020)  Structural characteristic of a sulfated polysaccharide from Gracilaria Lemaneiformis and its lipid metabolism regulation effect.  Food & Function,  11  (12): (10876-10885).  [PMID:33245309] [10.1039/D0FO02575E]

6. Houchao Jing, Jianping Shi, Peipei Guoab, Shuang Guan, Hai Fu, Wei Cui.  (2020)  Hydrogels based on physically cross-linked network with high mechanical property and recasting ability.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2020.125805]

7. Xiong Li, Chuyi Li, Wanzi Yao, Jian Mao.  (2024)  Characterization of three carrageenases from marine bacterium Shewanella sp. LE8: A novel approach for producing ι-carrageenan oligosaccharides.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39725097] [10.1016/j.ijbiomac.2024.138973]

8. Jiale Chai, Xinglian Xu, Xue Zhao.  (2025)  Effects of polysaccharides on the solubilization of myofibrillar protein in aqueous solution: A comparative study.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2025.111193]

9. Li Lanchen, Peng Xuesong, Jiang Jie, Li Ruopeng, Zhang Jinqiu, Yang Peixia, An Maozhong.  (2024)  Functional additives inhibit crystal growth to achieve low-roughness and high-peel strength of micro-coarsening copper foil.  IONICS,  30  (7): (4281-4295).  [PMID:] [10.1007/s11581-024-05566-6]

10. Lingjun Zeng, Jian Wang, Lijie Duan, Guanghui Gao.  (2024)  Highly transparent ionogel for wearable force sensor and 3D printing.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2024.113641]

11. Hao Yan, Junsheng Wang, Cong Du, Zheng Li, Hua Yuan, Zhen Xu, Yeqiang Tan.  (2024)  Hydrogen Bond Mediated Strong Plasticization for High Performance Alginate Plastics.  ADVANCED MATERIALS,      [PMID:38488330] [10.1002/adma.202400648]

12. Xiong Li, Chuyi Li, Yizhou Liu, Gang Han, Congyu Lin, Xiaoli Chen, Jian Mao.  (2024)  Rheological and Structural Characterization of Carrageenans during Depolymerization Conducted by a Marine Bacterium Shewanella sp. LE8.  Gels,  10  (8): (502).  [PMID:39195031] [10.3390/gels10080502]

13. Duoping Yang, Aijing Sun.  (2025)  Solvent induced method for preparation of multi-advantage carrageenan films.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39756724] [10.1016/j.ijbiomac.2025.139478]

14. Liurong Huang, Yuhan Yan, Lulu Qu, Feng Li, Lihong Chen, Yunliang Li.  (2024)  Structure, emulsifying and embedding characteristics of soy protein isolate induced by the complexation of carrageenan with different charge groups.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2024.110455]

15. Benke Cui, Chunguang Ren, Renlong Zhang, Yuhang Ren, Jiaxin Liu, Yanzhe Gou, Tianyu Zhao, Xue Jiang, Hongli Cui, Xiuzhi Wang, Linlin Wang.  (2025)  Chlorella-encapsulated living hydrogel based on gelatin and carrageenan with oxygen production, hemostatic and antibacterial capacity for promoting wound healing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40132716] [10.1016/j.ijbiomac.2025.142356]

16. Hongfei Du, Huang Zhang, Zixin Zhang, Zihan Yuan, Maiquan Li, Lei Zhou, Yan Liu, Aihua Lou, Mei Li, Ye Jiao, Qingwu Shen, Chaoyi Xue, Wei Quan, Lan Mo.  (2025)  Synergistic inhibition of Maillard reaction hazards: Multifunctional hydrocolloids enable healthier air-fried beef patties with reduced heterocyclic amines and AGEs.  FOOD CHEMISTRY,      [PMID:40393229] [10.1016/j.foodchem.2025.144766]

17. Jianzheng Yang, Yan Zhou, Shang Du, Bing Wu, Jianying Zhang, Shanjun Song, Tao Zhou, Jinming Zhang.  (2025)  Superior-Selective and Complete Recycling of Trace Precious Metals From Wastewater by Magnetic Trilayer Carbon-Aerogels.  Advanced Science,      [PMID:40433866] [10.1002/advs.202500858]

18. Zhu-Jun Zhang, Fan-Yu Kong, Lin-Da Zhang, Miao-Miao Luo, Yin-Yin Lv, Ce Wang, Bin Lai, Li-Chao Zhang, Jia-Nan Yan, Hai-Tao Wu.  (2025)  Modification of Spanish Mackerel (Scomberomorus niphonius) Surimi Gels by Three Anionic Polysaccharides.  Foods,  14  (15): (2671).  [PMID:40807608] [10.3390/foods14152671]

19. Xuanyu Liu, Yifan Wu, Yuhang Wu, Shuang Zhai, Ya-nan Zhang.  (2025)  Highly-sensitivity copper(II) ion detection via optical fiber Mach-Zehnder interferometer modified with ZIF-67/ι-carrageenan/sucrose.  OPTICS AND LASER TECHNOLOGY,      [PMID:] [10.1016/j.optlastec.2025.114339]

20. Chunguang Ren, Shuling Zhuang, Tianyu Zhao, Wenshuo Shang, Zhihao Meng, Jiaxin Liu, Yuhang Ren, Xue Jiang, Lingjie Meng, Hong He, Xinyan Gao, Zhonghua Wang, Jingwei Tian, Linlin Wang.  (2026)  All-in-one amoeba-inspired Chlorella-loaded hydrogel integrating adaptive, self-healing, antibacterial, and motion monitoring capabilities for wound healing.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:41689942] [10.1016/j.colsurfb.2026.115553]