Neuraminidase from Clostridium perfringens, CAS No.9001-67-6

CAS: 9001-67-6 Cat. No.: N128390 EC Number: 232-624-6

GRADE & PURITY EnzymoPure™, ≥0.5 units/mg dry weight

Accession #

P00634

Overview

Neuraminidase (sialidase) removes N-acetyl neuraminic acid (sialic acid) from a variety of glycoproteins. The enzyme has an optimum pH of 5.0-5.1. Little or no activity is observed at pH 4.0 or above pH 8.0.
A hydrolytic enzyme that removes sialic acid from mucoproteins

Specifications

Product Name

Neuraminidase from Clostridium perfringens, CAS No.9001-67-6

Synonyms

Acyl-neuraminyl Hydrolase | Receptor-destroying enzyme | Sialidase | Neuraminidase, Clostridium perfringens

Grade

EnzymoPure™

Specifications & Purity

EnzymoPure™, ≥0.5 units/mg dry weight

Biochemical and Physiological Mechanisms

Hydrolyzes α(2→3), α(2→6), and α(2→8)-glycosidic linkages of terminal sialic residues of various glycomolecules.

Accession #

P00634

CAS

9001-67-6

Enzyme Commission Number

3.2.1.18

Molecule Type

Enzyme

Storage and Shipping

Concentration

≥0.5 units/mg dry weight

Storage

Store at 2-8°C

Shipped In

Wet ice

Unit definition

One Unit releases one micromole of sialic acid per minute at 37°C, pH 5.0, from bovine submaxillary mucin.

References

1. Qian Wang, Zichao Peng, Bin Gui, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Libo He.  (2025)  Sialic acid serves as a functional receptor for grass carp reovirus.  PLoS Pathogens,  21  (9): (e1013481).  [PMID:40911632] [10.1371/journal.ppat.1013481]

2. Yifei Wang, Mengyi Zhang, Yimeng An, Lanshu Li, Hao Wu, Ziqi Cheng, Ling Pan, Chaoying Yang, Weijin Huang, Yansheng Geng, Chenyan Zhao.  (2025)  A Bioluminescent Imaging Mouse Model for Seasonal Influenza Virus Infection Based on a Pseudovirus System.  Viruses-Basel,  17  (5): (686).  [PMID:40431697] [10.3390/v17050686]