1,1,2,2-Tetrafluoroethyl 2,2,2-Trifluoroethyl Ether - ≥99% , CAS No.406-78-0

CAS: 406-78-0 Cat. No.: T162708 Molecular Weight: 200.06 EC Number: 609-858-6 PubChem CID: 164596

GRADE & PURITY ≥99%

Synonyms

Ethane,1,1,2,2-tetrafluoro-1-(2,2,2-trifluoroethoxy)- | 1,1,2,2-Tetrafluoro-1-(2,2,2-trifluoroethoxy)ethane | 1,1,2,2,5,5,5-Heptafluoro-3-oxapentane

Storage

Room temperature

Shipped In

Normal

Overview

1,1,2,2-Tetrafluoroethyl 2,2,2-trifluoroethyl ether (TFTFE) is a fluorinated ether that finds extensive use as an electrolyte solvent and diluent in various battery technologies. TFTFE has a low viscosity, low freezing point (-94 °C lit.), low dielectric constant (~6.7), and high electrochemical stability, making it an ideal candidate for use in lithium-ion batteries, lithium-sulfur batteries, and other battery systems. TFTFE is miscible with many polar organic solvents, including carbonates typically used in battery electrolytes. With a minimum purity level of 99% and free from acid impurities, our TFTFE is a reliable and safe solution for critical battery applications. 

Purpose： 

Battery-grade 1,1,2,2-tetrafluoroethyl 2,2,2-trifluoroethyl ether (TFTFE) is a versatile co-solvent and additive for various battery systems. In lithium-metal batteries, TFTFE helps to suppress dendrites without raising the interfacial impedance. It also supports the stable cycling of NMC and lithium metal phosphate cathodes by forming a highly fluorinated interphase, which inhibits oxidation and transition metal dissolution.Because of its stability and low viscosity, TFTFE is commonly added in localized high-concentration electrolytes (LHCE) as a diluent and flame-retardant. In lithium-sulfur batteries, TFTFE plays a key role as both a polysulfide-restraining solvent and a film-forming agent, addressing the polysulfide shuttle (PSS) effect and improving battery performance.Additionally, TFTFE plays a critical role in cell systems with solvate ionic liquids (SIL) as an ionic conduction-enhancing ingredient, particularly for high-rate cycle environments.Our high-purity, anhydrous TFTFE is an ideal battery-grade additive for advanced battery technology.

Specifications

Synonyms

Ethane, 1, 1, 2, 2-tetrafluoro-1-(2, 2, 2-trifluoroethoxy)- | 1, 1, 2, 2-Tetrafluoro-1-(2, 2, 2-trifluoroethoxy)ethane | 1, 1, 2, 2, 5, 5, 5-Heptafluoro-3-oxapentane

Specifications & Purity

≥99%

Storage

Room temperature

Shipped In

Normal

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 488188369
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488188369
• Canonical Smiles: C(C(F)(F)F)OC(C(F)F)(F)F
• IUPAC Name: 1,1,2,2-tetrafluoro-1-(2,2,2-trifluoroethoxy)ethane
• InChIKey: CWIFAKBLLXGZIC-UHFFFAOYSA-N
• INCHI: 1S/C4H3F7O/c5-2(6)4(10,11)12-1-3(7,8)9/h2H,1H2
• Isomeric SMILES: C(C(F)(F)F)OC(C(F)F)(F)F
• PubChem CID: 164596
• UN Number: 3271
• Packing Group: II
• Molecular Weight: 200.06
• Reaxy-Rn: 1762056

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Ethers

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Ethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Dialkyl ethers
• Alternative Parents: Organofluorides Hydrocarbon derivatives Alkyl fluorides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Dialkyl ether - Hydrocarbon derivative - Organofluoride - Organohalogen compound - Alkyl halide - Alkyl fluoride - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Hygroscopic
• Refractive Index: 1.27
• Flash Point(°C): -7 °C
• Boil Point(°C): 56°C
• Molecular Weight: 200.050 g/mol
• XLogP3: 2.800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 200.007 Da
• Monoisotopic Mass: 200.007 Da
• Topological Polar Surface Area: 9.200 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 139.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Yueteng Gao, Wei Li, Boning Ou, Shuhua Zhang, Huwei Wang, Junyang Hu, Feiyu Kang, Dengyun Zhai.  (2023)  A Dilute Fluorinated Phosphate Electrolyte Enables 4.9 V-Class Potassium Ion Full Batteries.  ADVANCED FUNCTIONAL MATERIALS,  33  (47): (2305829).  [PMID:] [10.1002/adfm.202305829]

2. Dichang Guan, Guorong Hu, Zhongdong Peng, Yanbing Cao, Zhanggen Gan, Xudong Zhang, Ke Du.  (2022)  Designing Low-Concentration Propylene Carbonate-based Electrolyte by Manipulating Lithium+-Solvation Structure for Graphite Anode.  Batteries & Supercaps,  5  (10): (e202200257).  [PMID:] [10.1002/batt.202200257]

3. Xiaojuan Chen, Yan Meng, Dan Xiao, Lei Qin.  (2024)  Empowering the Potassium–Sulfur Battery with Commendable Reaction Kinetics and Capacity Output by Localized High-Concentration Electrolytes.  ACS Applied Materials & Interfaces,      [PMID:38710103] [10.1021/acsami.3c19583]

4. Zhanlin Yang, Guolin Hu, Chenyu Wang, Yuansheng Lin, Zhichao Shi, Jianhui Chen, Yongchuan Liu, Jie Shen, Cuilian Wen, Xiangxin Zhang, Yuanqiang Chen, Baisheng Sa.  (2024)  Solvation layer effects on lithium migration in localized High-Concentration Electrolytes: Analyzing the diverse antisolvent Contributions.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39752931] [10.1016/j.jcis.2024.12.217]

5. Ruan Digen, Chen Shunqiang, Guo Jiasen, Wang Dazhuang, Zhu Weiduo, Huang Bing, Li Yuan, Ma Jun, Ma Zhihao, Wang Zihong, Zhu Zhongliang, Cao Ruiguo, Jiao Shuhong, Wu Yiying, Xu Kang, Ren Xiaodi.  (2026)  Molecularly aligned electron channels for ultrafast-charging practical lithium-metal batteries.  Nature Energy,      [PMID:] [10.1038/s41560-025-01961-z]