(±)-J 113397 - ≥98% , CAS No.217461-40-0

CAS: 217461-40-0 Cat. No.: J287289 Molecular Weight: 399.57 PubChem CID: 90488772

GRADE & PURITY ≥98%

Synonyms

(±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

(±)-1-[(3R*, 4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

(±) - J-113397 is an effective and selective non peptide ORL1 receptor antagonist with a Ki of 1.8 nM against human cloned ORL1. J-113397 inhibits the binding of GTP γ S stimulated by nociceptin/orphan FQ to CHO cells expressing ORL1, with an IC50 value o

Storage

Protected from light, Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CCN1C4=C(C=CC=C4)N([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)C1=O.CCN5C8=C(C=CC=C8)N([C@H]6CCN(CC7CCCCCCC7)C[C@@H]6CO)C5=O
• InChIKey: NLSVMRCGZVSAFK-SDNSQTLOSA-N
• Isomeric SMILES: CCN1C2=CC=CC=C2N(C1=O)[C@@H]3CCN(C[C@H]3CO)CC4CCCCCCC4.CCN1C2=CC=CC=C2N(C1=O)[C@H]3CCN(C[C@@H]3CO)CC4CCCCCCC4
• PubChem CID: 90488772
• Molecular Weight: 399.57

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 19.98, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 19.98, Max Conc. mM: 50
• Sensitivity: Light and Moisture sensitive