Nicotinic acid adenine dinucleotide sodium salt (NAAD Na) - Moligand™, ≥98% , CAS No.104809-30-5

CAS: 104809-30-5 Cat. No.: N356400 Molecular Weight: 686.4 EC Number: 634-641-8 PubChem CID: 91872645

GRADE & PURITY Moligand™, ≥98%

Synonyms

NAAD sodium salt | AKOS040753193 | Deamido Nad sodium salt | NAAD (sodium) | NAAD Na, NaAD | Sodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Nicotinic acid adenine dinucleotide sodium salt is used to study the structure of nicotinate mononucleotide adenylyltransferases. It is used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetases. It can also be used as a cosubstrate to study mechanisms of members of the Sir2 class of NAD(+)-dependent deacetylases.

Specifications

Synonyms

NAAD sodium salt | AKOS040753193 | Deamido Nad sodium salt | NAAD (sodium) | NAAD Na, NaAD | Sodium;[[(2R, 3S, 4R, 5R)-5-(6-aminopurin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R, 3S, 4R, 5R)-5-(3-carboxypyridin-1-ium-1-yl)-3, 4-dihydroxyoxolan-

Specifications & Purity

Moligand™, ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504772685
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504772685
• Canonical Smiles: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)O.[Na+]
• IUPAC Name: sodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• InChIKey: LFHLUTZTSGEADU-RHANTIMGSA-M
• INCHI: 1S/C21H26N6O15P2.Na/c22-17-12-18(24-7-23-17)27(8-25-12)20-16(31)14(29)11(41-20)6-39-44(36,37)42-43(34,35)38-5-10-13(28)15(30)19(40-10)26-3-1-2-9(4-26)21(32)33;/h1-4,7-8,10-11,13-16,19-20,28-31H,5-6H2,(H4-,22,23,24,32,33,34,35,36,37);/q;+1/p-1/t10-,11-,13-,14-,15-,16-,19-,20-;/m1./s1
• Isomeric SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)O.[Na+]
• WGK Germany: 3
• PubChem CID: 91872645
• Molecular Weight: 686.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside monophosphates Nicotinic acid nucleotides Pentose phosphates Glycosylamines 6-aminopurines Monosaccharide phosphates Organic pyrophosphates Pyridinecarboxylic acids Aminopyrimidines and derivatives Alkyl phosphates Pyridinium derivatives Imidolactams N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Amino acids Secondary alcohols Oxacyclic compounds Carboxylic acids Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives Primary amines Organic zwitterions Organic sodium salts Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside diphosphate - Purine ribonucleoside monophosphate - Nicotinic-acid-nucleotide - Pyridine nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Organic pyrophosphate - Imidazopyrimidine - Pyridine carboxylic acid or derivatives - Pyridine carboxylic acid - Purine - Aminopyrimidine - Imidolactam - Alkyl phosphate - Monosaccharide - N-substituted imidazole - Pyrimidine - Pyridinium - Pyridine - Organic phosphoric acid derivative - Phosphoric acid ester - Vinylogous amide - Azole - Imidazole - Oxolane - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Carboxylic acid derivative - Azacycle - Carboxylic acid - Organic alkali metal salt - Organic salt - Alcohol - Organic zwitterion - Organic sodium salt - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Amine - Organonitrogen compound - Organooxygen compound - Organic oxide - Primary amine - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (50 mg/ml).
• Sensitivity: Moisture sensitive