Tyrphostin RG 14620 - ≥98% , CAS No.136831-49-7

CAS: 136831-49-7 Cat. No.: T337827 Molecular Weight: 275.1 PubChem CID: 5353928
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
(E)-3-(3,5-dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile | MFCD00236445 | (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile | AKOS037645108 | BCP20770 | ZZL6FH3XRC | J-006920 | SCHEMBL7531602 | 4-Phenylbutyric Acid Sodium Salt | AKOS037515517 | H
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
T337827-5mg
3

$34.90

$52.90
Save $18.00 (34.03%)
10mg
T337827-10mg
3

$62.90

$94.90
Save $32.00 (33.72%)
50mg
T337827-50mg
2

$233.90

$350.90
Save $117.00 (33.34%)
100mg
T337827-100mg
2

$397.90

$596.90
Save $199.00 (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Tyrphostin RG 14620 is a non-phenolic tyrphostin analog, which is selective for the EGFR (EGF receptor). The compound inhibits EGF-stimulated HER14 cell proliferation (IC|50|=3 μM) as well as tumor growth in vivo. Tyrphostin RG 14620 contains anti-proliferative effects on renal and bladder carcinoma cell lines. Tyrphostin RG 14620 is an inhibitor of Tyrosine Kinase.

Specifications

Synonyms
(E)-3-(3, 5-dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile | MFCD00236445 | (E)-3-(3, 5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile | AKOS037645108 | BCP20770 | ZZL6FH3XRC | J-006920 | SCHEMBL7531602 | 4-Phenylbutyric Acid Sodium Salt | AKOS037515517 | H
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid504763664
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504763664
Canonical SmilesC1=CC(=CN=C1)C(=CC2=CC(=CC(=C2)Cl)Cl)C#N
IUPAC Name(E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile
InChIKeyTYXIVBJQPBWBHO-QCDXTXTGSA-N
INCHI1S/C14H8Cl2N2/c15-13-5-10(6-14(16)7-13)4-12(8-17)11-2-1-3-18-9-11/h1-7,9H/b12-4-
Isomeric SMILES C1=CC(=CN=C1)/C(=C\C2=CC(=CC(=C2)Cl)Cl)/C#N
WGK Germany 3
PubChem CID 5353928
Molecular Weight 275.1

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassHalobenzenes
Intermediate Tree Nodes Chlorobenzenes
Direct ParentDichlorobenzenes
Alternative Parents Pyridines and derivatives  Aryl chlorides  Heteroaromatic compounds  Nitriles  Azacyclic compounds  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents 1,3-dichlorobenzene - Aryl chloride - Aryl halide - Pyridine - Heteroaromatic compound - Carbonitrile - Nitrile - Azacycle - Organoheterocyclic compound - Organohalogen compound - Organic nitrogen compound - Organochloride - Organonitrogen compound - Cyanide - Hydrocarbon derivative - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
C2626077Certificate of AnalysisApr 11, 2026 T337827
E2216014Certificate of AnalysisFeb 07, 2025 T337827
E2216054Certificate of AnalysisFeb 07, 2025 T337827
E2216057Certificate of AnalysisFeb 07, 2025 T337827
E2216067Certificate of AnalysisFeb 07, 2025 T337827
Chemical and Physical Properties
SolubilitySoluble in DMSO (25 mg/mL), and acetone (25 mg/mL). Insoluble in water.
SensitivityHeat sensitive
Refractive Indexn20D1.66
Boil Point(°C)418.23° C at 760 mmHg
Melt Point(°C)150-151° C
Molecular Weight275.100 g/mol
XLogP33.900
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass274.006 Da
Monoisotopic Mass274.006 Da
Topological Polar Surface Area36.700 Ų
Heavy Atom Count18
Formal Charge0
Complexity348.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.