sorbinil - Moligand™,≥98% , Aldose reductase inhibitor, CAS No.68367-52-2, Aldose reductase inhibitor

CAS: 68367-52-2 Cat. No.: S613657 Molecular Weight: 236.20 EC Number: 684-722-7
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
Q1259458 | SORBINIL [WHO-DD] | CCG-221489 | Sorbinilo | Sorbinilo [Spanish] | (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione | HMS3260F11 | NSC 355082 | Sorbinil [USAN:INN:BAN] | Sorbinilum [Latin] | Sorbinil | (S)-6-Fluorospiro(ch
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Size
Status
Price
Qty
1mg
S613657-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$37.90
5mg
S613657-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$119.90
25mg
S613657-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Q1259458 | SORBINIL [WHO-DD] | CCG-221489 | Sorbinilo | Sorbinilo [Spanish] | (4S)-6-fluorospiro[2, 3-dihydrochromene-4, 5'-imidazolidine]-2', 4'-dione | HMS3260F11 | NSC 355082 | Sorbinil [USAN:INN:BAN] | Sorbinilum [Latin] | Sorbinil | (S)-6-Fluorospiro(ch
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Aldose reductase inhibitor
Purity
≥98%
Names and Identifiers
Canonical SmilesC1COC2=C(C13C(=O)NC(=O)N3)C=C(C=C2)F
IUPAC Name(4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione
InChIKeyLXANPKRCLVQAOG-NSHDSACASA-N
INCHI1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1
Isomeric SMILES C1COC2=C([C@]13C(=O)NC(=O)N3)C=C(C=C2)F
WGK Germany 3
Molecular Weight 236.20
Reaxy-Rn 1083383
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1083383&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassAzolidines
SubclassImidazolidines
Intermediate Tree Nodes Imidazolidinones - Imidazolidinediones
Direct ParentHydantoins
Alternative Parents 1-benzopyrans  Alpha amino acids and derivatives  5-monosubstituted hydantoins  Alkyl aryl ethers  N-acyl ureas  Aryl fluorides  Benzenoids  Dicarboximides  Azacyclic compounds  Oxacyclic compounds  Carbonyl compounds  Hydrocarbon derivatives  Organic oxides  Organofluorides  Organonitrogen compounds  Organopnictogen compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Hydantoin - Alpha-amino acid or derivatives - Chromane - 1-benzopyran - Benzopyran - 5-monosubstituted hydantoin - Alkyl aryl ether - N-acyl urea - Ureide - Aryl fluoride - Aryl halide - Benzenoid - Dicarboximide - Carbonic acid derivative - Urea - Carboxylic acid derivative - Oxacycle - Ether - Azacycle - Organic nitrogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Carbonyl group - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as hydantoins. These are heterocyclic compounds containing an imidazolidine substituted by ketone group at positions 2 and 4.
External Descriptors organofluorine compound - imidazolidinone - azaspiro compound - chromanes - oxaspiro compound
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
AKR1B1 Tclin Aldose reductase (18 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1A1 Tchem Aldehyde reductase (91 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SORD Tchem Sorbitol dehydrogenase (133 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSR Tclin Glutathione reductase (335 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B10 Tchem Aldo-keto reductase family 1 member B10 (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NFKB2 Tchem Nuclear factor NF-kappa-B complex (2307 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Akr1c21 Aldo-keto reductase family 1 member C21 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
D2607570Certificate of AnalysisJan 04, 2026 S613657
D2607571Certificate of AnalysisJan 04, 2026 S613657
D2607572Certificate of AnalysisJan 04, 2026 S613657
Chemical and Physical Properties
Molecular Weight236.200 g/mol
XLogP30.700
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass236.06 Da
Monoisotopic Mass236.06 Da
Topological Polar Surface Area67.400 Ų
Heavy Atom Count17
Formal Charge0
Complexity376.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

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