Lithium 2,2,6,6-tetramethylpiperidide(LTMP) - ≥97% , CAS No.38227-87-1

CAS: 38227-87-1 Cat. No.: L469148 Molecular Weight: 147.19 EC Number: 684-475-5

GRADE & PURITY ≥97%

Synonyms

2,2,6,6 tetramethyl-lithio-piperidine | Q1110352 | lithium 2,2,6,6-tetramethyl piperidin-1-ide | lithium;2,2,6,6-tetramethylpiperidin-1-ide | N-lithio 2 | A904616 | AKOS006280823 | lithium tetramethylpiperidide | Lithium 2,2,6,6-tetramethylpiperidide, 97%

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Description

Lithium 2,2,6,6-tetramethylpiperidide is a strong base and can be used:For the synthesis of enamines from terminal epoxides throughtrans-α-lithiated epoxide as an intermediate.For ortholithiation of arenes such as 1,3-bis(trifluoromethyl)benzene, 4,4-dimethyl-2-phenyl-2-oxazoline, 1,4-bis(trifluoromethyl)benzene and 1,3-dimethoxybenzene.In combination with Lewis donor ligand,N,N,N′,N′-tetramethylethylenediamine (TMEDA) for deprotonative metalation of methoxy-substituted arenes.

Specifications

Synonyms

2, 2, 6, 6 tetramethyl-lithio-piperidine | Q1110352 | lithium 2, 2, 6, 6-tetramethyl piperidin-1-ide | lithium;2, 2, 6, 6-tetramethylpiperidin-1-ide | N-lithio 2 | A904616 | AKOS006280823 | lithium tetramethylpiperidide | Lithium 2, 2, 6, 6-tetramethylpiperidide, 97%

Specifications & Purity

≥97%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 504765933
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504765933
• Canonical Smiles: [Li+].CC1(CCCC([N-]1)(C)C)C
• IUPAC Name: lithium;2,2,6,6-tetramethylpiperidin-1-ide
• InChIKey: ANYSGBYRTLOUPO-UHFFFAOYSA-N
• INCHI: 1S/C9H18N.Li/c1-8(2)6-5-7-9(3,4)10-8;/h5-7H2,1-4H3;/q-1;+1
• Isomeric SMILES: [Li+].CC1(CCCC([N-]1)(C)C)C
• WGK Germany: 3
• Molecular Weight: 147.19
• Reaxy-Rn: 3567881
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3567881&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Piperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Piperidines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Piperidines
• Alternative Parents: Organic lithium salts Azacyclic compounds Organonitrogen compounds Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Piperidine - Organic lithium salt - Azacycle - Organic alkali metal salt - Organic nitrogen compound - Hydrocarbon derivative - Organic salt - Organonitrogen compound - Organic cation - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as piperidines. These are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture sensitive
• Molecular Weight: 147.200 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 147.16 Da
• Monoisotopic Mass: 147.16 Da
• Topological Polar Surface Area: 1.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 116.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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