MLCK inhibitor peptide 18 TFA, Inhibitor of myosin light chain kinase, CAS No.224579-74-2(free basis), Inhibitor of myosin light chain kinase

CAS: 224579-74-2(free basis) Cat. No.: M287814 Molecular Weight: 1324.64(free basis)

GRADE & PURITY Moligand™, ≥98%

Overview

MLCK inhibitor peptide 18 TFA is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.

Specifications

Product Name

MLCK inhibitor peptide 18 TFA, Inhibitor of myosin light chain kinase, CAS No.224579-74-2(free basis)

Synonyms

Myosin Light Chain Kinase Inhibitor Peptide 18

Grade

Moligand™

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

Selective competitive inhibitor of myosin light chain kinase (IC50= 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.

Sequence

Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2

Action Type

INHIBITOR

Mechanism of action

Inhibitor of myosin light chain kinase

CAS

224579-74-2(free basis)

Molecule Type

Peptide

Storage and Shipping

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Associated Targets(Human)

MYLK Tchem Myosin light chain kinase, smooth muscle (0 Activities)

Discover Target: MYLK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Genetic information

• Alternate Names: Myosin Light Chain Kinase Inhibitor Peptide 18
• Reference:
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