L-Homoarginine Hydrochloride - ≥98% , CAS No.1483-01-8

CAS: 1483-01-8 Cat. No.: H100536 Molecular Weight: 224.69 Beilstein Registry Number: 4016621 EC Number: 216-045-6 PubChem CID: 2723930

GRADE & PURITY ≥98%

Synonyms

L-HOMOARGININE HCL | H-HomoArg-OH.HCl | C7H17ClN4O2 | N6-(Aminoiminomethyl)-L-lysine Hydrochloride | L-Homoarginine hydrochloride | H-HomoArg-OH | DTXSID201342617 | AS-12991 | AKOS015924239 | AMY14323 | H1172 | L(+)-Homoarginine hydrochloride | SCHEMBL710

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

L-HOMOARGININE HCL | H-HomoArg-OH.HCl | C7H17ClN4O2 | N6-(Aminoiminomethyl)-L-lysine Hydrochloride | L-Homoarginine hydrochloride | H-HomoArg-OH | DTXSID201342617 | AS-12991 | AKOS015924239 | AMY14323 | H1172 | L(+)-Homoarginine hydrochloride | SCHEMBL710

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Homoarginine is an inhibitor of tissue-specific alkaline phosphatase (TNALP). It is also an inhibitor of arginine cell transport through sodium-independent high affinity y+transporter.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488192222
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488192222
• Canonical Smiles: C(CCN=C(N)N)CC(C(=O)O)N.Cl
• IUPAC Name: (2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid;hydrochloride
• InChIKey: YMKBVNVCKUYUDM-JEDNCBNOSA-N
• INCHI: 1S/C7H16N4O2.ClH/c8-5(6(12)13)3-1-2-4-11-7(9)10;/h5H,1-4,8H2,(H,12,13)(H4,9,10,11);1H/t5-;/m0./s1
• Isomeric SMILES: C(CCN=C(N)N)C[C@@H](C(=O)O)N.Cl
• WGK Germany: 3
• PubChem CID: 2723930
• Molecular Weight: 224.69
• Beilstein: 4016621
• Reaxy-Rn: 4016621

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Medium-chain fatty acids Guanidines Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidamides Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Medium-chain fatty acid - Fatty acid - Fatty acyl - Guanidine - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Carbonyl group - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Amine - Primary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrochloride - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water(50 mg/mL).
• Sensitivity: Moisture sensitive
• Specific Rotation[α]: 18° (C=8.6N,HCl)
• Melt Point(°C): 213-215°C
• Molecular Weight: 224.690 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 224.104 Da
• Monoisotopic Mass: 224.104 Da
• Topological Polar Surface Area: 128.000 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 189.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Chi Yan, Xingyu Chen, Wenqing Gao, Chunlan Tang, Liwen Du, Chengyi Xie, Feng Xu, Keqi Tang, Jiancheng Yu.  (2025)  Chiral Derivatization Enables High-Resolution Ion Mobility Spectrometry of 30 Amino Acid Enantiomers.  ANALYTICAL CHEMISTRY,      [PMID:41451537] [10.1021/acs.analchem.5c06382]