2'-O-Methyluridine - ≥99% , CAS No.2140-76-3

CAS: 2140-76-3 Cat. No.: M119523 Molecular Weight: 258.23 EC Number: 966-056-1
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
2 inverted exclamation marka-O-Methyluridine | 2'-o-Methyluridine, AldrichCPR | UNII-399VZB6TMB | AKOS015919383 | 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione | O2'-Methyluridine | Uridine, 2'-O
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
200mg
M119523-200mg
3
$9.90
1g
M119523-1g
3
$10.90
5g
M119523-5g
2
$13.90
10g
M119523-10g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$24.90
25g
M119523-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$47.90
100g
M119523-100g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$156.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
2 inverted exclamation marka-O-Methyluridine | 2'-o-Methyluridine, AldrichCPR | UNII-399VZB6TMB | AKOS015919383 | 1-[(2R, 3R, 4R, 5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione | O2'-Methyluridine | Uridine, 2'-O
Specifications & Purity
≥99%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Pubchem Sid504756510
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504756510
Canonical SmilesCOC1C(C(OC1N2C=CC(=O)NC2=O)CO)O
IUPAC Name1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChIKeySXUXMRMBWZCMEN-ZOQUXTDFSA-N
INCHI1S/C10H14N2O6/c1-17-8-7(15)5(4-13)18-9(8)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
Isomeric SMILES CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O
Molecular Weight 258.23
Reaxy-Rn 39610875
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=39610875&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassNucleosides, nucleotides, and analogues
ClassPyrimidine nucleosides
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPyrimidine nucleosides
Alternative Parents Glycosylamines  Pyrimidones  Hydroxypyrimidines  Monosaccharides  Hydropyrimidines  Tetrahydrofurans  Heteroaromatic compounds  Secondary alcohols  Azacyclic compounds  Oxacyclic compounds  Dialkyl ethers  Hydrocarbon derivatives  Organic oxides  Organonitrogen compounds  Organopnictogen compounds  Primary alcohols  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Pyrimidine nucleoside - Glycosyl compound - N-glycosyl compound - Pyrimidone - Hydroxypyrimidine - Hydropyrimidine - Monosaccharide - Pyrimidine - Tetrahydrofuran - Heteroaromatic compound - Secondary alcohol - Azacycle - Organoheterocyclic compound - Dialkyl ether - Oxacycle - Ether - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Alcohol - Organic oxygen compound - Organic nitrogen compound - Primary alcohol - Organopnictogen compound - Organic oxide - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyrimidine nucleosides. These are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety.
External Descriptors methyluridine
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
A1305017Certificate of AnalysisOct 12, 2024 M119523
L22071132Certificate of AnalysisNov 14, 2022 M119523
L22071133Certificate of AnalysisNov 14, 2022 M119523
K1823125Certificate of AnalysisSep 16, 2022 M119523
Chemical and Physical Properties
SolubilitySoluble in water
SensitivityHeat Sensitive
Specific Rotation[α]+40.0 to +44.0°(C=2、H2O)
Melt Point(°C)161°C
Molecular Weight258.230 g/mol
XLogP3-1.400
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass258.085 Da
Monoisotopic Mass258.085 Da
Topological Polar Surface Area108.000 Ų
Heavy Atom Count18
Formal Charge0
Complexity385.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Sirui Zhu, Yuanyuan Li, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu.  (2023)  The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis.  DEVELOPMENTAL CELL,      [PMID:37977150] [10.1016/j.devcel.2023.10.014]
2. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin.  (2023)  A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L..  Genes,  14  (6): (1287).  [PMID:37372467] [10.3390/genes14061287]
3. Deng Dehai, Qin Yichao, Lin Xiuying, Chu Meng, Lv Daizhu, Lin Huan.  (2025)  Unveiling transfer RNA modifications of oil palm and their dynamic changes during fruit ripening.  BMC PLANT BIOLOGY,  25  (1): (1-17).  [PMID:40155815] [10.1186/s12870-025-06426-9]
Solution Calculators
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