≥98%, R, S mixture for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Canonical Smiles | CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C |
|---|---|
| IUPAC Name | (1S,2S,4R,6R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
| InChIKey | VOVIALXJUBGFJZ-VXKMTNQYSA-N |
| INCHI | 1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21+,22+,23-,24-,25+/m0/s1 |
| Isomeric SMILES | CCC[C@@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C |
| Molecular Weight | 430.53 |
| Reaxy-Rn | 25086959 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25086959&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Steroids and steroid derivatives |
| Subclass | Hydroxysteroids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 21-hydroxysteroids |
| Alternative Parents | Gluco/mineralocorticoids, progestogins and derivatives 20-oxosteroids 3-oxo delta-1,4-steroids 11-beta-hydroxysteroids Delta-1,4-steroids Alpha-hydroxy ketones 1,3-dioxolanes Secondary alcohols Cyclic ketones Cyclic alcohols and derivatives Oxacyclic compounds Acetals Primary alcohols Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Progestogin-skeleton - 21-hydroxysteroid - Pregnane-skeleton - 20-oxosteroid - 3-oxo-delta-1,4-steroid - 3-oxosteroid - 11-hydroxysteroid - 11-beta-hydroxysteroid - Oxosteroid - Delta-1,4-steroid - Meta-dioxolane - Alpha-hydroxy ketone - Cyclic alcohol - Ketone - Cyclic ketone - Secondary alcohol - Organoheterocyclic compound - Oxacycle - Acetal - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Alcohol - Primary alcohol - Aliphatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone. |
| External Descriptors | Not available |
| Molecular Weight | 430.500 g/mol |
|---|---|
| XLogP3 | 2.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 430.236 Da |
| Monoisotopic Mass | 430.236 Da |
| Topological Polar Surface Area | 93.100 Ų |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 862.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jinniu Zhang, Yun Huang, Wenhao Shen, Yixing Zeng, Yingjing Miao, Nianping Feng, Tianyuan Ci. (2025) Effects of Surface Charge of Inhaled Liposomes on Drug Efficacy and Biocompatibility. Pharmaceutics, 17 (3): (329). [PMID:40142994] [10.3390/pharmaceutics17030329] |
| 2. Xu Zuo, Yinuo Gu, Xiaoping Guo, Wenxue Zheng, Haoyu Zheng, Yiming An, Caina Xu, Fang Wang. (2024) Preparation of Budesonide-Loaded Liposomal Nanoparticles for Pulmonary Delivery and Their Therapeutic Effect in OVA-Induced Asthma in Mice. International Journal of Nanomedicine, [PMID:38283200] [10.2147/IJN.S441345] |
| 3. Mengqi Tong, Xi Kuang, Qiaoying Jiang, Gaoxiang Li, Lulu Jin, Yihao Ye, Yi Pan, Yang Zhu, Xiaozhou Mou, Zhengwei Mao, Yueliang Zheng. (2025) Spore-inspired inhalation drug delivery system for asthma therapy. Bioactive Materials, [PMID:40809511] [10.1016/j.bioactmat.2025.07.045] |
| 4. Lin Cao, Jing Peng, Dengyi Duan, Haoran Cai, Qi Cao, Wenyi Zhang, Jinfeng Han, Kangkang Liu, Jianmin Li, Yuanjie Niu, Xuening Zhang, Yang Zhao, Gang Han. (2025) Colon Enzyme-Activated Prebiotic Nanomedicine for Targeted Therapy of Inflammatory Bowel Disease. Small Methods, [PMID:40509675] [10.1002/smtd.202401408] |
| 5. Zhiyue Cai, Zhouyi Liao, Haowen Zhang, Jie Liu. (2025) Dual-targeting nanoparticles based on hyaluronic acid and cystatin for enhanced glomerular uptake of budesonide in nephritis therapy. MATERIALS TECHNOLOGY, [PMID:] [10.1080/10667857.2025.2606170] |
| 6. Zhang Rui Xue, Lu Weijia, Yan Xu, Deng Xudong, Wan Runrun, Song Zhejun, Liang Jiayan, Wang Xue-Ting, Cao Tingting, Chen Yan, Tam Paul K. H.. (2026) Rectal nanoparticulate-hydrogel delivering budesonide to reduce enterohepatic drug metabolism and clearance. Drug Delivery and Translational Research, [PMID:] [10.1007/s13346-026-02095-9] |
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