2,4-Dimethylphenol solution - analytical standard, 1000ug/ml in methanol , CAS No.105-67-9

CAS: 105-67-9 Cat. No.: D117387 Molecular Weight: 122.16 Beilstein Registry Number: 636244 EC Number: 203-321-6
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. 1000ug/ml in methanol
Synonyms
2,4-DIMETHYLPHENOL|105-67-9|2,4-Xylenol|m-Xylenol|Phenol, 2,4-dimethyl-|4,6-Dimethylphenol|1-Hydroxy-2,4-dimethylbenzene|4-Hydroxy-1,3-dimethylbenzene|RCRA waste number U101|2,4-Dimethyl phenol|NSC 3829|2,4-Dimethyl-phenol|2,4-Dimethylphenol-d10|DTXSID202
Storage
Room temperature
Shipped In
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Size
Status
Price
Qty
1.2ml
D117387-1.2ml
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Why this grade

analytical standard, 1000ug/ml in methanol Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
2, 4-DIMETHYLPHENOL | 105-67-9 | 2, 4-Xylenol | m-Xylenol | Phenol, 2, 4-dimethyl- | 4, 6-Dimethylphenol | 1-Hydroxy-2, 4-dimethylbenzene | 4-Hydroxy-1, 3-dimethylbenzene | RCRA waste number U101 | 2, 4-Dimethyl phenol | NSC 3829 | 2, 4-Dimethyl-phenol | 2, 4-Dimethylphenol-d10 | DTXSID202
Specifications & Purity
analytical standard, 1000ug/ml in methanol
Storage
Room temperature
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Analytical standard
Names and Identifiers
Canonical SmilesCC1=CC(=C(C=C1)O)C
IUPAC Name2,4-dimethylphenol
InChIKeyKUFFULVDNCHOFZ-UHFFFAOYSA-N
INCHI1S/C8H10O/c1-6-3-4-8(9)7(2)5-6/h3-5,9H,1-2H3
Isomeric SMILES CC1=CC(=C(C=C1)O)C
WGK Germany 3
RTECS ZE5600000
UN Number 2261
Packing Group II
Molecular Weight 122.16
Beilstein 636244
Reaxy-Rn 636244
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=636244&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassXylenes
Intermediate Tree Nodes Not available
Direct ParentXylenols
Alternative Parents m-Xylenes  Para cresols  Ortho cresols  1-hydroxy-2-unsubstituted benzenoids  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Xylenol - M-xylene - P-cresol - O-cresol - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as xylenols. These are aromatic compounds that contain a xylene moiety, which is a monocyclic benzene carrying exactly two methyl groups, and at least one hydroxyl group.
External Descriptors hydroxytoluene
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
K1928068Certificate of AnalysisJun 06, 2023 D117387
Chemical and Physical Properties
SensitivityLight sensitive.
Flash Point(°F)201.2 °F - closed cup
Flash Point(°C)94.0 °C - closed cup
Boil Point(°C)211.5°C
Melt Point(°C)21-23°C
Molecular Weight122.160 g/mol
XLogP32.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass122.073 Da
Monoisotopic Mass122.073 Da
Topological Polar Surface Area20.200 Ų
Heavy Atom Count9
Formal Charge0
Complexity90.600
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Zhentao Li, Zhengzheng Liao, Xiaoru Ding, Jinfang Hu, Zilin Chen.  (2023)  Facile room-temperature synthesis of a spherical mesoporous covalent organic framework for capillary electrochromatography.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38232637] [10.1016/j.chroma.2023.464626]
2. Yi Li, Xinze Wu, Hui Lyu, Huaixia Chen, Xueping Dang.  (2023)  Electrosynthesis of metal coordination cluster Zn5/polyaniline composite coating for headspace solid phase microextraction of nine volatile phenolic compounds in aqueous samples.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.109775]
3. Zhentao Li, Zhengzheng Liao, Jinfang Hu, Zilin Chen.  (2023)  In situ growth of imine-based covalent organic framework as stationary phase for high-efficiency electrochromatographic separation.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36881971] [10.1016/j.chroma.2023.463905]
4. Yuanyuan Fu, Zhentao Li, Qiaoyan Li, Changjun Hu, Yikun Liu, Wenqi Sun, Zilin Chen.  (2021)  In situ room-temperature preparation of a covalent organic framework as stationary phase for high-efficiency capillary electrochromatographic separation.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:34034110] [10.1016/j.chroma.2021.462239]
5. Wenqi Sun, Yikun Liu, Wei Zhou, Zhentao Li, Zilin Chen.  (2021)  In-situ growth of a spherical vinyl-functionalized covalent organic framework as stationary phase for capillary electrochromatography-mass spectrometry analysis.  TALANTA,      [PMID:33934787] [10.1016/j.talanta.2021.122330]
6. Xiaohua Zhang, Weikun Jiang, Hao Ma, Shubin Wu.  (2020)  Relationship between the formation of oligomers and monophenols and lignin structure during pyrolysis process.  FUEL,      [PMID:] [10.1016/j.fuel.2020.118048]
7. Xinhong Yu, Wei Zhou, Zilin Chen.  (2017)  In situ immobilization of layered double hydroxides as stationary phase for capillary electrochromatography.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:29153915] [10.1016/j.chroma.2017.11.021]
8. Xiaohong Yang, Changxia Li, Meiling Qi, Liangti Qu.  (2016)  Graphene-ZIF8 composite material as stationary phase for high-resolution gas chromatographic separations of aliphatic and aromatic isomers.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:27423773] [10.1016/j.chroma.2016.07.029]
9. Yanyan Shan, Zhiqiang Liu, Duxia Cao, Guoqun Liu, Ruifang Guan, Ning Sun, Cong Wang, Kangnan Wang.  (2015)  Coumarinic chalcone derivatives as chemosensors for cyanide anions and copper ions.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2015.06.118]
10. Juan Zhang, Wenpeng Zhang, Tao Bao, Zilin Chen.  (2013)  Mussel-inspired polydopamine-assisted hydroxyapatite as the stationary phase for capillary electrochromatography.  ANALYST,  139  (1): (242-250).  [PMID:24195104] [10.1039/C3AN01668D]
11. Shuchao Wu, Bingcheng Yang, Lingling Xi, Yan Zhu.  (2012)  Determination of phenols with ion chromatography–online electrochemical derivatization based on porous electrode–fluorescence detection.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:22305361] [10.1016/j.chroma.2012.01.025]
12. Ning Zhu, Zhichen Liu, Qiulin Zhang, Man He, Beibei Chen, Bin Hu.  (2025)  3D Printed Clear Resin Stir Bar Sorptive Extraction Coupled with High Performance Liquid Chromatography for Trace Chlorophenols Analysis in Environmental Water Samples.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:39855022] [10.1016/j.chroma.2025.465693]
13. Ju Wei, Bingyu Luo, Jiao Fu, Shunli Zhou, E. Li, Xiaodong Su, Xiaotong Gao, Zhenfu Jia, Xiaojiang Li.  (2025)  The dual-mode fluorescent and colorimetric Ag@R-CDs probe for highly selective detection of Fe³+.  SPECTROSCOPY LETTERS,      [PMID:] [10.1080/00387010.2025.2458157]
14. Wanqian Wei, Yu Shi, Keqing Zhang, Baohui Li.  (2025)  The Preparation of Robust Gully-like Surface of Stainless Steel Fiber-Bonded TFPA–TTA–COF with Nano Pores for Solid-Phase Microextraction of Phenolic Compounds in Water.  Nanomaterials,  15  (5): (354).  [PMID:40072157] [10.3390/nano15050354]
15. Yu Wang, Lingqi Shen, Yuan Yan, Bincheng Gong, Kexian Chen, Guohua Zhu, Zuguang Li.  (2024)  Ultrasound assisted upper critical solution temperature type switchable deep eutectic solvent based liquid-liquid microextraction for the determination of triazole in water.  ANALYTICA CHIMICA ACTA,      [PMID:39266195] [10.1016/j.aca.2024.343172]
16. Jianjun Shu, Pengfei Xie, Danni Lin, Rongfeng Chen, Jiang Wang, Beibei Zhang, Mingming Liu, Hanlan Liu, Fan Liu.  (2013)  Two highly stable and selective solid phase microextraction fibers coated with crown ether functionalized ionic liquids by different sol–gel reaction approaches.  ANALYTICA CHIMICA ACTA,      [PMID:24331051] [10.1016/j.aca.2013.11.006]
17. Liu Haicheng, Rao Chenxuan, Xu Huixuan.  (2025)  Enhancement of Pb(II) adsorption by aged polyethylene terephthalate microplastics in the presence of microalgae: kinetic and mechanistic.  ENVIRONMENTAL GEOCHEMISTRY AND HEALTH,  47  (7): (1-18).  [PMID:40484865] [10.1007/s10653-025-02560-3]
18. Guangming Liao, Yukun Hu, Min Wang, Longyu Tian, Zaijun Lu.  (2025)  Design of Well-Defined Cross-Linked Grids via Alternating Copolymerization of Phenol End-Functionalized Polysulfone Oligomers With Methyl Substituted Benzoxazine Monomers.  JOURNAL OF POLYMER SCIENCE,      [PMID:] [10.1002/pol.20250410]
19. Zhenxin Wang, Yifan Yin, Jiaqi Yang, Jiaye Duan, Xiangkang Zeng, Wuang Ren, Shengjiong Yang, Gen Wang.  (2025)  Electron transfer-driven polymerization of phenolics via CuO-catalyzed peracetic acid for sustainable wastewater remediation.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:41352020] [10.1016/j.jhazmat.2025.140680]
20. Yang Bingnian, Peng Ziqin, Xia Guangping, Ruan Guihua, Huang Yipeng, Tang Ningli.  (2026)  Controllable synthesis of reticulated covalent organic polymers for the rapid extraction of triazine herbicides in vegetables prior to analysis by high-performance liquid chromatography.  MICROCHIMICA ACTA,  193  (3): (150).  [PMID:41663847] [10.1007/s00604-026-07841-x]
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