Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 25 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
| Isomeric SMILES | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC |
|---|---|
| WGK Germany | 3 |
| PubChem CID | 10350317 |
| Molecular Weight | 786.13 |
| Beilstein | 3898070 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Specific Rotation[α] | 5° (C=0.5,CHCl3:MeOH=4:1) |
|---|
| 1. Weihe Zhao, Xiangdong Xu, Shu An, Juehui Wu, Haiyang Wang, Jinmei Luo, Youyuan Yuan, Laisheng Li. (2025) Injectable PROTAC-loaded hydrogel remodels the tumor microenvironment to potentiate radio-immunotherapy. JOURNAL OF CONTROLLED RELEASE, [PMID:40914482] [10.1016/j.jconrel.2025.114200] |
| 2. Yu Wei, Ting He, Qunjie Bi, Huan Yang, Xueyi Hu, Rongrong Jin, Hong Liang, Yongqun Zhu, Rongsheng Tong, Yu Nie. (2023) A cationic lipid with advanced membrane fusion performance for pDNA and mRNA delivery. Journal of Materials Chemistry B, 11 (10): (2095-2107). [PMID:36810919] [10.1039/D2TB02783F] |
| 3. Yan Wang, Shuhui Gao, Kongying Zhu, Lixia Ren, Xiaoyan Yuan. (2022) Integration of Trehalose Lipids with Dissociative Trehalose Enables Cryopreservation of Human RBCs. ACS Biomaterials Science & Engineering, [PMID:36577138] [10.1021/acsbiomaterials.2c01154] |
| 4. He Zhao, Shaojie Ren, Ines Zucker, Yan Bai, Yunkun Wang. (2022) Antibiofouling Polyvinylidene Fluoride Membrane Functionalized by Poly(ionic liquid) Brushes via Atom Transfer Radical Polymerization. ACS ES&T Engineering, [PMID:] [10.1021/acsestengg.1c00440] |
| 5. Dingyuan Liang, Xiangrui Wang, Ying Wang, Zhaomin Dong, Xiaoli Zhao, Wenhong Fan. (2020) The dual effect of natural organic matter on the two-step internalization process of Au@Sio2 in freshwater. WATER RESEARCH, [PMID:32721761] [10.1016/j.watres.2020.116216] |
| 6. Cao Dingding, Shu Xugang, Zhu Dandan, Liang Shengli, Hasan Murtaza, Gong Sheng. (2020) Lipid-coated ZnO nanoparticles synthesis, characterization and cytotoxicity studies in cancer cell. Nano Convergence, 7 (1): (1-18). [PMID:32328852] [10.1186/s40580-020-00224-9] |
| 7. Qihong Zhang, Wei Ren, Alexandr V. Dushkin, Weike Su. (2020) Preparation, characterization, in vitro and in vivo studies of olmesartan medoxomil in a ternary solid dispersion with N-methyl-D-glucamine and hydroxypropyl-β-cyclodextrin. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2020.101546] |
| 8. Ehexige Ehexige, Tsogzolmaa Ganbold, Xiang Yu, Shuqin Han, Huricha Baigude. (2019) Design of Peptidomimetic Functionalized Cholesterol Based Lipid Nanoparticles for Efficient Delivery of Therapeutic Nucleic Acids. MOLECULES, 24 (18): (3413). [PMID:31546908] [10.3390/molecules24183413] |
| 9. Zhixia Liang, Yanbin Yun, Manxiang Wang, Guicheng Liu, Peng Lu, Woochul Yang, Chunli Li. (2019) Performance evaluation of interfacial polymerisation-fabricated aquaporin-based biomimetic membranes in forward osmosis. RSC Advances, 9 (19): (10715-10726). [PMID:35515303] [10.1039/C9RA00787C] |
| 10. Dong Hou, Zhaojian Liu, Xiuhua Xu, Qiao Liu, Xiyu Zhang, Beihua Kong, Jian-Jun Wei, Yaoqin Gong, Changshun Shao. (2018) Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer. Redox Biology, [PMID:29684820] [10.1016/j.redox.2018.03.016] |
| 11. Bangming Wang, Yan Zhao, Mingzhu Zhao, Yuke Han, Hui Zhang, Weiheng Kong, Fengli Qu. (2025) Al-Based Metal–Organic Nanoslice-Coupled Phospholipid Layer Enables Highly Enriched Biological External Vesicles. ANALYTICAL CHEMISTRY, [PMID:39899402] [10.1021/acs.analchem.4c05089] |
| 12. Bo Wang, Jiquan Shen, Xinggao Wang, Ruixing Hou. (2024) Biomimetic nanoparticles for effective Celastrol delivery to targeted treatment of rheumatoid arthritis through the ROS-NF-κB inflammasome axis. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:38503010] [10.1016/j.intimp.2024.111822] |
| 13. Subbulakshmi Ganesan, Vijay J. Upadhye, Nutan Sharma, Arpit Arora, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Samer Hasan Hussein-Al-Ali, Suha Mujahed Abudoleh, Indumathi Thangavelu. (2024) Construction of Sorafenib Tosylate and Etoposide-loaded Liposomes: A Path to Precision Liver Cancer Therapy and its Apoptosis Induction. ChemistrySelect, 9 (48): (e202404117). [PMID:] [10.1002/slct.202404117] |
| 14. Zhiqiang Zhang, Qinglong Wang, Haibo Zhang, Shengchao Wang, Xia Ma, Hui Wang. (2024) Golm1 facilitates the CaO2-DOPC-DSPE200-PEI -CsPbBr3 QDs -induced apoptotic death of hepatocytes through the stimulation of mitochondrial autophagy and mitochondrial reactive oxygen species production through interactions with P53/Beclin-1/Bcl-2. CHEMICO-BIOLOGICAL INTERACTIONS, [PMID:38815669] [10.1016/j.cbi.2024.111076] |
| 15. Qianhua Feng, Xueli Zhang, Xiaowen Zhao, Jia Liu, Qing Wang, Yuqi Yao, Huifang Xiao, Yucui Zhu, Wenwen Zhang, Lei Wang. (2024) Intranasal Delivery of Pure Nanodrug Loaded Liposomes for Alzheimer's Disease Treatment by Efficiently Regulating Microglial Polarization. Small, [PMID:39370581] [10.1002/smll.202405781] |
| 16. Yang Yang, Xin Zhang, Jin Yang, Ziyan Wu, Junpeng Li, Ruilong Song, Chuang Meng, Guoqiang Zhu. (2025) N-(3-Oxododecanoyl)-Homoserine Lactone Induces Intestinal Barrier Damage in Piglets via the Lipid Raft-Mediated Apoptosis Pathway. Veterinary Sciences, 12 (3): (233). [PMID:40266950] [10.3390/vetsci12030233] |
| 17. Zongqi Yang, Xinyu Yu, Bo Huang, Jiahui Li, Xiaohai Yan, Kewei Feng, Rui Cai, Yahong Yuan, Tianli Yue, Qinglin Sheng. (2025) Phospholipid membrane-encapsulated perovskite quantum dots electrospun glass cellulose membrane-based fluorescence and visual two-channel detection of breath ammonia for patients infected with Helicobacter pylori. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113263] |
| 18. Weijun Wang, Wenqing Wang, Yaxin Chen, Mengling Lin, Yan-Ru Chen, Ruijin Zeng, Tenghang He, Zhifa Shen, Zai-Sheng Wu. (2024) Superlarge, Rigidified DNA Tetrahedron with a Y-Shaped Backbone for Organizing Biomolecules Spatially and Maintaining Their Full Bioactivity. ACS Nano, [PMID:38973121] [10.1021/acsnano.3c13189] |
| 19. Feng Tao, Chenkai Sun, Yingze Li, Yingying Wang, Peng Ning, Xiaolei Chen, Donglei Yang, Rui Gao, Yuan Li, Chang Xu, Zihan Guo, Haotian Chen, Xing Fan, Li Peng, Cheng Lv, Xinjian Fan, Chang Chen, Yu Cheng. (2025) Rotational-bouncing nanomotors with atomic edges for lysosomal mechanoporation. Matter, [PMID:] [10.1016/j.matt.2025.102491] |
| 20. Huisong Hao, Yunfei Yi, Yanan Fu, Shengjie Sun, Zhangwen Peng, Jia Tang, Yixuan Fang, Shihao Zhuang, Yaqi Ouyang, Tianqi Wang, Meiying Wu. (2025) A lipid nanosystem establishes precise NO concentration gradient around tumor vessels via endothelial transcytosis, thereby normalizing tumor vasculature and creating an environment beneficial for antitumor immunotherapy. Acta Pharmaceutica Sinica B, [PMID:] [10.1016/j.apsb.2025.11.040] |
| 21. Jinguo Li, Yuhao Zhang, Changyu Shao, Yining Bai, Puxiu Wang, Tianyang Ren. (2025) Utilization of DOX–Fe complex and RSL3 co-loaded liposomes in ferroptosis-enhanced treatment of triple-negative breast cancer. DRUG DELIVERY, [PMID:41340500] [10.1080/10717544.2025.2592412] |
| 22. Wei Liu, Jinwei Zhong, Pui Wo Felix Yeung, Xiahui Xiao, Yuwei Zhu, To Ngai. (2025) Lipid bilayer-mediated spatiotemporal correlation between near-wall confined motion of micro-carriers. Soft Matter, [PMID:41427570] [10.1039/D5SM01211B] |
| 23. Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang. (2026) CRISPR-Cas9-Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real-Time MRI Monitoring. Advanced Science, [PMID:41498761] [10.1002/advs.202519704] |
| 24. Chenyi Xie, Xiaofang Cui, Wei Wei, Peicheng Hong, Lujia You, Ziyao Chen, Lin Li, Lan Wang, Na Wang, Ze-Guang Han. (2026) Lysosome-localized IRTKS condensates promote mTORC1 activity leading to MASLD and HCC. Cell Reports, 45 (2): [PMID:41575860] [10.1016/j.celrep.2025.116893] |
| 25. Qi Wei, Ruoshui Li, Jiaqi Fan, Mengyuan Xu, Pengcheng Yuan, Jiwei Liu, Qian Wang, Youqing Shen, Nigel K. H. Slater, Jianbin Tang. (2026) Amphiphilic Guanidine-based Lipids Enhance mRNA Delivery and Immune Activation. Biomaterials Science, [PMID:41700813] [10.1039/D6BM00068A] |
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