2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate - ≥99% , CAS No.52558-16-4

CAS: 52558-16-4 Cat. No.: D351672 Molecular Weight: 391.19(anhydrous) PubChem CID: 135502779

GRADE & PURITY ≥99%

Synonyms

2'-Deoxyguanosine 5'-monophosphate disodium salt hydrate, >=98% | 2'deoxyguanosine 5'-monophosphate sodium salt hydrate | disodium;[(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate;hydrate | disodium;[(2R,3S,5R)-5-(2-amino-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product Description

2'-Deoxyguanosine 5'-monophosphate sodium salt (dGMP) is converted to dGDP by guanylate kinases. This can be further phosphorylated to form dGTP which supports DNA biosynthesis. Additionally, dGMP can be used to study guanine-based molecules and their physiochemical characteristics.

Product Application

Reactant involved in analysis of self-assembling in solution and nucleation / growth of G-qudruplexes，nucleophilic trapping，reductive alkylation.

Specifications

Synonyms

2'-Deoxyguanosine 5'-monophosphate disodium salt hydrate, >=98% | 2'deoxyguanosine 5'-monophosphate sodium salt hydrate | disodium;[(2R, 3S, 5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate;hydrate | disodium;[(2R, 3S, 5R)-5-(2-amino-

Specifications & Purity

≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])[O-])O.O.[Na+].[Na+]
• IUPAC Name: disodium;[(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate;hydrate
• InChIKey: HQSJCEYJAGVPJG-BIHLCPNHSA-L
• INCHI: 1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1
• Isomeric SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])[O-])O.O.[Na+].[Na+]
• Alternate CAS: 33430-61-4
• PubChem CID: 135502779
• Molecular Weight: 391.19(anhydrous)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleotides
      • Subclass Purine deoxyribonucleotides
        • Level5 Purine deoxyribonucleoside monophosphates
          • Level6 Purine 2'-deoxyribonucleoside monophosphates

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleotides
• Subclass: Purine deoxyribonucleotides
• Intermediate Tree Nodes: Purine deoxyribonucleoside monophosphates
• Direct Parent: Purine 2'-deoxyribonucleoside monophosphates
• Alternative Parents: 6-oxopurines Hypoxanthines Pyrimidones Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Organic oxides Organic sodium salts Organic zwitterions Organopnictogen compounds Primary amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine 2'-deoxyribonucleoside monophosphate - 6-oxopurine - Hypoxanthine - Imidazopyrimidine - Purine - Aminopyrimidine - Pyrimidone - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Tetrahydrofuran - Vinylogous amide - Heteroaromatic compound - Azole - Imidazole - Secondary alcohol - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Oxacycle - Organic salt - Amine - Organooxygen compound - Organonitrogen compound - Alcohol - Organic nitrogen compound - Organic oxide - Primary amine - Organopnictogen compound - Hydrocarbon derivative - Organic oxygen compound - Organic sodium salt - Organic zwitterion - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside monophosphates. These are purine nucleotides with monophosphate group linked to the ribose moiety lacking a hydroxyl group at position 2.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 409.200 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 409.038 Da
• Monoisotopic Mass: 409.038 Da
• Topological Polar Surface Area: 188.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 556.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

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