2-Hydroxypyridine - Moligand™, ≥97% , CAS No.142-08-5

CAS: 142-08-5 Cat. No.: H108693 Molecular Weight: 95.1 Beilstein Registry Number: 105757 EC Number: 205-520-3
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
AKOS000119122 | alpha-Pyridone | Levetiracetam impurity C, European Pharmacopoeia (EP) Reference Standard | lH-2-pyridone | PD144419 | 2-hydroxyl pyridine | 2-Pyridinol | pyridin-2(1H)-one | pyridin2(1h)-one | 2-Hydroxypyridine, 97% | BBL027571 | FT-06126
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
H108693-5g
2
$9.90
10g
H108693-10g
2
$14.90
25g
H108693-25g
2
$19.90
100g
H108693-100g
2
$49.90
250g
H108693-250g
1

$135.90

$203.90
Save $68.00 (33.35%)
500g
H108693-500g
1
$142.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
AKOS000119122 | alpha-Pyridone | Levetiracetam impurity C, European Pharmacopoeia (EP) Reference Standard | lH-2-pyridone | PD144419 | 2-hydroxyl pyridine | 2-Pyridinol | pyridin-2(1H)-one | pyridin2(1h)-one | 2-Hydroxypyridine, 97% | BBL027571 | FT-06126
Specifications & Purity
Moligand™, ≥97%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Purity
≥97%
Names and Identifiers
Pubchem Sid504751756
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751756
Canonical SmilesC1=CC(=O)NC=C1
IUPAC Name1H-pyridin-2-one
InChIKeyUBQKCCHYAOITMY-UHFFFAOYSA-N
INCHI1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)
Isomeric SMILES C1=CC(=O)NC=C1
WGK Germany 3
RTECS UV1144050
Alternate CAS 72762-00-6
Molecular Weight 95.1
Beilstein 105757
Reaxy-Rn 105757
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=105757&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassPyridines and derivatives
SubclassHydropyridines
Intermediate Tree Nodes Not available
Direct ParentPyridinones
Alternative Parents Dihydropyridines  Heteroaromatic compounds  Lactams  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Pyridinone - Dihydropyridine - Heteroaromatic compound - Lactam - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyridinones. These are compounds containing a pyridine ring, which bears a ketone.
External Descriptors a small molecule
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MIA PaCa-2 (5949 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FKBP5 Tchem Peptidyl-prolyl cis-trans isomerase FKBP5 (259 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
C2626091Certificate of AnalysisApr 06, 2026 H108693
F2602082Certificate of AnalysisApr 06, 2026 H108693
G2117262Certificate of AnalysisMay 09, 2025 H108693
G2117263Certificate of AnalysisMay 09, 2025 H108693
G2117270Certificate of AnalysisMay 09, 2025 H108693
G2022041Certificate of AnalysisMay 08, 2024 H108693
L2215642Certificate of AnalysisNov 07, 2022 H108693
L2215566Certificate of AnalysisNov 07, 2022 H108693
L2215563Certificate of AnalysisNov 07, 2022 H108693
L2215557Certificate of AnalysisNov 07, 2022 H108693
L2215523Certificate of AnalysisNov 07, 2022 H108693
J2527169Certificate of AnalysisNov 07, 2022 H108693
G2303606Certificate of AnalysisNov 07, 2022 H108693
D2415428Certificate of AnalysisNov 07, 2022 H108693
K2504133Certificate of AnalysisFeb 16, 2022 H108693
I2519054Certificate of AnalysisFeb 16, 2022 H108693
B2209122Certificate of AnalysisFeb 16, 2022 H108693

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Chemical and Physical Properties
SolubilitySoluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
SensitivityLight sensitive.
Flash Point(°C)210°C
Boil Point(°C)280-281°C
Melt Point(°C)106-107°C
Molecular Weight95.100 g/mol
XLogP3-0.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass95.0371 Da
Monoisotopic Mass95.0371 Da
Topological Polar Surface Area29.100 Ų
Heavy Atom Count7
Formal Charge0
Complexity135.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Zengchao Guo, Jiang Xiao, Weiwei Liu, Yihan Wang, Tengfei Liu, Hui Jiang, Xiaohui Liu, Xuemei Wang.  (2022)  Cationic porphyrin-based nanoparticles assisted with bio-assembly imaging-guided strategy for efficient inactivation of bacteria and promote wound healing.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.141218]
2. Yi Xiao, Haomin Yi, Jingzhi Zhu, Suhua Chen, Guofang Wang, Yilong Liao, Yuanyuan Lei, Liyin Chen, Xingcai Zhang, Fangfu Ye.  (2022)  Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme.  Bioactive Materials,      [PMID:36406255] [10.1016/j.bioactmat.2022.10.002]
3. Yang Dan, Mei Shiliang, Wen Zhuoqi, Wei Xian, Cui Zhongjie, Yang Bobo, Wei Chang, Qiu Yi, Li Min, Li Hui, Zhang Wanlu, Xie Fengxian, Wang Le, Guo Ruiqian.  (2020)  Dual-emission of silicon nanoparticles encapsulated lanthanide-based metal-organic frameworks for ratiometric fluorescence detection of bacterial spores.  MICROCHIMICA ACTA,  187  (12): (1-9).  [PMID:33206253] [10.1007/s00604-020-04643-7]
4. Lei Yuan, Hongshuai Gao, Haiyan Jiang, Shaojuan Zeng, Tao Li, Baozeng Ren, Xiangping Zhang.  (2020)  Experimental and thermodynamic analysis of NH3 absorption in dual-functionalized pyridinium-based ionic liquids.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2020.114601]
5. Cui-Ping Ye, Rui-Nan Wang, Xia Gao, Wen-Ying Li.  (2020)  CO2 Capture Performance of Supported Phosphonium Dual Amine-Functionalized Ionic Liquids@MCM-41.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.0c02547]
6. Li Xin, Lu Chao, Xia Wenquan, Quan Guilan, Huang Ying, Bai Xuequn, Yu Feiyuan, Xu Qian, Qin Wanbing, Liu Daojun, Pan Xin.  (2020)  Poly(L-Glutamic Acid)-Based Brush Copolymers: Fabrication, Self-assembly, and Evaluation as Efficient Nanocarriers for Cationic Protein Drug Delivery.  AAPS PHARMSCITECH,  21  (3): (1-10).  [PMID:31970547] [10.1208/s12249-020-1624-4]
7. Zhao Shuxue, Hu Chunhui, Guo Lizhong, Li Kuiran, Yu Hao.  (2019)  Isolation of a 3-hydroxypyridine degrading bacterium, Agrobacterium sp. DW-1, and its proposed degradation pathway.  AMB Express,  (1): (1-9).  [PMID:31102032] [10.1186/s13568-019-0782-9]
8. Xiao-Yan Luo, Xiao-Yan Chen, Rong-Xing Qiu, Bao-You Pei, Yi Wei, Min Hu, Jin-Qing Lin, Jing-Yang Zhang, Geng-Geng Luo.  (2019)  Enhanced CO2 capture by reducing cation–anion interactions in hydroxyl-pyridine anion-based ionic liquids.  DALTON TRANSACTIONS,  48  (7): (2300-2307).  [PMID:30648718] [10.1039/C8DT04680H]
9. Fei Tong, Xiangyuan Tang, Xin Li, Wenquan Xia, Daojun Liu.  (2016)  The effect of insulin-loaded linear poly(ethylene glycol)-brush-like poly(l-lysine) block copolymer on renal ischemia/reperfusion-induced lung injury through downregulating hypoxia-inducible factor.  International Journal of Nanomedicine,      [PMID:27175073] [10.2147/IJN.S99890]
10. Ying Chen, Lei Tian, Wen Liu, Yi Mei, Qiu-Ju Xing, Yi Mu, Ling-Ling Zheng, Qian Fu, Jian-Ping Zou, Daishe Wu.  (2024)  Controllable Pyridine N-Oxidation–Nucleophilic Dechlorination Process for Enhanced Dechlorination of Chloropyridines: The Cooperation of HCO4– and HO2–.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:38330552] [10.1021/acs.est.3c09878]
11. Zhaoyang Qi, Shiquan Zhong, Huiyun Su, Changshen Ye, Limei Ren, Ting Qiu, Jie Chen.  (2024)  Tuning the cross-linked structure of basic poly(ionic liquid) to develop an efficient catalyst for the conversion of vinyl carbonate to dimethyl carbonate.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2024.05.007]
12. Xiao Zhu, Shuhui Liu, Ruhui Shang, Xin Chen, Yingjie Xu, Yujun Guo, Baoping Ling.  (2024)  Understanding on the structure of novel hydroxypyridine anion-based ionic liquids and their effect on CO2 absorption behavior.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2024.113552]
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