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- Metabolic pathways 2866
- Protein modification; protein ubiquitination. 798
- PI3K-Akt signaling pathway 702
- Endocytosis 618
- Human T-cell leukemia virus 1 infection 600
- MAPK signaling pathway 590
- Kaposi sarcoma-associated herpesvirus infection 504
- Thermogenesis 468
- Phagosome 460
- Ras signaling pathway 460
- Cell adhesion molecules (CAMs) 454
- cAMP signaling pathway 434
- Rap1 signaling pathway 426
- Regulation of actin cytoskeleton 424
- Proteoglycans in cancer 402
- Focal adhesion 396
- Calcium signaling pathway 390
- Natural killer cell mediated cytotoxicity 390
- Huntington disease 388
- Tuberculosis 378
- Chemokine signaling pathway 374
- Axon guidance 360
- NOD-like receptor signaling pathway 348
- Alzheimer disease 342
- Tight junction 338
- Hepatocellular carcinoma 336
- Protein processing in endoplasmic reticulum 330
- JAK-STAT signaling pathway 322
- Cushing syndrome 316
- RNA transport 314
- Oxytocin signaling pathway 310
- Hepatitis C 308
- Hippo signaling pathway 308
- Adrenergic signaling in cardiomyocytes 304
- mTOR signaling pathway 304
- Necroptosis 302
- Non-alcoholic fatty liver disease (NAFLD) 300
- Phospholipase D signaling pathway 298
- Gastric cancer 296
- Protein modification; protein glycosylation. 296
- Retrograde endocannabinoid signaling 296
- Breast cancer 294
- Estrogen signaling pathway 280
- Signaling pathways regulating pluripotency of stem cells 278
- Fluid shear stress and atherosclerosis 276
- Viral myocarditis 276
- Autophagy - animal 274
- Apelin signaling pathway 272
- Ubiquitin mediated proteolysis 272
- Dopaminergic synapse 270
- Vascular smooth muscle contraction 270
- Ribosome 268
- Oxidative phosphorylation 266
- Relaxin signaling pathway 264
- Autoimmune thyroid disease 260
- FoxO signaling pathway 258
- Purine metabolism 254
- Platelet activation 252
- Cell cycle 250
- Oocyte meiosis 250
- Toxoplasmosis 248
- Lysosome 246
- Type I diabetes mellitus 244
- Yersinia infection 242
- AMPK signaling pathway 240
- Graft-versus-host disease 240
- Neurotrophin signaling pathway 238
- Sphingolipid signaling pathway 238
- Th17 cell differentiation 238
- Thyroid hormone signaling pathway 238
- Carbon metabolism 234
- Allograft rejection 232
- Glutamatergic synapse 232
- Serotonergic synapse 230
- TNF signaling pathway 224
- Parathyroid hormone synthesis, secretion and action 220
- Glucagon signaling pathway 218
- HIF-1 signaling pathway 218
- Insulin resistance 216
- Systemic lupus erythematosus 216
- Amoebiasis 208
- C-type lectin receptor signaling pathway 208
- Chagas disease (American trypanosomiasis) 208
- Th1 and Th2 cell differentiation 208
- Pancreatic secretion 206
- Rheumatoid arthritis 206
- Staphylococcus aureus infection 206
- Inflammatory mediator regulation of TRP channels 204
- T cell receptor signaling pathway 204
- Aldosterone synthesis and secretion 202
- AGE-RAGE signaling pathway in diabetic complications 200
- Circadian entrainment 200
- Endocrine resistance 200
- Toll-like receptor signaling pathway 200
- Phosphatidylinositol signaling system 198
- Dilated cardiomyopathy (DCM) 196
- Choline metabolism in cancer 194
- Prostate cancer 194
- Glycerophospholipid metabolism 192
- GnRH signaling pathway 190
- Protein digestion and absorption 190
- TGF-beta signaling pathway 186
- IL-17 signaling pathway 184
- Small cell lung cancer 184
- Fc gamma R-mediated phagocytosis 182
- Gap junction 182
- Hypertrophic cardiomyopathy (HCM) 180
- Salivary secretion 180
- GABAergic synapse 178
- Longevity regulating pathway 178
- ECM-receptor interaction 176
- PD-L1 expression and PD-1 checkpoint pathway in cancer 176
- mRNA surveillance pathway 176
- Leishmaniasis 174
- Cardiac muscle contraction 172
- ErbB signaling pathway 168
- Peroxisome 166
- Salmonella infection 160
- B cell receptor signaling pathway 158
- Complement and coagulation cascades 158
- EGFR tyrosine kinase inhibitor resistance 158
- Gastric acid secretion 156
- RNA degradation 156
- Synaptic vesicle cycle 156
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) 154
- Chronic myeloid leukemia 154
- Drug metabolism - other enzymes 154
- Inflammatory bowel disease (IBD) 154
- Ribosome biogenesis in eukaryotes 154
- PPAR signaling pathway 152
- Bile secretion 150
- Pertussis 150
- Platinum drug resistance 150
- Inositol phosphate metabolism 148
- p53 signaling pathway 148
- Bacterial invasion of epithelial cells 146
- Melanoma 146
- Metabolism of xenobiotics by cytochrome P450 146
- Renin secretion 144
- Adherens junction 142
- Amphetamine addiction 142
- Epithelial cell signaling in Helicobacter pylori infection 140
- Adipocytokine signaling pathway 138
- Central carbon metabolism in cancer 138
- Drug metabolism - cytochrome P450 138
- Chemical carcinogenesis 136
- Cortisol synthesis and secretion 136
- Glycolysis / Gluconeogenesis 136
- Renal cell carcinoma 136
- Long-term potentiation 134
- Non-small cell lung cancer 134
- Shigellosis 134
- Acute myeloid leukemia 132
- Fc epsilon RI signaling pathway 132
- Mitophagy - animal 130
- Retinol metabolism 130
- GnRH secretion 128
- Basal cell carcinoma 126
- Arachidonic acid metabolism 124
- Cytosolic DNA-sensing pathway 124
- Longevity regulating pathway - multiple species 124
- Glycerolipid metabolism 122
- Long-term depression 122
- Lysine degradation 118
- Steroid hormone biosynthesis 118
- Endometrial cancer 116
- Regulation of lipolysis in adipocytes 116
- VEGF signaling pathway 116
- Fatty acid metabolism 114
- Glutathione metabolism 112
- Legionellosis 112
- Pyrimidine metabolism 110
- Pathogenic Escherichia coli infection 108
- Endocrine and other factor-regulated calcium reabsorption 106
- Mineral absorption 106
- Vibrio cholerae infection 106
- Fanconi anemia pathway 104
- Amyotrophic lateral sclerosis (ALS) 102
- Cholesterol metabolism 102
- N-Glycan biosynthesis 100
- Cysteine and methionine metabolism 98
- Arginine and proline metabolism 96
- Malaria 94
- Vasopressin-regulated water reabsorption 94
- Ether lipid metabolism 92
- Nucleotide excision repair 92
- Type II diabetes mellitus 92
- ABC transporters 90
- Aminoacyl-tRNA biosynthesis 88
- Basal transcription factors 88
- Fatty acid degradation 88
- Asthma 84
- Bladder cancer 84
- Carbohydrate digestion and absorption 84
- Homologous recombination 84
- Tryptophan metabolism 84
- Fat digestion and absorption 82
- Ferroptosis 82
- Porphyrin and chlorophyll metabolism 82
- Glycine, serine and threonine metabolism 80
- Nicotine addiction 80
- Pyruvate metabolism 78
- Various types of N-glycan biosynthesis 78
- Aldosterone-regulated sodium reabsorption 74
- Alanine, aspartate and glutamate metabolism 72
- DNA replication 72
- Nicotinate and nicotinamide metabolism 72
- Primary immunodeficiency 72
- Prion diseases 72
- African trypanosomiasis 70
- Propanoate metabolism 68
- SNARE interactions in vesicular transport 68
- Starch and sucrose metabolism 68
- Apoptosis - multiple species 66
- Base excision repair 66
- Fructose and mannose metabolism 66
- beta-Alanine metabolism 66
- Autophagy - other 64
- RNA polymerase 64
- Antifolate resistance 62
- Circadian rhythm 60
- Citrate cycle (TCA cycle) 60
- Mucin type O-glycan biosynthesis 60
- Butanoate metabolism 56
- Hippo signaling pathway - multiple species 56
- Linoleic acid metabolism 56
- Biosynthesis of unsaturated fatty acids 54
- Collecting duct acid secretion 54
- Fatty acid elongation 54
- Folate biosynthesis 54
- Maturity onset diabetes of the young 52
- Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 50
- Vitamin digestion and absorption 48
- alpha-Linolenic acid metabolism 48
- Histidine metabolism 46
- Mannose type O-glycan biosynthesis 46
- Mismatch repair 46
- Protein export 46
- Proximal tubule bicarbonate reclamation 46
- Renin-angiotensin system 46
- Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. 44
- Other types of O-glycan biosynthesis 44
- Terpenoid backbone biosynthesis 42
- One carbon pool by folate 38
- Pantothenate and CoA biosynthesis 38
- Steroid biosynthesis 38
- Fatty acid biosynthesis 36
- Other glycan degradation 36
- 2-Oxocarboxylic acid metabolism 34
- Phenylalanine metabolism 34
- Primary bile acid biosynthesis 34
- Protein modification; protein sumoylation. 34
- Selenocompound metabolism 34
- Glycosphingolipid biosynthesis - ganglio series 30
- Lipid metabolism; fatty acid biosynthesis. 30
- Lipid metabolism; sphingolipid metabolism. 30
- Lipid metabolism; fatty acid beta-oxidation. 26
- Cofactor biosynthesis; ubiquinone biosynthesis. 22
- Glycan metabolism; heparan sulfate biosynthesis. 22
- Taurine and hypotaurine metabolism 22
- Ubiquinone and other terpenoid-quinone biosynthesis 22
- Carbohydrate biosynthesis; gluconeogenesis. 20
- Synthesis and degradation of ketone bodies 20
- Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. 18
- Sulfur relay system 18
- Cofactor metabolism; retinol metabolism. 16
- Riboflavin metabolism 16
- Lipid metabolism; fatty acid metabolism. 14
- Lipid metabolism; phospholipid metabolism. 14
- Lipid metabolism; polyunsaturated fatty acid biosynthesis. 14
- One-carbon metabolism; tetrahydrofolate interconversion. 14
- Protein modification; peptidyl-diphthamide biosynthesis. 14
- Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3. 12
- Phosphonate and phosphinate metabolism 12
- Sulfur metabolism; glutathione metabolism. 12
- Vitamin B6 metabolism 12
- tRNA modification; wybutosine-tRNA(Phe) biosynthesis. 12
- Caffeine metabolism 10
- Carbohydrate metabolism; hexose metabolism. 10
- Cofactor biosynthesis; molybdopterin biosynthesis. 10
- D-Glutamine and D-glutamate metabolism 10
- Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1. 10
- Glycan biosynthesis; glycogen biosynthesis. 10
- Glycan metabolism; heparin biosynthesis. 10
- Glycerolipid metabolism; triacylglycerol biosynthesis. 10
- Lipid metabolism; hydroperoxy eicosatetraenoic acid biosynthesis. 10
- Lipid metabolism; mitochondrial fatty acid beta-oxidation. 10
- Phenylalanine, tyrosine and tryptophan biosynthesis 10
- Steroid biosynthesis; estrogen biosynthesis. 10
- Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2. 8
- Amino-sugar metabolism; N-acetylneuraminate degradation. 8
- Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5. 8
- Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. 8
- Glycan metabolism; chondroitin sulfate biosynthesis. 8
- Lipid metabolism; prostaglandin biosynthesis. 8
- Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. 8
- Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3. 8
- Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. 8
- Protein modification; protein neddylation. 8
- Steroid biosynthesis; cholesterol biosynthesis. 8
- Valine, leucine and isoleucine biosynthesis 8
- tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. 8
- Amine and polyamine biosynthesis; carnitine biosynthesis. 6
- Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. 6
- Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1. 6
- Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2. 6
- Amino-acid degradation; L-valine degradation. 6
- Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. 6
- Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. 6
- Carbohydrate metabolism; galactose metabolism. 6
- Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. 6
- Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1. 6
- Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1. 6
- Genetic information processing; DNA replication. 6
- Glycan biosynthesis; glycogen metabolism. 6
- Glycan biosynthesis; hyaluronan biosynthesis. 6
- Glycerolipid metabolism; triacylglycerol degradation. 6
- Hormone biosynthesis; thyroid hormone biosynthesis. 6
- Lipid metabolism. 6
- Lipid metabolism; bile acid biosynthesis. 6
- Lipid metabolism; steroid biosynthesis. 6
- Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. 6
- Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3. 6
- Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis. 6
- Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2. 6
- Protein modification; carbohydrate sulfation. 6
- Purine metabolism; 3',5'-cyclic GMP degradation; GMP from 3',5'-cyclic GMP: step 1/1. 6
- Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1. 6
- Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. 6
- Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. 6
- Signal transduction; phosphatidylinositol signaling pathway. 6
- Amine and polyamine degradation; putrescine degradation; N-acetylputrescine from putrescine: step 1/1. 4
- Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2. 4
- Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1. 4
- Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (BhmT route): step 1/1. 4
- Amino-acid biosynthesis; beta-alanine biosynthesis. 4
- Amino-acid degradation; L-alanine degradation via transaminase pathway; pyruvate from L-alanine: step 1/1. 4
- Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3. 4
- Amino-sugar metabolism; N-acetylneuraminate biosynthesis. 4
- Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1. 4
- Aromatic compound metabolism; melatonin biosynthesis; melatonin from serotonin: step 1/2. 4
- Aromatic compound metabolism; serotonin biosynthesis; serotonin from L-tryptophan: step 1/2. 4
- Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5. 4
- Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. 4
- Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. 4
- Carbohydrate metabolism; tricarboxylic acid cycle. 4
- Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1. 4
- Cofactor biosynthesis; NAD(+) biosynthesis. 4
- Cofactor biosynthesis; adenosylcobalamin biosynthesis. 4
- Cofactor biosynthesis; iron-sulfur cluster biosynthesis. 4
- Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1. 4
- Cofactor degradation; phylloquinone degradation. 4
- Glycan metabolism; N-glycan degradation. 4
- Glycan metabolism; N-glycan metabolism. 4
- Hormone biosynthesis; cholecalciferol biosynthesis. 4
- Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1. 4
- Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1. 4
- Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1. 4
- Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1. 4
- Lipid metabolism; glycerolipid metabolism. 4
- Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. 4
- Lipid metabolism; peroxisomal fatty acid beta-oxidation. 4
- Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3. 4
- Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1. 4
- Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3. 4
- Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. 4
- Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2. 4
- Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1. 4
- Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2. 4
- Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2. 4
- Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 3/3. 4
- Phospholipid metabolism; phosphatidylserine biosynthesis. 4
- Pigment biosynthesis; melanin biosynthesis. 4
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1. 4
- Protein degradation; proteasomal ubiquitin-dependent pathway. 4
- Protein modification; eIF5A hypusination. 4
- Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2. 4
- Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1. 4
- Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2. 4
- Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1. 4
- Pyrimidine metabolism; dTTP biosynthesis. 4
- Sphingolipid metabolism; galactosylceramide biosynthesis. 4
- Steroid metabolism; cholesterol metabolism. 4
- Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2. 4
- Sulfur metabolism; sulfate assimilation. 4
- tRNA modification; N(7)-methylguanine-tRNA biosynthesis. 4
- Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1. 2
- Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. 2
- Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. 2
- Amine and polyamine biosynthesis; creatine biosynthesis; creatine from L-arginine and glycine: step 1/2. 2
- Amine and polyamine biosynthesis; creatine biosynthesis; creatine from L-arginine and glycine: step 2/2. 2
- Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1. 2
- Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1. 2
- Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1. 2
- Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1. 2
- Amine and polyamine biosynthesis; spermine biosynthesis; spermine from spermidine: step 1/1. 2
- Amine and polyamine degradation; betaine degradation; sarcosine from betaine: step 1/2. 2
- Amine and polyamine degradation; betaine degradation; sarcosine from betaine: step 2/2. 2
- Amine and polyamine degradation; sarcosine degradation; formaldehyde and glycine from sarcosine: step 1/1. 2
- Amine and polyamine degradation; spermine degradation. 2
- Amine and polyamine metabolism; spermine metabolism. 2
- Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. 2
- Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. 2
- Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. 2
- Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1. 2
- Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6. 2
- Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1. 2
- Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. 2
- Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2. 2
- Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1. 2
- Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3. 2
- Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3. 2
- Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3. 2
- Amino-acid degradation; 4-aminobutanoate degradation. 2
- Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (transferase route): step 1/1. 2
- Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3. 2
- Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3. 2
- Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3. 2
- Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. 2
- Amino-acid degradation; L-kynurenine degradation; kynurenate from L-kynurenine: step 1/2. 2
- Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3. 2
- Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 3/3. 2
- Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 1/6. 2
- Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 2/6. 2
- Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 4/6. 2
- Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6. 2
- Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 1/6. 2
- Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 2/6. 2
- Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6. 2
- Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6. 2
- Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 5/6. 2
- Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6. 2
- Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2. 2
- Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2. 2
- Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2. 2
- Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2. 2
- Amino-acid metabolism; lysine degradation. 2
- Amino-acid metabolism; tryptophan metabolism. 2
- Amino-sugar metabolism; N-acetylneuraminate metabolism. 2
- Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 1/2. 2
- Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2. 2
- Carbohydrate acid metabolism; D-gluconate degradation. 2
- Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 1/2. 2
- Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. 2
- Carbohydrate degradation; glycolysis. 2
- Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. 2
- Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. 2
- Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. 2
- Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. 2
- Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3. 2
- Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. 2
- Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3. 2
- Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2. 2
- Carbohydrate metabolism; fructose metabolism. 2
- Carbohydrate metabolism; pyruvate metabolism. 2
- Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1. 2
- Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2. 2
- Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2. 2
- Catecholamine biosynthesis; (R)-adrenaline biosynthesis; (R)-adrenaline from (R)-noradrenaline: step 1/1. 2
- Catecholamine biosynthesis; (R)-noradrenaline biosynthesis; (R)-noradrenaline from dopamine: step 1/1. 2
- Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 1/2. 2
- Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2. 2
- Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. 2
- Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. 2
- Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3. 2
- Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3. 2
- Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7. 2
- Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5. 2
- Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5. 2
- Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. 2
- Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. 2
- Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5. 2
- Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3. 2
- Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis. 2
- Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine: step 1/1. 2
- Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1. 2
- Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1. 2
- D-Arginine and D-ornithine metabolism 2
- Energy metabolism; oxidative phosphorylation. 2
- Energy metabolism; sulfur metabolism. 2
- Flavonoid metabolism; quercetin degradation. 2
- Glycerolipid metabolism. 2
- Glycerolipid metabolism; ether lipid biosynthesis. 2
- Hormone biosynthesis; testosterone biosynthesis. 2
- Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1. 2
- Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3. 2
- Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 2/3. 2
- Lipid metabolism; C21-steroid hormone metabolism. 2
- Lipid metabolism; leukotriene A4 biosynthesis. 2
- Lipid metabolism; leukotriene B4 biosynthesis. 2
- Lipid metabolism; leukotriene B4 degradation. 2
- Lipid metabolism; leukotriene D4 biosynthesis. 2
- Membrane lipid metabolism; glycerophospholipid metabolism. 2
- Membrane lipid metabolism; sphingolipid biosynthesis. 2
- Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3. 2
- Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from malonyl-CoA: step 1/1. 2
- Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1. 2
- Nitrogen metabolism; urea cycle; L-arginine and fumarate from (N(omega)-L-arginino)succinate: step 1/1. 2
- Nitrogen metabolism; urea cycle; L-citrulline from L-ornithine and carbamoyl phosphate: step 1/1. 2
- Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 1/2. 2
- Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2. 2
- Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1. 2
- Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2. 2
- Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2. 2
- Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2. 2
- Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1. 2
- Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1. 2
- Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1. 2
- Organic acid metabolism; glycolate degradation; 3-phospho-D-glycerate from glycolate: step 1/4. 2
- Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2. 2
- Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 2/2. 2
- Organosulfur degradation. 2
- Phospholipid metabolism. 2
- Phospholipid metabolism; phosphatidylcholine biosynthesis. 2
- Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphocholine from choline: step 1/1. 2
- Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3. 2
- Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2. 2
- Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 2/2. 2
- Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. 2
- Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2. 2
- Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1. 2
- Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1. 2
- Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. 2
- Porphyrin-containing compound metabolism; protoheme degradation. 2
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4. 2
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4. 2
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4. 2
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4. 2
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1. 2
- Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. 2
- Protein biosynthesis; polypeptide chain elongation. 2
- Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2. 2
- Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2. 2
- Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2. 2
- Protein modification; sulfatase oxidation. 2
- Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2. 2
- Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. 2
- Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1. 2
- Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. 2
- Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1. 2
- Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1. 2
- Purine metabolism; guanine degradation; xanthine from guanine: step 1/1. 2
- Purine metabolism; purine nucleoside salvage. 2
- Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3. 2
- Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3. 2
- Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. 2
- Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. 2
- Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2. 2
- Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2. 2
- Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1. 2
- Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2. 2
- Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2. 2
- Quinol/quinone metabolism; menaquinone biosynthesis. 2
- Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2. 2
- Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2. 2
- Secondary metabolite metabolism; quinolate metabolism. 2
- Siderophore biosynthesis. 2
- Sphingolipid metabolism. 2
- Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 1/6. 2
- Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 3/6. 2
- Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6. 2
- Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 5/6. 2
- Steroid hormone biosynthesis. 2
- Steroid metabolism. 2
- Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. 2
- Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3. 2
- Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3. 2
- Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 3/3. 2
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Dto Class
- protein 18460
- Enzyme 4852
- Transporter 1778
- G-protein coupled receptor 1658
- Nucleic acid binding 1578
- Transcription factor 1520
- Class A rhodopsin like 1482
- Enzyme modulator 1410
- Kinase 1272
- Protease 1236
- Protein kinase 1032
- Transferase 946
- Hydrolase 926
- Cellular structure 874
- RNA binding protein 874
- Signaling 854
- Olfactory receptor 842
- SLC superfamily of solute carriers 840
- Oxidoreductase 738
- Ion channel 708
- Receptor 652
- Zinc finger transcription factor 488
- DNA binding protein 460
- C2H2 zinc finger transcription factor 422
- Cysteine protease 416
- Serine protease 400
- Ligase 392
- Actin family cytoskeletal protein 380
- KRAB box transcription factor 372
- G-protein modulator 366
- Protease inhibitor 354
- Metalloprotease 352
- Helix-turn-helix transcription factor 346
- Phosphatase 318
- Microtubule family cytoskeletal protein 314
- Ribosomal protein 302
- Dehydrogenase 284
- G-protein 252
- Immune response 246
- mRNA processing factor 236
- Calcium-binding protein 234
- Glycosyltransferase 230
- Growth factor 230
- Cytokine receptor 218
- Nuclease 214
- Kinase modulator 208
- Homeodomain transcription factor 190
- TK group 186
- Ubiquitin-protein ligase 186
- Nucleotidyltransferase 182
- mRNA splicing factor 182
- Calmodulin 178
- Epigenetic regulator 178
- Intracellular calcium-sensing protein 178
- Other group 164
- Small GTPase 160
- Isomerase 158
- Non-motor actin binding protein 154
- CAMK group 152
- Immunoglobulin 152
- Winged helix/forkhead transcription factor 152
- Transcription cofactor 150
- Chromatin/chromatin-binding protein 146
- Immunoglobulin receptor superfamily 146
- Lipase 146
- Helicase 144
- Cell adhesion 136
- Chaperone 136
- Oxygenase 136
- Membrane trafficking regulatory protein 134
- Polymerase 134
- Serine protease inhibitor 134
- CMGC group 132
- Extracellular structure 130
- Oxidase 130
- AGC group 126
- Non-protein kinase 124
- Cell-cell junction 122
- Basic helix-loop-helix transcription factor 118
- Protein phosphatase 118
- Guanyl-nucleotide exchange factor 116
- Unclassified protein 116
- Non-motor microtubule binding protein 114
- Histone 112
- Acyltransferase 110
- Acetyltransferase 106
- SLC25 family of mitochondrial transporters 106
- Potassium channel family 104
- Cytokine 98
- Lyase 98
- Phosphatase modulator 98
- Translation factor 98
- Chemokine 96
- Nuclear receptor 96
- Hormone 94
- Microtubule binding motor protein 94
- STE group 94
- Kinase activator 92
- Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family 92
- Methyltransferase 90
- Phospholipase 88
- RNA helicase 88
- DNA-directed RNA polymerase 86
- TKL group 86
- ATP-binding cassette transporter family 84
- Extracellular matrix glycoprotein 82
- Reductase 80
- Vesicle coat protein 80
- Heterotrimeric G-protein 78
- F-type and V-type ATPases 72
- P-type ATPases 72
- Tight junction 72
- Membrane-bound signaling molecule 68
- Reader 68
- Adhesion class 66
- Immunoglobulin fold transcription factor 66
- Translation initiation factor 66
- Phosphatase inhibitor 64
- Actin and actin related protein 62
- SLC35 family of nucleotide sugar transporters 62
- Basic leucine zipper transcription factor 60
- Epimerase/racemase 60
- SNARE protein 60
- STE20 family 60
- Eraser 58
- Lipid kinase 58
- Deaminase 56
- Actin binding motor protein 54
- Rel homology transcription factor 54
- DNA helicase 52
- Ribonucleoprotein 52
- Writer 52
- Atypical group 50
- Nucleotide phosphatase 50
- Protein methyltransferase 50
- Aminoacyl-tRNA synthetase 48
- Esterase 48
- Peroxidase 48
- SLC22 family of organic cation and anion transporters 48
- Taste 2 receptor 48
- Aspartic protease 46
- Chemokine receptor 46
- Transient receptor potential calcium channel (TRP-CC) family 46
- V-type ATPase 46
- CAMKL family 44
- Class C metabotropic glutamate/pheromone 44
- DNA-directed DNA polymerase 44
- Tubulin 44
- CDK family 42
- Gap junction 42
- Major histocompatibility complex antigen 42
- Exoribonuclease 40
- Type I cytokine receptor 40
- Gamma-aminobutyric acid receptor subfamily 38
- SLC6 neurotransmitter transporter family 38
- Histone deacetylase 36
- Purinoceptor 36
- Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors 35
- Mitochondrial nucleotide transporter subfamily 34
- Acetylcholine receptor subfamily 32
- Class B secretin like 32
- Glycosidase 32
- Inward rectifier-type potassium channel family 32
- Kinase inhibitor 32
- Transaminase 32
- Intermediate filament 30
- Intermediate filament binding protein 30
- Mitochondrial amino acid transporter subfamily 30
- Neuropeptide 30
- SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 30
- Two pore domain potassium channel family 30
- Bromodomain 28
- Eph family 28
- HMG box transcription factor 28
- MAPK family 28
- Methyl-lysine/arginine binding protein 28
- Other small molecule kinase 28
- Phospholipid-transporting ATPases 28
- SLC16 family of monocarboxylate transporters 28
- SLC39 family of metal ion transporters 28
- mRNA polyadenylation factor 28
- SLC2 family of hexose and sugar alcohol transporters 27
- Apolipoprotein 26
- Chaperonin 26
- Decarboxylase 26
- SLC7 family 26
- SLC9 family of sodium/hydrogen exchangers 26
- F-type ATPase 25
- SRC family 25
- 5-hydroxytryptamine receptor 24
- ABCA subfamily 24
- Aquaporin 24
- C-C chemokine receptor 24
- CK1 group 24
- Calcium channel alpha-1 subunit family 24
- Extracellular matrix structural protein 24
- Other ion channel 24
- SLC5 family of sodium-dependent glucose transporters 24
- STKR family 24
- Type II cytokine receptor 24
- ABCB subfamily 22
- ABCC subfamily 22
- Class F frizzled-type 22
- Damaged DNA-binding protein 22
- Endoribonuclease 22
- Lysine demethylase 22
- NEK family 22
- SLCO family of organic anion transporting polypeptides 22
- Tumor necrosis factor family member 22
- SLC38 family of sodium-dependent neutral amino acid transporters 21
- Cyclic nucleotide-gated cation channel family 20
- DYRK family 20
- SLC30 zinc transporter family 20
- Sodium channel family 20
- Hsp90 family chaperone 19
- MLK family 19
- Orphan or poorly characterized SLC22 family members 19
- PI3/PI4 kinase family 19
- Phosphorylase 19
- SLC4 family of bicarbonate transporters 19
- Adrenoceptor 18
- Amiloride-sensitive sodium channel family 18
- Ca2+-ATPases 18
- Chloride channel family 18
- Frizzled receptor 18
- Mas proto-oncogene and Mas-related (MRGs) receptor 18
- PKC family 18
- SLC12 family of cation-coupled chloride transporters 18
- SLC26 family of anion exchangers 18
- P2Y receptor 17
- SET domain 17
- A (Shaker) subfamily 16
- Antibacterial response protein 16
- Calcium channel auxiliary subunit 1-8 (cca) family 16
- Calcium-activated subfamily 16
- Class II transporters 16
- Endodeoxyribonuclease 16
- Miscellaneous SLC25 mitochondrial transporters 16
- Na+/K+-ATPases 16
- STE11 family 16
- Storage 16
- H (Eag) subfamily 15
- Replication origin binding protein 15
- SLC17 phosphate and organic anion transporter family 15
- ATP-gated p2x receptor cation channel (p2x receptor) family 14
- CK1 family 14
- Cadherin 14
- Carbohydrate kinase 14
- Chromodomain 14
- DMPK family 14
- Jumonji domain-containing 14
- Nucleoside kinase 14
- Phosphodiesterase 14
- HDAC class III 13
- LTrpC subfamily 13
- Metabotropic glutamate receptor 13
- Neurotrophic factor 13
- Protein arginine methyltransferase 13
- RSK family 13
- SLC10 family of sodium-bile acid co-transporters 13
- SLC28 and SLC29 families of nucleoside transporters 13
- STE7 family 13
- Alpha adrenoceptor 12
- Dopamine receptor 12
- GABA transporter subfamily 12
- Glucosidase 12
- Lysophospholipid (LPA) receptor 12
- Mitochondrial di- and tri-carboxylic acid transporter subfamily 12
- Organic anion transporters (OATs) 12
- SLC1 family of amino acid transporters 12
- STKR Type 1 subfamily 12
- STrpC subfamily 12
- Melanin-concentrating hormone receptor 11
- Orphan SLC38 transporters 11
- Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family 11
- SLC24 family of sodium/potassium/calcium exchangers 11
- Sodium-dependent HCO3- transporters 11
- Translation elongation factor 11
- TrpV subfamily 11
- 5-HT1 receptor 10
- 5-HT3 receptor sub-subfamily 10
- 5-hydroxytryptamine receptor subfamily 10
- ABC1 family 10
- ABCG subfamily 10
- Acetylcholine receptor (muscarinic) 10
- Alpha family 10
- CAMK1 family 10
- CDKL family 10
- Calcium-dependent chloride channel (ca-clc) family 10
- Class I transporters 10
- DAPK family 10
- DNA glycosylase 10
- Dehydratase 10
- ERK subfamily 10
- Hexose transporter family 10
- Intracellular chloride channel (clic) family 10
- Mitochondrial uncoupling proteins 10
- Mutase 10
- Neutral amino acid transporter subfamily 10
- Other 7TM proteins 10
- PKA family 10
- PLK family 10
- Polycystin cation channel (pcc) family 10
- SLC13 family of sodium-dependent sulphate/carboxylate transporters 10
- SLC27 family of fatty acid transporters 10
- SLC57 NiPA-like magnesium transporter family 10
- TEC family 10
- Transmembrane channel (TMC) family 10
- Vomeronasal receptor 10
- Leukotriene receptor 9
- MADS box transcription factor 9
- MAPKAPK family 9
- MAST family 9
- MBT domain 9
- Melanocortin receptor 9
- RAF family 9
- SLC44 choline transporter-like family 9
- TAIRE subfamily 9
- 3-Ketosteroid receptors 8
- Adenosine receptor 8
- Angiotensin receptor 8
- Anion channel-forming bestrophin (bestrophin) family 8
- Anion exchangers 8
- C (Shaw) subfamily 8
- C-X-C chemokine receptor 8
- CAMK2 family 8
- CK2 family 8
- CLK family 8
- Calcium channel auxiliary subunit 2 types 1-4 (cca-2) family 8
- Calcium channel auxiliary subunit types 1-4 (cca-) family 8
- Calcium homeostasis modulator calcium channel (calhm-c) family 8
- Calcium-activated potassium channel auxiliary subunit slowpoke- (slo) family 8
- Cation channel sperm-associated family 8
- Cyclase 8
- DNA topoisomerase 8
- EGFR family 8
- Fxyd family 8
- GRK family 8
- Galactosidase 8
- KQT subfamily 8
- Nucleotide kinase 8
- PDHK family 8
- PIKK family 8
- STKR Type 2 subfamily 8
- Surfactant 8
- TSSK family 8
- ULK family 8
- Epithelial chloride channel (e-clc) family 7
- Exodeoxyribonuclease 7
- Glutamate transporter subfamily 7
- Glycine receptor subfamily 7
- Glycosylase 7
- IKK family 7
- IRAK family 7
- LISK family 7
- MARK subfamily 7
- NDR family 7
- Other SLC26 anion exchangers 7
- P38 subfamily 7
- PDGFR family 7
- PEK family 7
- Plant homeodomain 7
- RGC family 7
- RGC group 7
- RIPK family 7
- SLC18 family of vesicular amine transporters 7
- SLC36 family of proton-coupled amino acid transporters 7
- SLC49 family of FLVCR-related heme transporters 7
- 5-HT2 receptor 6
- ABCD subfamily of peroxisomal ABC transporters 6
- AKT family 6
- AUR family 6
- AXL family 6
- Adenylate kinase family 6
- Anaphylatoxin receptor 6
- Anion channel tweety (tweety) family 6
- Beta adrenoceptor 6
- Bombesin receptor 6
- CDK1 subfamily 6
- COUP-TF-like receptors 6
- Cadherin EGF LAG (CELSR) receptor 6
- Carbohydrate phosphatase 6
- D (Shal) subfamily 6
- DCAMKL family 6
- DCK/DGK family 6
- Deacetylase 6
- Diacylglycerol kinase family 6
- Dyrk2 subfamily 6
- FGFR family 6
- Free fatty acid receptor 6
- G subfamily 6
- GEK subfamily 6
- Glucagon receptor 6
- Glycine transporter subfamily 6
- HDAC class IIa 6
- Latrophilin receptor 6
- Neuropeptide Y receptor 6
- Proteinase-activated receptor 6
- SLC15 family of peptide transporters 6
- SLC29 family 6
- SLC45 family of putative sugar transporters 6
- SLC56 Sideroflexins 6
- Translation release factor 6
- Endothelin receptor 5
- Glycoprotein hormone receptor 5
- HIPK subfamily 5
- Hydroxycarboxylic acid receptor 5
- INSR family 5
- Interleukin superfamily 5
- JAKA family 5
- KHS subfamily 5
- Liver X receptor-like receptors 5
- MLK subfamily 5
- NAK family 5
- Nerve growth factor IB-like receptors 5
- Organic cation transporters (OCT) 5
- PAKB subfamily 5
- PKN family 5
- Peroxisome proliferator-activated receptors 5
- QIK subfamily 5
- RCK family 5
- SCY1 family 5
- SLC63 Sphingosine-phosphate transporters 5
- Sodium channel auxiliary subunit 1-4 (sca-) family 5
- Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters 5
- TATA-binding transcription factor 5
- VRK family 5
- ABC1-A subfamily 4
- ABC1-B subfamily 4
- ABL family 4
- ACK family 4
- ALK family 4
- AMPK subfamily 4
- Alanine/serine/cysteine transporter subfamily 4
- Anion channels 4
- Annexin 4
- B (Shab) subfamily 4
- BARK subfamily 4
- BRSK subfamily 4
- BUB family 4
- Bile acid receptor 4
- Bradykinin receptor 4
- CAMK-UNIQUE family 4
- CAMKK family 4
- CDK4 subfamily 4
- CDK8 subfamily 4
- CSK family 4
- Calcitonin receptor 4
- Calcium-sensing receptor 4
- Cannabinoid receptor 4
- Chloride/bicarbonate exchangers 4
- Cholecystokinin receptor 4
- Choline/ethanolamine kinase family 4
- Corticotropin-releasing factor receptor 4
- Cu+-ATPases 4
- Cysteine protease inhibitor 4
- DAX-like receptors 4
- DDR family 4
- DNA ligase 4
- DNA photolyase 4
- Dyrk1 subfamily 4
- Estrogen receptors 4
- Estrogen-related receptors 4
- FER family 4
- Formyl peptide receptor 4
- GABA-B receptor 4
- GRK subfamily 4
- HDAC class I 4
- Hepatocyte nuclear factor-4 receptors 4
- Histamine receptor 4
- Inositol phosphokinase (IPK) family 4
- LIMK subfamily 4
- LMR family 4
- MAPKAPK subfamily 4
- MLCK family 4
- MNK subfamily 4
- MSN subfamily 4
- Monoamine transporter subfamily 4
- NKF4 family 4
- Organic zwitterions/cation transporters (OCTN) 4
- Other-UNIQUE family 4
- PIM family 4
- RIO family 4
- ROR family 4
- RSK subfamily 4
- Retinoic acid receptors 4
- Retinoid X receptors 4
- Runt transcription factor 4
- SLC19 family of vitamin transporters 4
- SLC23 family of ascorbic acid transporters 4
- SLC28 family 4
- SLC37 family of phosphosugar/phosphate exchangers 4
- SLC41 family of divalent cation transporters 4
- SLC42 family of Rhesus glycoprotein ammonium transporters 4
- SLC46 family of folate transporters 4
- SLC52 family of riboflavin transporters 4
- SLC55 Mitochondrial cation/proton exchangers 4
- SRPK family 4
- TAO subfamily 4
- TRIO family 4
- TRK family 4
- Type II pantothenate kinase family 4
- VEGFR family 4
- Voltage-gated potassium channel -subunit (kv) family 4
- WNK family 4
- YANK family 4
- GSK family 3
- GSK subfamily 3
- Galanin receptor 3
- Golgi pH regulator family 3
- IRE family 3
- Immunoglobulin superfamily cell adhesion molecule 3
- JNK subfamily 3
- KCNE subfamily 3
- KCNJ12 subfamily 3
- LRRK family 3
- MET family 3
- Myelin protein 3
- P70 subfamily 3
- Parathyroid hormone receptor 3
- Protein kinase receptor 3
- Retinoic acid-related orphans 3
- SGK family 3
- SLC31 family of copper transporters 3
- SLC34 family of sodium phosphate co-transporters 3
- SLC43 family of large neutral amino acid transporters 3
- TRBL family 3
- Thyroid Hormone Receptors 3
- Tmem38 family 3
- Tumor necrosis factor receptor 3
- Type I sodium-phosphate co-transporters 3
- Vesicular glutamate transporters (VGLUTs) 3
- WEE family 3
- YSK subfamily 3
- 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2
- 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 2
- 1,4-alpha-glucan-branching enzyme 2
- 1,5-anhydro-D-fructose reductase 2
- 1-aminocyclopropane-1-carboxylate synthase-like protein 1 2
- 1-phosphatidylinositol 3-phosphate 5-kinase 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 2
- 10 kDa heat shock protein, mitochondrial 2
- 11-cis retinol dehydrogenase 2
- 116 kDa U5 small nuclear ribonucleoprotein component 2
- 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor 2
- 14-3-3 protein beta/alpha 2
- 14-3-3 protein epsilon 2
- 14-3-3 protein eta 2
- 14-3-3 protein gamma 2
- 14-3-3 protein sigma 2
- 14-3-3 protein theta 2
- 14-3-3 protein zeta/delta 2
- 17-beta-hydroxysteroid dehydrogenase 14 2
- 17-beta-hydroxysteroid dehydrogenase type 6 2
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase 2
- 2',5'-phosphodiesterase 12 2
- 2'-5'-oligoadenylate synthase 1 2
- 2'-5'-oligoadenylate synthase 2 2
- 2'-5'-oligoadenylate synthase 3 2
- 2'-5'-oligoadenylate synthase-like protein 2
- 2,4-dienoyl-CoA reductase, mitochondrial 2
- 2-5a-dependent ribonuclease 2
- 2-acylglycerol O-acyltransferase 1 2
- 2-acylglycerol O-acyltransferase 2 2
- 2-acylglycerol O-acyltransferase 3 2
- 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial 2
- 2-hydroxyacyl-CoA lyase 1 2
- 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 2
- 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 2
- 2-oxoglutarate receptor 1 2
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 2
- 2-phosphoxylose phosphatase 1 2
- 25-hydroxycholesterol 7-alpha-hydroxylase 2
- 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2
- 26S proteasome non-ATPase regulatory subunit 1 2
- 26S proteasome non-ATPase regulatory subunit 12 2
- 26S proteasome non-ATPase regulatory subunit 13 2
- 26S proteasome non-ATPase regulatory subunit 14 2
- 26S proteasome non-ATPase regulatory subunit 2 2
- 26S proteasome non-ATPase regulatory subunit 3 2
- 26S proteasome non-ATPase regulatory subunit 4 2
- 26S proteasome non-ATPase regulatory subunit 7 2
- 26S proteasome non-ATPase regulatory subunit 8 2
- 26S proteasome non-ATPase regulatory subunit 9 2
- 26S proteasome regulatory subunit 10B 2
- 26S proteasome regulatory subunit 4 2
- 26S proteasome regulatory subunit 6A 2
- 26S proteasome regulatory subunit 6B 2
- 26S proteasome regulatory subunit 7 2
- 26S proteasome regulatory subunit 8 2
- 28S ribosomal protein S11, mitochondrial 2
- 28S ribosomal protein S12, mitochondrial 2
- 28S ribosomal protein S14, mitochondrial 2
- 28S ribosomal protein S16, mitochondrial 2
- 28S ribosomal protein S18c, mitochondrial 2
- 28S ribosomal protein S2, mitochondrial 2
- 28S ribosomal protein S21, mitochondrial 2
- 28S ribosomal protein S24, mitochondrial 2
- 28S ribosomal protein S27, mitochondrial 2
- 28S ribosomal protein S29, mitochondrial 2
- 28S ribosomal protein S35, mitochondrial 2
- 28S ribosomal protein S5, mitochondrial 2
- 28S ribosomal protein S7, mitochondrial 2
- 3 beta-hydroxysteroid dehydrogenase type 7 2
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 2
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 2
- 3'(2'),5'-bisphosphate nucleotidase 1 2
- 3'-5' exoribonuclease 1 2
- 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2
- 3-hydroxyacyl-CoA dehydrogenase type-2 2
- 3-hydroxyisobutyrate dehydrogenase, mitochondrial 2
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 2
- 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic 2
- 3-ketoacyl-CoA thiolase, mitochondrial 2
- 3-ketoacyl-CoA thiolase, peroxisomal 2
- 3-mercaptopyruvate sulfurtransferase 2
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1 2
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2
- 3-oxo-5-beta-steroid 4-dehydrogenase 2
- 3-phosphoinositide-dependent protein kinase 1 2
- 39S ribosomal protein L1, mitochondrial 2
- 39S ribosomal protein L11, mitochondrial 2
- 39S ribosomal protein L12, mitochondrial 2
- 39S ribosomal protein L13, mitochondrial 2
- 39S ribosomal protein L14, mitochondrial 2
- 39S ribosomal protein L16, mitochondrial 2
- 39S ribosomal protein L17, mitochondrial 2
- 39S ribosomal protein L18, mitochondrial 2
- 39S ribosomal protein L19, mitochondrial 2
- 39S ribosomal protein L2, mitochondrial 2
- 39S ribosomal protein L20, mitochondrial 2
- 39S ribosomal protein L21, mitochondrial 2
- 39S ribosomal protein L22, mitochondrial 2
- 39S ribosomal protein L23, mitochondrial 2
- 39S ribosomal protein L24, mitochondrial 2
- 39S ribosomal protein L27, mitochondrial 2
- 39S ribosomal protein L35, mitochondrial 2
- 39S ribosomal protein L38, mitochondrial 2
- 39S ribosomal protein L39, mitochondrial 2
- 39S ribosomal protein L41, mitochondrial 2
- 39S ribosomal protein L43, mitochondrial 2
- 39S ribosomal protein L44, mitochondrial 2
- 39S ribosomal protein L47, mitochondrial 2
- 39S ribosomal protein L48, mitochondrial 2
- 39S ribosomal protein L49, mitochondrial 2
- 39S ribosomal protein L51, mitochondrial 2
- 39S ribosomal protein L9, mitochondrial 2
- 39S ribosomal protein S18a, mitochondrial 2
- 4-aminobutyrate aminotransferase, mitochondrial 2
- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial 2
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial 2
- 4-hydroxyphenylpyruvate dioxygenase 2
- 4-hydroxyphenylpyruvate dioxygenase-like protein 2
- 4-trimethylaminobutyraldehyde dehydrogenase 2
- 40S ribosomal protein S10 2
- 40S ribosomal protein S11 2
- 40S ribosomal protein S12 2
- 40S ribosomal protein S13 2
- 40S ribosomal protein S14 2
- 40S ribosomal protein S15 2
- 40S ribosomal protein S15a 2
- 40S ribosomal protein S17 2
- 40S ribosomal protein S18 2
- 40S ribosomal protein S19 2
- 40S ribosomal protein S2 2
- 40S ribosomal protein S20 2
- 40S ribosomal protein S21 2
- 40S ribosomal protein S23 2
- 40S ribosomal protein S24 2
- 40S ribosomal protein S26 2
- 40S ribosomal protein S27 2
- 40S ribosomal protein S27-like 2
- 40S ribosomal protein S28 2
- 40S ribosomal protein S3 2
- 40S ribosomal protein S3a 2
- 40S ribosomal protein S4, X isoform 2
- 40S ribosomal protein S4, Y isoform 1 2
- 40S ribosomal protein S4, Y isoform 2 2
- 40S ribosomal protein S5 2
- 40S ribosomal protein S6 2
- 40S ribosomal protein S7 2
- 40S ribosomal protein S8 2
- 40S ribosomal protein S9 2
- 40S ribosomal protein SA 2
- 45 kDa calcium-binding protein 2
- 4F2 cell-surface antigen heavy chain 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 2
- 5'-AMP-activated protein kinase subunit beta-1 2
- 5'-AMP-activated protein kinase subunit beta-2 2
- 5'-AMP-activated protein kinase subunit gamma-1 2
- 5'-AMP-activated protein kinase subunit gamma-2 2
- 5'-AMP-activated protein kinase subunit gamma-3 2
- 5'-nucleotidase 2
- 5'-nucleotidase domain-containing protein 1 2
- 5'-nucleotidase domain-containing protein 2 2
- 5'-nucleotidase domain-containing protein 3 2
- 5'-nucleotidase domain-containing protein 4 2
- 5,6-dihydroxyindole-2-carboxylic acid oxidase 2
- 5-HT4 receptor 2
- 5-HT5 receptor 2
- 5-HT6 receptor 2
- 5-HT7 receptor 2
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial 2
- 5-aminolevulinate synthase, nonspecific, mitochondrial 2
- 5-formyltetrahydrofolate cyclo-ligase 2
- 5-hydroxytryptamine receptor 1D 2
- 5-hydroxytryptamine receptor 1E 2
- 5-hydroxytryptamine receptor 1a 2
- 5-hydroxytryptamine receptor 1b 2
- 5-hydroxytryptamine receptor 1f 2
- 5-hydroxytryptamine receptor 2A 2
- 5-hydroxytryptamine receptor 2B 2
- 5-hydroxytryptamine receptor 2c 2
- 5-hydroxytryptamine receptor 3A 2
- 5-hydroxytryptamine receptor 3B 2
- 5-hydroxytryptamine receptor 3C 2
- 5-hydroxytryptamine receptor 3d 2
- 5-hydroxytryptamine receptor 3e 2
- 5-hydroxytryptamine receptor 4 2
- 5-hydroxytryptamine receptor 5a 2
- 5-hydroxytryptamine receptor 6 2
- 5-hydroxytryptamine receptor 7 2
- 5-methylcytosine rRNA methyltransferase NSUN4 2
- 5-oxoprolinase 2
- 55 kDa erythrocyte membrane protein 2
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 2
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 2
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2
- 6-phosphogluconate dehydrogenase, decarboxylating 2
- 6-phosphogluconolactonase 2
- 60 kDa SS-A/Ro ribonucleoprotein 2
- 60S ribosomal protein L10 2
- 60S ribosomal protein L10-like 2
- 60S ribosomal protein L10a 2
- 60S ribosomal protein L11 2
- 60S ribosomal protein L12 2
- 60S ribosomal protein L13 2
- 60S ribosomal protein L13a 2
- 60S ribosomal protein L14 2
- 60S ribosomal protein L15 2
- 60S ribosomal protein L18 2
- 60S ribosomal protein L19 2
- 60S ribosomal protein L21 2
- 60S ribosomal protein L22 2
- 60S ribosomal protein L22-like 1 2
- 60S ribosomal protein L23 2
- 60S ribosomal protein L23a 2
- 60S ribosomal protein L24 2
- 60S ribosomal protein L26 2
- 60S ribosomal protein L26-like 1 2
- 60S ribosomal protein L27 2
- 60S ribosomal protein L27a 2
- 60S ribosomal protein L28 2
- 60S ribosomal protein L29 2
- 60S ribosomal protein L3 2
- 60S ribosomal protein L3-like 2
- 60S ribosomal protein L30 2
- 60S ribosomal protein L31 2
- 60S ribosomal protein L32 2
- 60S ribosomal protein L35 2
- 60S ribosomal protein L35a 2
- 60S ribosomal protein L36 2
- 60S ribosomal protein L36a 2
- 60S ribosomal protein L36a-like 2
- 60S ribosomal protein L37 2
- 60S ribosomal protein L38 2
- 60S ribosomal protein L39 2
- 60S ribosomal protein L39-like 2
- 60S ribosomal protein L5 2
- 60S ribosomal protein L6 2
- 60S ribosomal protein L7 2
- 60S ribosomal protein L7-like 1 2
- 60S ribosomal protein L7a 2
- 60S ribosomal protein L8 2
- 60S ribosomal protein L9 2
- 7,8-dihydro-8-oxoguanine triphosphatase 2
- 7-dehydrocholesterol reductase 2
- 7-methylguanosine phosphate-specific 5'-nucleotidase 2
- 72 kDa type IV collagenase 2
- 85/88 kDa calcium-independent phospholipase A2 2
- A disintegrin and metalloproteinase with thrombospondin motifs 1 2
- A disintegrin and metalloproteinase with thrombospondin motifs 10 2
- A disintegrin and metalloproteinase with thrombospondin motifs 12 2
- A disintegrin and metalloproteinase with thrombospondin motifs 13 2
- A disintegrin and metalloproteinase with thrombospondin motifs 14 2
- A disintegrin and metalloproteinase with thrombospondin motifs 15 2
- A disintegrin and metalloproteinase with thrombospondin motifs 16 2
- A disintegrin and metalloproteinase with thrombospondin motifs 17 2
- A disintegrin and metalloproteinase with thrombospondin motifs 18 2
- A disintegrin and metalloproteinase with thrombospondin motifs 19 2
- A disintegrin and metalloproteinase with thrombospondin motifs 2 2
- A disintegrin and metalloproteinase with thrombospondin motifs 20 2
- A disintegrin and metalloproteinase with thrombospondin motifs 3 2
- A disintegrin and metalloproteinase with thrombospondin motifs 4 2
- A disintegrin and metalloproteinase with thrombospondin motifs 5 2
- A disintegrin and metalloproteinase with thrombospondin motifs 6 2
- A disintegrin and metalloproteinase with thrombospondin motifs 7 2
- A disintegrin and metalloproteinase with thrombospondin motifs 8 2
- A disintegrin and metalloproteinase with thrombospondin motifs 9 2
- A-kinase anchor protein 1, mitochondrial 2
- ABC1-C subfamily 2
- ABCC family 2
- ABI gene family member 3 2
- ADAM DEC1 2
- ADAMTS-like protein 1 2
- ADAMTS-like protein 2 2
- ADAMTS-like protein 3 2
- ADAMTS-like protein 4 2
- ADAMTS-like protein 5 2
- ADM 2
- ADM2 2
- ADP-dependent glucokinase 2
- ADP-ribose pyrophosphatase, mitochondrial 2
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 2
- ADP-sugar pyrophosphatase 2
- ADP/ATP translocase 1 2
- ADP/ATP translocase 2 2
- ADP/ATP translocase 3 2
- ADP/ATP translocase 4 2
- AF4/FMR2 family member 1 2
- AF4/FMR2 family member 2 2
- AF4/FMR2 family member 3 2
- AF4/FMR2 family member 4 2
- AFG3-like protein 2 2
- AH receptor-interacting protein 2
- AK1 subfamily 2
- AK2 subfamily 2
- AK3 subfamily 2
- AMP deaminase 1 2
- AMP deaminase 2 2
- AMP deaminase 3 2
- AMSH-like protease 2
- AN1-type zinc finger protein 1 2
- AN1-type zinc finger protein 2A 2
- AN1-type zinc finger protein 2B 2
- AN1-type zinc finger protein 5 2
- AN1-type zinc finger protein 6 2
- AP-1 complex subunit beta-1 2
- AP-1 complex subunit gamma-1 2
- AP-1 complex subunit gamma-like 2 2
- AP-1 complex subunit mu-1 2
- AP-1 complex subunit mu-2 2
- AP-1 complex subunit sigma-1A 2
- AP-1 complex subunit sigma-2 2
- AP-1 complex subunit sigma-3 2
- AP-2 complex subunit alpha-1 2
- AP-2 complex subunit alpha-2 2
- AP-2 complex subunit beta 2
- AP-2 complex subunit mu 2
- AP-2 complex subunit sigma 2
- AP-3 complex subunit beta-1 2
- AP-3 complex subunit beta-2 2
- AP-3 complex subunit delta-1 2
- AP-3 complex subunit mu-1 2
- AP-3 complex subunit mu-2 2
- AP-3 complex subunit sigma-1 2
- AP-3 complex subunit sigma-2 2
- AP-4 complex subunit beta-1 2
- AP-4 complex subunit epsilon-1 2
- AP-4 complex subunit mu-1 2
- AP-4 complex subunit sigma-1 2
- AT-rich interactive domain-containing protein 3A 2
- AT-rich interactive domain-containing protein 3B 2
- AT-rich interactive domain-containing protein 3C 2
- AT-rich interactive domain-containing protein 4A 2
- AT-rich interactive domain-containing protein 4B 2
- AT-rich interactive domain-containing protein 5A 2
- AT-rich interactive domain-containing protein 5B 2
- ATP synthase F(0) complex subunit B1, mitochondrial 2
- ATP synthase mitochondrial F1 complex assembly factor 1 2
- ATP synthase protein 8 2
- ATP synthase subunit a 2
- ATP synthase subunit alpha, mitochondrial 2
- ATP synthase subunit beta, mitochondrial 2
- ATP synthase subunit d, mitochondrial 2
- ATP synthase subunit delta, mitochondrial 2
- ATP synthase subunit e, mitochondrial 2
- ATP synthase subunit epsilon, mitochondrial 2
- ATP synthase subunit f, mitochondrial 2
- ATP synthase subunit g 2, mitochondrial 2
- ATP synthase subunit gamma, mitochondrial 2
- ATP synthase-coupling factor 6, mitochondrial 2
- ATP-binding cassette sub-family A member 1 2
- ATP-binding cassette sub-family A member 10 2
- ATP-binding cassette sub-family A member 12 2
- ATP-binding cassette sub-family A member 13 2
- ATP-binding cassette sub-family A member 2 2
- ATP-binding cassette sub-family A member 3 2
- ATP-binding cassette sub-family A member 5 2
- ATP-binding cassette sub-family A member 6 2
- ATP-binding cassette sub-family A member 7 2
- ATP-binding cassette sub-family A member 8 2
- ATP-binding cassette sub-family A member 9 2
- ATP-binding cassette sub-family B member 10, mitochondrial 2
- ATP-binding cassette sub-family B member 5 2
- ATP-binding cassette sub-family B member 6, mitochondrial 2
- ATP-binding cassette sub-family B member 7, mitochondrial 2
- ATP-binding cassette sub-family B member 8, mitochondrial 2
- ATP-binding cassette sub-family B member 9 2
- ATP-binding cassette sub-family C member 11 2
- ATP-binding cassette sub-family C member 8 2
- ATP-binding cassette sub-family C member 9 2
- ATP-binding cassette sub-family D member 1 2
- ATP-binding cassette sub-family D member 2 2
- ATP-binding cassette sub-family D member 3 2
- ATP-binding cassette sub-family D member 4 2
- ATP-binding cassette sub-family F member 1 2
- ATP-binding cassette sub-family F member 2 2
- ATP-binding cassette sub-family F member 3 2
- ATP-binding cassette sub-family G member 1 2
- ATP-binding cassette sub-family G member 2 2
- ATP-binding cassette sub-family G member 4 2
- ATP-binding cassette sub-family G member 5 2
- ATP-binding cassette sub-family G member 8 2
- ATP-citrate synthase 2
- ATP-dependent 6-phosphofructokinase, muscle type 2
- ATP-dependent 6-phosphofructokinase, platelet type 2
- ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial 2
- ATP-dependent DNA helicase DDX11 2
- ATP-dependent DNA helicase Q1 2
- ATP-dependent DNA helicase Q4 2
- ATP-dependent DNA helicase Q5 2
- ATP-dependent PFK group I subfamily 2
- ATP-dependent RNA helicase A 2
- ATP-dependent RNA helicase DHX29 2
- ATP-dependent RNA helicase DHX36 2
- ATP-dependent RNA helicase DHX8 2
- ATP-dependent RNA helicase DQX1 2
- ATP-dependent RNA helicase TDRD9 2
- ATP-dependent zinc metalloprotease YME1L1 2
- ATP-sensitive inward rectifier potassium channel 1 2
- ATP-sensitive inward rectifier potassium channel 10 2
- ATP-sensitive inward rectifier potassium channel 11 2
- ATP-sensitive inward rectifier potassium channel 12 2
- ATP-sensitive inward rectifier potassium channel 15 2
- ATP:guanido phosphotransferase family 2
- ATPase ASNA1 2
- ATPase WRNIP1 2
- ATPase family AAA domain-containing protein 2 2
- ATPase family AAA domain-containing protein 2B 2
- ATPase family AAA domain-containing protein 3A 2
- ATPase family AAA domain-containing protein 3B 2
- ATPase family AAA domain-containing protein 3C 2
- ATPase inhibitor, mitochondrial 2
- ATR subfamily 2
- Aarf domain-containing protein kinase 4 2
- Abelson tyrosine-protein kinase 2 2
- Abl interactor 1 2
- Abl interactor 2 2
- Acetoacetyl-CoA synthetase 2
- Acetolactate synthase-like protein 2
- Acetyl-CoA acetyltransferase, cytosolic 2
- Acetyl-CoA acetyltransferase, mitochondrial 2
- Acetyl-coenzyme A synthetase 2-like, mitochondrial 2
- Acetyl-coenzyme A synthetase, cytoplasmic 2
- Acetyl-coenzyme A transporter 1 2
- Acetylcholine receptor subunit alpha 2
- Acetylcholine receptor subunit beta 2
- Acetylcholine receptor subunit delta 2
- Acetylcholine receptor subunit epsilon 2
- Acetylcholine receptor subunit gamma 2
- Acetylcholinesterase 2
- Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase 2
- Achaete-scute homolog 1 2
- Achaete-scute homolog 2 2
- Achaete-scute homolog 3 2
- Achaete-scute homolog 4 2
- Achaete-scute homolog 5 2
- Acid ceramidase 2
- Acid sphingomyelinase-like phosphodiesterase 3a 2
- Acid sphingomyelinase-like phosphodiesterase 3b 2
- Acid-sensing ion channel 1 2
- Acid-sensing ion channel 1 (ASIC1) subfamily 2
- Acid-sensing ion channel 2 2
- Acid-sensing ion channel 2 (ASIC2) subfamily 2
- Acid-sensing ion channel 3 2
- Acid-sensing ion channel 3 (ASIC3) subfamily 2
- Acid-sensing ion channel 4 2
- Acid-sensing ion channel 4 (ASIC4) subfamily 2
- Acid-sensing ion channel 5 2
- Acid-sensing ion channel 5 (ASIC5) subfamily 2
- Acidic amino acid decarboxylase GADL1 2
- Acidic leucine-rich nuclear phosphoprotein 32 family member A 2
- Acidic leucine-rich nuclear phosphoprotein 32 family member B 2
- Acidic leucine-rich nuclear phosphoprotein 32 family member C 2
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Target Development Level
Panther Classes
- nucleic acid binding 3072
- transcription factor 1996
- hydrolase 1786
- enzyme modulator 1740
- transferase 1692
- receptor 1680
- signaling molecule 1326
- RNA binding protein 1308
- transporter 1220
- cytoskeletal protein 974
- DNA binding protein 924
- oxidoreductase 816
- kinase 726
- defense/immunity protein 686
- protease inhibitor 614
- zinc finger transcription factor 584
- G-protein modulator 560
- membrane traffic protein 546
- protease 532
- G-protein coupled receptor 520
- protein kinase 506
- serine protease 492
- calcium-binding protein 472
- cysteine protease 456
- ligase 454
- actin family cytoskeletal protein 450
- non-receptor serine/threonine protein kinase 398
- microtubule family cytoskeletal protein 388
- transfer/carrier protein 388
- cell adhesion molecule 386
- ion channel 378
- KRAB box transcription factor 374
- extracellular matrix protein 374
- metalloprotease 370
- dehydrogenase 348
- phosphatase 334
- calmodulin 328
- intracellular calcium-sensing protein 328
- cation transporter 322
- transcription cofactor 322
- G-protein 316
- cytokine receptor 314
- ribosomal protein 314
- mRNA processing factor 298
- nuclease 272
- kinase modulator 264
- glycosyltransferase 250
- growth factor 242
- chromatin/chromatin-binding protein 236
- cytokine 224
- chaperone 220
- immunoglobulin receptor superfamily 218
- mRNA splicing factor 218
- homeodomain transcription factor 216
- reductase 212
- membrane-bound signaling molecule 210
- ubiquitin-protein ligase 198
- cell junction protein 192
- lyase 188
- oxidase 188
- serine protease inhibitor 186
- non-motor actin binding protein 182
- annexin 180
- helix-turn-helix transcription factor 176
- immunoglobulin 176
- acyltransferase 172
- membrane trafficking regulatory protein 166
- structural protein 166
- extracellular matrix glycoprotein 162
- isomerase 162
- small GTPase 160
- winged helix/forkhead transcription factor 156
- basic helix-loop-helix transcription factor 154
- translation factor 154
- guanyl-nucleotide exchange factor 148
- helicase 148
- lipase 146
- methyltransferase 142
- peptide hormone 140
- acetyltransferase 136
- oxygenase 136
- ligand-gated ion channel 134
- non-motor microtubule binding protein 126
- microtubule binding motor protein 124
- protein phosphatase 120
- transmembrane receptor regulatory/adaptor protein 120
- translation initiation factor 114
- histone 112
- kinase activator 106
- nucleotidyltransferase 100
- phosphatase modulator 98
- chemokine 96
- GABA receptor 94
- acetylcholine receptor 94
- ribonucleoprotein 90
- voltage-gated ion channel 90
- RNA helicase 88
- heterotrimeric G-protein 88
- nucleotide kinase 88
- phospholipase 88
- C4 zinc finger nuclear receptor 86
- DNA-directed RNA polymerase 86
- esterase 80
- vesicle coat protein 80
- DNA helicase 74
- amino acid transporter 74
- non-receptor tyrosine protein kinase 74
- ATP synthase 72
- tight junction 72
- ATP-binding cassette (ABC) transporter 68
- deaminase 66
- kinase inhibitor 66
- phosphatase inhibitor 64
- type I cytokine receptor 64
- actin and actin related protein 62
- antibacterial response protein 62
- SNARE protein 60
- basic leucine zipper transcription factor 60
- epimerase/racemase 60
- extracellular matrix structural protein 58
- translation elongation factor 56
- Rel homology transcription factor 54
- actin binding motor protein 54
- nucleotide phosphatase 54
- extracellular matrix linker protein 52
- C2H2 zinc finger transcription factor 50
- aminoacyl-tRNA synthetase 48
- carbohydrate kinase 48
- exoribonuclease 48
- glycosidase 48
- peroxidase 48
- aspartic protease 46
- dehydratase 46
- endoribonuclease 46
- DNA-directed DNA polymerase 44
- protein kinase receptor 44
- sodium channel 44
- tubulin 44
- voltage-gated sodium channel 44
- calcium channel 42
- gap junction 42
- major histocompatibility complex antigen 42
- pyrophosphatase 42
- voltage-gated calcium channel 42
- carbohydrate transporter 40
- damaged DNA-binding protein 40
- HMG box transcription factor 38
- anion channel 38
- storage protein 36
- transaminase 36
- immunoglobulin superfamily cell adhesion molecule 34
- mRNA polyadenylation factor 34
- mitochondrial carrier protein 32
- myelin protein 32
- serine/threonine protein kinase receptor 32
- deacetylase 30
- decarboxylase 30
- intermediate filament 30
- intermediate filament binding protein 30
- neuropeptide 30
- endodeoxyribonuclease 28
- DNA methyltransferase 26
- apolipoprotein 26
- chaperonin 26
- hydratase 26
- TGF-beta receptor 24
- potassium channel 24
- type II cytokine receptor 24
- voltage-gated potassium channel 24
- RNA methyltransferase 22
- complement component 22
- tumor necrosis factor family member 22
- Hsp90 family chaperone 20
- cadherin 20
- phosphodiesterase 20
- phosphorylase 20
- cyclase 18
- P53-like transcription factor 16
- neurotrophic factor 16
- replication origin binding protein 16
- surfactant 16
- viral protein 16
- exodeoxyribonuclease 14
- glucosidase 14
- translation release factor 14
- carbohydrate phosphatase 12
- hydroxylase 12
- DNA glycosylase 10
- MADS box transcription factor 10
- adenylate cyclase 10
- amino acid kinase 10
- galactosidase 10
- guanylate cyclase 10
- ionotropic glutamate receptor 10
- mutase 10
- DNA topoisomerase 8
- interleukin superfamily 8
- transketolase 8
- tyrosine protein kinase receptor 8
- CREB-related transcription factor 6
- Runt transcription factor 6
- TATA-binding transcription factor 6
- DNA ligase 4
- DNA photolyase 4
- Lambda repressor-like transcription factor 4
- amylase 4
- cysteine protease inhibitor 4
- tumor necrosis factor receptor 4
- DNA polymerase processivity factor 2
- aldolase 2
- centromere DNA-binding protein 2
- phosphatase activator 2
- primase 2
- reverse transcriptase 2
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