L-Cysteine hydrochloride monohydrate - Animal Free, PharmPure™, USP, Ph.Eur., for cell culture , CAS No.7048-04-6

CAS: 7048-04-6 Cat. No.: C118575 Molecular Weight: 175.63 Beilstein Registry Number: 5158059 EC Number: 615-117-8 PubChem CID: 23462
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. PharmPure™ ? PharmPure™ — Aladdin's line of biopharmaceutical raw and starting materials. Use for pharma manufacturing inputs needing high purity and documentation. USP ? United States Pharmacopeia grade — meets USP monograph specs for pharmaceutical use. Use for drug manufacturing, QC, and applications requiring US compendial compliance. Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements.
Synonyms
L-Cysteine monohydrate monochloride | L-CYSTEINE, HYDROCHLORIDE, MONOHYDRATE | Cysteine hydrochloride monohydrate, European Pharmacopoeia (EP) Reference Standard | L-Cysteine (hydrochloride hydrate) | L-Cysteine hydrochloride monohydrate, USP grade | H-Cy
Storage
Protected from light,Argon charged,Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100g
C118575-100g
1
$58.90
500g
C118575-500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Animal Free, PharmPure™, USP, Ph.Eur., for cell culture Animal Free,for Cell culture,Ph.Eur.,PharmPure™,USP for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 36 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
L-Cysteine monohydrate monochloride | L-CYSTEINE, HYDROCHLORIDE, MONOHYDRATE | Cysteine hydrochloride monohydrate, European Pharmacopoeia (EP) Reference Standard | L-Cysteine (hydrochloride hydrate) | L-Cysteine hydrochloride monohydrate, USP grade | H-Cy
Specifications & Purity
Animal Free, PharmPure™, USP, Ph.Eur., for cell culture
Storage
Protected from light, Argon charged, Room temperature
Shipped In
Normal
Grade
Animal Free, for Cell culture, Ph.Eur., PharmPure™, USP
Names and Identifiers
Canonical SmilesO.Cl.N[C@@H](CS)C(O)=O
IUPAC Name(2R)-2-amino-3-sulfanylpropanoic acid;hydrate;hydrochloride
InChIKeyQIJRTFXNRTXDIP-JIZZDEOASA-N
INCHI1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1
Isomeric SMILES C([C@@H](C(=O)O)N)S.O.Cl
WGK Germany 3
Alternate CAS 345909-32-2
PubChem CID 23462
Molecular Weight 175.63
Beilstein 5158059

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentCysteine and derivatives
Alternative Parents L-alpha-amino acids  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Alkylthiols  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrochlorides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Cysteine or derivatives - Alpha-amino acid - L-alpha-amino acid - Amino acid - Alkylthiol - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxygen compound - Hydrochloride - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as cysteine and derivatives. These are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

19 results found

Lot NumberCertificate TypeDateItem
A2613002Certificate of AnalysisDec 03, 2025 C118575
A2613003Certificate of AnalysisDec 03, 2025 C118575
A2613001Certificate of AnalysisDec 03, 2025 C118575
H2511026Certificate of AnalysisFeb 13, 2025 C118575
D2503349Certificate of AnalysisFeb 13, 2025 C118575
D2503356Certificate of AnalysisFeb 13, 2025 C118575
D2503420Certificate of AnalysisFeb 13, 2025 C118575
K2408119Certificate of AnalysisApr 08, 2024 C118575
G2415172Certificate of AnalysisApr 08, 2024 C118575
G2415171Certificate of AnalysisApr 08, 2024 C118575
G2415170Certificate of AnalysisApr 08, 2024 C118575
G2415169Certificate of AnalysisApr 08, 2024 C118575
G2415168Certificate of AnalysisApr 08, 2024 C118575
F2228157Certificate of AnalysisMay 31, 2022 C118575
F2228156Certificate of AnalysisMay 31, 2022 C118575
F2228147Certificate of AnalysisMay 31, 2022 C118575
D2324143Certificate of AnalysisMay 31, 2022 C118575
I2321023Certificate of AnalysisMay 31, 2022 C118575
D23111118Certificate of AnalysisMay 31, 2022 C118575

Show more ⌵

Chemical and Physical Properties
Sensitivitylight、air、moisture sensitive
Molecular Weight175.640 g/mol
XLogP3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass175.007 Da
Monoisotopic Mass175.007 Da
Topological Polar Surface Area65.300 Ų
Heavy Atom Count9
Formal Charge0
Complexity75.300
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count3
Documents & Articles
Citations of This Product
References
1. Haixia Lyu, Wenzhang Zhu, Kaixuan Chen, Jun Gao, Zenghong Xie.  (2023)  3D flower-shaped g-C3N4/MoS2 composite with structure defect for synergistic degradation of dyes.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2023.104656]
2. Ya Luo, Zhao Ma, Cristabelle De Souza, Shaolei Wang, Fengzhi Qiao, Huaxi Yi, Pimin Gong, Zhe Zhang, Tongjie Liu, Lanwei Zhang, Kai Lin.  (2023)  Microfluidic fabrication of encapsulated probiotic microspheres using cysteine-modified chitosan with dual functions of bacterial adhesion and intestinal mucosal adhesion.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2023.109602]
3. Wenliang Liu, Xiaohan Li, Yuqi Wang, Debo Yang, Zongzhen Guo, Mengfei Liu, Jiqian Wang.  (2023)  Multi-branched AgAuPt nanoparticles for efficient electrocatalytic hydrogen evolution: Synergism of tip-enhanced electric field effect and local electric field effect.  Journal of Energy Chemistry,      [PMID:] [10.1016/j.jechem.2023.02.032]
4. Qinming Xu, Xing Li, Jingang Yang, Yan Zhang, Xiaocui Deng, Gang Li, Qingmei Yuan.  (2023)  Naphthyl-Poly(S-((2-carboxyethyl)thio)-l-cysteine) Peptide Amphiphiles with Different Degrees of Polymerization: Synthesis, Self-Assembly, pH/Reduction-Triggered Drug Release, and Cytotoxicity.  MOLECULAR PHARMACEUTICS,      [PMID:36648435] [10.1021/acs.molpharmaceut.2c00925]
5. Hongying Li, Jiale Zhang, Lingling Jiang, Ruo Yuan, Xia Yang.  (2022)  Chiral plasmonic Au–Ag core shell nanobipyramid for SERS enantiomeric discrimination of biologically relevant small molecules.  ANALYTICA CHIMICA ACTA,      [PMID:36628734] [10.1016/j.aca.2022.340740]
6. Wenliang Liu, Yan Wang, Yuqi Wang, Xiaohan Li, Kai Qi, Jiqian Wang, Hai Xu.  (2022)  Black Silver Nanocubes@Amino Acid-Encoded Highly Branched Gold Shells with Efficient Photothermal Conversion for Tumor Therapy.  ACS Applied Materials & Interfaces,      [PMID:36538335] [10.1021/acsami.2c14436]
7. Fang Fang, Yuxin He, Jutang Zhao, Yanli Zhang, Chunhua Chen, Huijun He, Quanyong Wu, Mengwei Hu, Shaoping Nie, Mingyong Xie, Jielun Hu.  (2022)  Effects of boiling and steaming process on dietary fiber components and in vitro fermentation characteristics of 9 kinds of whole grains.  FOOD RESEARCH INTERNATIONAL,      [PMID:36737921] [10.1016/j.foodres.2022.112328]
8. Dan Zhao, Mengyu Xu, Kang Dai, Huan Liu, Yan Jiao, Xincai Xiao.  (2022)  The preparation of chiral carbon dots and the study on their antibacterial abilities.  MATERIALS CHEMISTRY AND PHYSICS,      [PMID:] [10.1016/j.matchemphys.2022.127144]
9. Baimanov Didar, Wang Jing, Zhang Jun, Liu Ke, Cong Yalin, Shi Xiaomeng, Zhang Xiaohui, Li Yufeng, Li Xiumin, Qiao Rongrong, Zhao Yuliang, Zhou Yunlong, Wang Liming, Chen Chunying.  (2022)  In situ analysis of nanoparticle soft corona and dynamic evolution.  Nature Communications,  13  (1): (1-14).  [PMID:36104325] [10.1038/s41467-022-33044-y]
10. Lingkai Zhu, Yuyuan Yao, Dingzhou Chen, Ping Lan.  (2022)  The effective removal of Pb2+ by activated carbon fibers modified by L-cysteine: exploration of kinetics, thermodynamics and mechanism.  RSC Advances,  12  (31): (20062-20073).  [PMID:35919620] [10.1039/D2RA01521H]
11. Saheed Abiola Raheem, Hangjia Shen, Ali Saad, Haichuan Guo, Tiju Thomas, Minghui Yang.  (2022)  Mo3N2/VO2 composite as electrocatalysts for hydrogen evolution reaction.  INORGANIC CHEMISTRY COMMUNICATIONS,      [PMID:] [10.1016/j.inoche.2022.109614]
12. Junjie Hao, Junzi Li, Meijuan Chen, Xijian Duan, Bing Xu, Yiwen Li, Tingchao He, Xiao Wei Sun, Marie-Hélène Delville, Jiaji Cheng.  (2022)  The mechanism of ligand-induced chiral transmission through a top-down selective domain etching process.  Materials Chemistry Frontiers,  (9): (1194-1208).  [PMID:] [10.1039/D2QM00075J]
13. Jun Zhang, Tingyang Xing, Min Zhang, Yunlong Zhou.  (2022)  Facile preparation of Cu2-xS supernanoparticles with an unambiguous SERS enhancement mechanism.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2021.134457]
14. Bailiang Wang, Liyang Zhou, Yishun Guo, Hanwen Guo, Yiming Zhong, Xiaomin Huang, Yifan Ge, Qingying Wang, Xiaoying Chu, Yingying Jin, Kaiyue Lan, Mei Yang, Jia Qu.  (2021)  Cyanobacteria-based self-oxygenated photodynamic therapy for anaerobic infection treatment and tissue repair.  Bioactive Materials,      [PMID:35128179] [10.1016/j.bioactmat.2021.10.032]
15. Junjie Hao, Fenghuan Zhao, Qiushi Wang, Jiaying Lin, Peixian Chen, Junzi Li, Dongxiang Zhang, Meijuan Chen, Peizhao Liu, Marie-Helene Delville, Tingchao He, Jiaji Cheng, Yiwen Li.  (2021)  Optically Active CdSe/CdS Nanoplatelets Exhibiting Both Circular Dichroism and Circularly Polarized Luminescence.  Advanced Optical Materials,  (20): (2101142).  [PMID:] [10.1002/adom.202101142]
16. Chengyi Xie, Liancheng Gu, Qidi Wu, Lei Li, Chenlu Wang, Jiancheng Yu, Keqi Tang.  (2020)  Effective Chiral Discrimination of Amino Acids through Oligosaccharide Incorporation by Trapped Ion Mobility Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:33226780] [10.1021/acs.analchem.0c03461]
17. Rui Li, Jinhu Wang, Yi He, Faqin Dong, Liang Bian, Bowen Li.  (2019)  Mechanochemical Synthesis of Defective Molybdenum Trioxide, Titanium Dioxide, and Zinc Oxide at Room Temperature.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.9b00374]
18. Xiongbin Wang, Junjie Hao, Jiaji Cheng, Junzi Li, Jun Miao, Ruxue Li, Yiwen Li, Jiagen Li, Yuhui Liu, Xi Zhu, Yanjun Liu, Xiao Wei Sun, Zikang Tang, Marie-Hélène Delville, Tingchao He, Rui Chen.  (2019)  Chiral CdSe nanoplatelets as an ultrasensitive probe for lead ion sensing.  Nanoscale,  11  (19): (9327-9334).  [PMID:30911741] [10.1039/C8NR10506E]
19. Kai Zhang, Chaoyan Lou, Yan Zhu, Mingyu Zhi, Xiuqiong Zeng.  (2018)  Hyperbranched anion exchangers prepared from thiol-ene modified polymeric substrates for suppressed ion chromatography.  TALANTA,      [PMID:29674073] [10.1016/j.talanta.2018.03.046]
20. Chun Chen, Qiang Huang, Xiong Fu, Rui Hai Liu.  (2016)  In vitro fermentation of mulberry fruit polysaccharides by human fecal inocula and impact on microbiota.  Food & Function,  (11): (4637-4643).  [PMID:27748781] [10.1039/C6FO01248E]
21. Shuxin Wang, Chenxia Guan, Pu Wang, Donghui Wang, Hanqi Wang, Ryan Chak Sang Yip, Hao Chen.  (2024)  A thiolated oxidized guar gum and sodium alginate dual-network microspheres with enhanced gastric acid resistance and mucoadhesion for delivery of probiotics.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38945718] [10.1016/j.ijbiomac.2024.133395]
22. Jun Zhang, Kai Wu, Xiaoqing Gao, Min Zhang, Xin Zhou, Florian Bertram, Chen Shen, Yunlong Zhou.  (2024)  Achiral and chiral ligands synergistically harness chiral self-assembly of inorganics.  Science Advances,  10  (42):   [PMID:39423258] [10.1126/sciadv.ado5948]
23. Wenliang Liu, Xiaoyu Fang, Xinfeng Ju, Kang Gao, Dong Wang, Hai Xu, Jiqian Wang.  (2024)  Amino acid-induced synthesis of chiral AgAuPt nanoparticles with branched structure for circularly polarized enantioselective photoelectrocatalytic water splitting.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:38964126] [10.1016/j.jcis.2024.07.001]
24. Mingzhao Jiang, Xinyi Xu, Siyu Liu, Liu Liu, Xuemei Wang, Hui Jiang.  (2024)  Enhancement of nanozyme activity by second ligand modification on glutathione protected gold nanoclusters for regulation of intracellular oxidative stress.  INORGANIC CHEMISTRY COMMUNICATIONS,      [PMID:] [10.1016/j.inoche.2024.112115]
25. Yuanyuan Zhao, Pan Wang, Dan Wang, Wenting Zhao, Junjuan Wang, Zhiwen Ge, Ye Liu, Xiaoyan Zhao.  (2025)  Gut microbiota and metabolic profile affected by pectic domains during in vitro rat fecal fermentation: A comparative study between different glycans rich in pectic monosaccharides.  CARBOHYDRATE POLYMERS,      [PMID:40049951] [10.1016/j.carbpol.2025.123365]
26. Fang Fang, Yu-Xin He, Hao-Qiang Wang, Yan-Li Zhang, Ya-dong Zhong, Xiao-Tian Hu, Shao-Ping Nie, Ming-Yong Xie, Jie-Lun Hu.  (2024)  Impact of eight extruded starchy whole grains on glycemic regulation and fecal microbiota modulation.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2024.110756]
27. Luzhan Huang, Yongchao Jiang, Pengcheng Zhang, Muhan Li, Bingrong Liu, Keyong Tang.  (2024)  Injectable Modified Sodium Alginate Microspheres for Enhanced Operative Efficiency and Safety in Endoscopic Submucosal Dissection.  BIOMACROMOLECULES,      [PMID:38652682] [10.1021/acs.biomac.4c00081]
28. Qinglian Wu, Lin Deng, Tian Lan, Hui Wang, Kaiming Wang, Huacheng Zhu, Yanping Zhou, Wanqian Guo.  (2024)  Outstanding enhancement of caproate production with microwave pyrolyzed highly reductive biochar addition.  BIORESOURCE TECHNOLOGY,      [PMID:39284373] [10.1016/j.biortech.2024.131457]
29. Shuai Guo, Shun Yao, Huanchun Xing, Wenbin Cao, Jianyu Wang, Xinran Zhao, Yajing Wei, Ruizhi Lin, Xin Sui, Yuan Luo, Jun Deng, Jun Yang, Yongan Wang.  (2024)  Photothermal-enhanced detoxification metal-organic framework microneedle array for 2-chloroethyl ethyl sulfide-poisoned wound healing.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2024.113286]
30. Yilan An, Zheng Zhong, Chuang Guo, Weiwei Cui, Ming Gao, Dongbo Guan, Yanli Dou.  (2024)  Physically crosslinked hydrogel based on silver nanowires with a discontinuous rigid framework for robust, sensitive, antibacterial, and biocompatible flexible sensors.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2024.135641]
31. Yu Sun, Yushuang Shang, Xinyu Zhang, Zhaoyan Ge, Fengni Liu, Jian Shen, Jiang Yuan.  (2025)  Synthesis of a Novel DMSP-Typed Zwitterion and Construction on PET Surface via Surface-Initiated RAFT Method.  BIOMACROMOLECULES,      [PMID:40059646] [10.1021/acs.biomac.4c01470]
32. Fengzhi Qiao, Ya Luo, Peng Lei, Shaolei Wang, Zhi Duan, Hongchang Cui, Tongjie Liu, Huaxi Yi, Cristabelle De Souza, Guanhua Xuan, Xiangzhao Mao, Zhao Ma, Lanwei Zhang, Kai Lin.  (2025)  Microfluidic Fabrication of Hyaluronic Acid–Cysteine-Modified Chitosan Microspheres for CD44-Targeted Probiotic Delivery in Colitis Treatment.  ACS Applied Materials & Interfaces,      [PMID:40651026] [10.1021/acsami.5c10456]
33. Yongchao Jiang, Jinzhe Xu, Luzhan Huang, Keyong Tang.  (2025)  Injectable multifunctional modified sodium alginate microparticles for rapid hemostasis and wound repair following endoscopic submucosal dissection.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40834960] [10.1016/j.ijbiomac.2025.146966]
34. Junjie Hao, Yiwen Li, Jun Miao, Rulin Liu, Jiagen Li, Haochen Liu, Qiushi Wang, Huan Liu, Marie-Hélène Delville, Tingchao He, Kai Wang, Xi Zhu, Jiaji Cheng.  (2020)  Ligand-Induced Chirality in Asymmetric CdSe/CdS Nanostructures: A Close Look at Chiral Tadpoles.  ACS Nano,      [PMID:32806030] [10.1021/acsnano.0c03909]
35. Jiaji Cheng, Junjie Hao, Haochen Liu, Jiagen Li, Junzi Li, Xi Zhu, Xiaodong Lin, Kai Wang, Tingchao He.  (2018)  Optically Active CdSe-Dot/CdS-Rod Nanocrystals with Induced Chirality and Circularly Polarized Luminescence.  ACS Nano,      [PMID:29791135] [10.1021/acsnano.8b00112]
36. Xiaoli Zhou, Zhicheng Qin, Yan Chen, YaPing Wang, Bin Du, Dong Lin, Lingshuai Meng.  (2025)  Effect of bound polyphenol removal on in vitro digestion and fermentation of Rosa roxburghii Tratt. dietary fiber.  Journal of Agriculture and Food Research,      [PMID:] [10.1016/j.jafr.2025.102542]
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.