2-D08 - 10mM in DMSO , CAS No.144707-18-6

CAS: 144707-18-6 Cat. No.: D421647 Molecular Weight: 270.24 EC Number: 808-530-1
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GRADE & PURITY 10mM in DMSO
Synonyms
PD044048 | HY-114166 | SCHEMBL1772778 | D82631 | 2-(2,3,4-Trihydroxyphenyl)-4H-chromen-4-one | BCP18314 | AMY31051 | AS-16368 | 2-(2,3,4-TRIHYDROXYPHENYL)CHROMEN-4-ONE | 2D08;2 D08 | AKOS027322100 | 2',3',4'-trihydroxyflavone | CCG-267148 | s8696 | 2-(2,3
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
D421647-1ml
2

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
PD044048 | HY-114166 | SCHEMBL1772778 | D82631 | 2-(2, 3, 4-Trihydroxyphenyl)-4H-chromen-4-one | BCP18314 | AMY31051 | AS-16368 | 2-(2, 3, 4-TRIHYDROXYPHENYL)CHROMEN-4-ONE | 2D08;2 D08 | AKOS027322100 | 2', 3', 4'-trihydroxyflavone | CCG-267148 | s8696 | 2-(2, 3
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
2-D08 is a small ubiquitin-like modification protein (sumoylation) inhibitor with cell permeability. 2-D08 also inhibited Axl with IC50 of 0.49 nM.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
Canonical SmilesC1=CC=C2C(=C1)C(=O)C=C(O2)C3=C(C(=C(C=C3)O)O)O
IUPAC Name2-(2,3,4-trihydroxyphenyl)chromen-4-one
InChIKeyJJAXTFSPCLZPIW-UHFFFAOYSA-N
INCHI1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19H
Isomeric SMILES C1=CC=C2C(=C1)C(=O)C=C(O2)C3=C(C(=C(C=C3)O)O)O
WGK Germany 3
Molecular Weight 270.24
Reaxy-Rn 26588215
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26588215&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClassFlavonoids
SubclassFlavones
Intermediate Tree Nodes Not available
Direct ParentFlavones
Alternative Parents 4'-hydroxyflavonoids  3'-hydroxyflavonoids  Chromones  5-unsubstituted pyrrogallols  Pyranones and derivatives  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Heteroaromatic compounds  Polyols  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 3'-hydroxyflavonoid - 4'-hydroxyflavonoid - Flavone - Hydroxyflavonoid - Chromone - Benzopyran - 1-benzopyran - 5-unsubstituted pyrrogallol - Benzenetriol - Pyrogallol derivative - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Monocyclic benzene moiety - Benzenoid - Pyran - Heteroaromatic compound - Organoheterocyclic compound - Oxacycle - Polyol - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as flavones. These are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one).
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
APP Tclin Amyloid-beta A4 protein (8510 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Molecular Weight270.240 g/mol
XLogP32.500
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass270.053 Da
Monoisotopic Mass270.053 Da
Topological Polar Surface Area87.000 Ų
Heavy Atom Count20
Formal Charge0
Complexity418.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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