Magnolol - Moligand™, ≥98%(HPLC) , CAS No.528-43-8

Name: Magnolol - Moligand™, ≥98%(HPLC) , CAS No.528-43-8
SKU: M111378
Availability: InStock

CAS: 528-43-8 Cat. No.: M111378 Formula: C₁₈H₁₈O₂ Molecular Weight: 266.33 Beilstein Registry Number: 6(4)6918 EC Number: 610-903-7

37 Citations COA

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Magnolol - Moligand™, ≥98%(HPLC) CAS No(528-43-8) M111378 by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥98%(HPLC)

Synonyms

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product Solution Calculators Reviews Frequently Asked Questions

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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 37 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Bioactive plant component with antifungal, antibacterial and antioxidant effects.Magnolol also demonstrates anti-inflammatory activity by interferring with NF-κB signaling.

Specifications

Synonyms

Specifications & Purity

Moligand™, ≥98%(HPLC)

Biochemical and Physiological Mechanisms

Potent antioxidant. Inhibits iNOS expression (IC 50 = 16.8 μM). Anti-inflammatory, antioxidative, antitumor, antimicrobial and apoptotic agent. Induces apoptosis by upregulating p53 and bax expression. Honokiol ( Asc 647 ) isomer.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%(HPLC)

Names and Identifiers

Pubchem Sid

488184686

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488184686

Canonical Smiles

C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O

IUPAC Name

2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol

InChIKey

VVOAZFWZEDHOOU-UHFFFAOYSA-N

INCHI

1S/C18H18O2/c1-3-5-13-7-9-17(19)15(11-13)16-12-14(6-4-2)8-10-18(16)20/h3-4,7-12,19-20H,1-2,5-6H2

Isomeric SMILES

C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O

WGK Germany

RTECS

DV5105500

UN Number

3077

Molecular Weight

266.33

Beilstein

6(4)6918

Reaxy-Rn

1982224

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1982224&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Biphenyls and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Biphenyls and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Biphenyls and derivatives
Alternative Parents	1-hydroxy-2-unsubstituted benzenoids Organooxygen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Biphenyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
External Descriptors	Neolignans
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

MGAM Tclin Maltase-glucoamylase (654 Activities)

Discover Target: MGAM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH2 Tclin Aldehyde dehydrogenase (509 Activities)

Discover Target: ALDH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)

Discover Target: CNR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

Discover Target: ALOX15B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MTNR1A Tclin Melatonin receptor 1A (2519 Activities)

Discover Target: MTNR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PARP1 Tclin Poly [ADP-ribose] polymerase-1 (6206 Activities)

Discover Target: PARP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AGS (1999 Activities)

Lot Number	Certificate Type	Date	Item
A1608044	Certificate of Analysis	Oct 13, 2026	M111378
B2324757	Certificate of Analysis	Jul 30, 2026	M111378
B2324756	Certificate of Analysis	Jul 30, 2026	M111378
B2324755	Certificate of Analysis	Jul 30, 2026	M111378
B2324754	Certificate of Analysis	Jul 30, 2026	M111378
A2108064	Certificate of Analysis	Apr 15, 2026	M111378
C2627598	Certificate of Analysis	Apr 02, 2026	M111378
C2627600	Certificate of Analysis	Apr 02, 2026	M111378
C2627599	Certificate of Analysis	Apr 02, 2026	M111378
E2413401	Certificate of Analysis	Feb 05, 2026	M111378
I2501473	Certificate of Analysis	Sep 04, 2025	M111378
I2501472	Certificate of Analysis	Sep 04, 2025	M111378
C2512763	Certificate of Analysis	Mar 18, 2025	M111378
C2512769	Certificate of Analysis	Mar 18, 2025	M111378
E2413402	Certificate of Analysis	May 17, 2024	M111378
E2413400	Certificate of Analysis	May 17, 2024	M111378
H2309540	Certificate of Analysis	Aug 15, 2023	M111378
H2309530	Certificate of Analysis	Aug 15, 2023	M111378
H2309543	Certificate of Analysis	Aug 15, 2023	M111378
H2309546	Certificate of Analysis	Aug 15, 2023	M111378
G2128104	Certificate of Analysis	May 09, 2023	M111378
G2128107	Certificate of Analysis	May 09, 2023	M111378
G2128108	Certificate of Analysis	May 09, 2023	M111378
B2324796	Certificate of Analysis	Mar 07, 2023	M111378
D2126284	Certificate of Analysis	Feb 08, 2023	M111378
A2220108	Certificate of Analysis	Jan 27, 2022	M111378
A2220107	Certificate of Analysis	Jan 27, 2022	M111378
A2220451	Certificate of Analysis	Jan 27, 2022	M111378
A2220115	Certificate of Analysis	Jan 25, 2022	M111378
A2220114	Certificate of Analysis	Jan 25, 2022	M111378
A2220121	Certificate of Analysis	Jan 25, 2022	M111378

Sensitivity	Heat Sensitive
Boil Point(°C)	180 °C/1 mmHg
Melt Point(°C)	101 °C
Molecular Weight	266.300 g/mol
XLogP3	5.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	266.131 Da
Monoisotopic Mass	266.131 Da
Topological Polar Surface Area	40.500 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	293.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Magnolol - Moligand™, ≥98%(HPLC) , CAS No.528-43-8

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

Frequently Asked Questions

📚 Citations by Application

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