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· · COA & SDS available for every product · Same-day shipping on in-stock items ML 265 - Moligand™, ≥98% , Activator of pyruvate kinase M1/2, CAS No.1221186-53-3, Activator of pyruvate kinase M1/2
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
AS-16621 | MLS006010294 | A901578 | [6-(3-Aminobenzyl)-4-methyl-5-oxo-5,6-dihydro-4H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-2-yl](methyl)sulfoniumolate | DB01996 | FT-0663861 | 2-METHYLPYRIDINE [HSDB] | 4-methyl morpholine | ML265 | ML-265 | SMR00470136
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
AS-16621 | MLS006010294 | A901578 | [6-(3-Aminobenzyl)-4-methyl-5-oxo-5, 6-dihydro-4H-thieno[2', 3':4, 5]pyrrolo[2, 3-d]pyridazin-2-yl](methyl)sulfoniumolate | DB01996 | FT-0663861 | 2-METHYLPYRIDINE [HSDB] | 4-methyl morpholine | ML265 | ML-265 | SMR00470136
Specifications & Purity
Moligand™, ≥98%
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Activator of pyruvate kinase M1/2
Names and Identifiers Pubchem Sid 488200983 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488200983 Canonical Smiles CN1C2=C(C3=C1C(=O)N(N=C3)CC4=CC(=CC=C4)N)SC(=C2)S(=O)C IUPAC Name 10-[(3-aminophenyl)methyl]-7-methyl-4-methylsulfinyl-3-thia-7,10,11-triazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),4,11-tetraen-9-one InChIKey ZWKJWVSEDISQIS-UHFFFAOYSA-N INCHI 1S/C17H16N4O2S2/c1-20-13-7-14(25(2)23)24-16(13)12-8-19-21(17(22)15(12)20)9-10-4-3-5-11(18)6-10/h3-8H,9,18H2,1-2H3 Isomeric SMILES CN1C2=C(C3=C1C(=O)N(N=C3)CC4=CC(=CC=C4)N)SC(=C2)S(=O)C Molecular Weight 372.5 Reaxy-Rn 20138466 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20138466&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Thienopyrroles Subclass Not available Intermediate Tree Nodes Not available Direct Parent Thienopyrroles Alternative Parents Aniline and substituted anilines 2,3,5-trisubstituted thiophenes Pyridazinones N-methylpyrroles Heteroaromatic compounds Sulfoxides Lactams Sulfinyl compounds Azacyclic compounds Primary amines Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Aniline or substituted anilines - 2,3,5-trisubstituted thiophene - Thienopyrrole - Pyridazinone - Monocyclic benzene moiety - N-methylpyrrole - Pyridazine - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Thiophene - Lactam - Sulfoxide - Azacycle - Sulfinyl compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as thienopyrroles. These are heterocyclic compounds containing a thiophene ring fused to a pyrrole ring. Thiophene is 5-membered ring consisting of four carbon atoms and one sulfur atom. Pyrrole is 5-membered ring consisting of four carbon atoms and one nitrogen atom. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Soluble in DMSO (~10 mg/ml). Refractive Index n20D1.81 (Predicted) Boil Point(°C) ~711.6° C at 760 mmHg (Predicted) Molecular Weight 372.500 g/mol XLogP3 1.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 3 Exact Mass 372.071 Da Monoisotopic Mass 372.071 Da Topological Polar Surface Area 128.000 Ų Heavy Atom Count 25 Formal Charge 0 Complexity 601.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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