3,3'-Thiodipropionic acid - ≥98% , CAS No.111-17-1

CAS: 111-17-1 Cat. No.: T106635 Molecular Weight: 178.21 Beilstein Registry Number: 1210299 EC Number: 203-841-3 PubChem CID: 8096
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
DTXCID6024200 | THIODIPROPIONIC ACID [INCI] | .beta.,.beta.'-Thiodipropionic acid | 3-(2-carboxyethylsulfanyl)propanoic acid | Kyselina .beta.,.beta.'-thiodipropionova | NSC 8166 | Q2823309 | 3,3-Thiodipropionicacid | 3,3'-Thiobispropanoic acid | 3,3'-Thi
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
T106635-25g
2

$12.90

$19.90
Save $7.00 (35.18%)
100g
T106635-100g
10

$20.90

$31.90
Save $11.00 (34.48%)
500g
T106635-500g
3

$25.90

$38.90
Save $13.00 (33.42%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Application:

3,3′-Thiodipropionic acid is an organic disulfide that can be used as a ligand for the synthesis of cadminum and zinc coordination polymers with luminescent properties.

Specifications

Synonyms
DTXCID6024200 | THIODIPROPIONIC ACID [INCI] | .beta., .beta.'-Thiodipropionic acid | 3-(2-carboxyethylsulfanyl)propanoic acid | Kyselina .beta., .beta.'-thiodipropionova | NSC 8166 | Q2823309 | 3, 3-Thiodipropionicacid | 3, 3'-Thiobispropanoic acid | 3, 3'-Thi
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488180690
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180690
Canonical SmilesC(CSCCC(=O)O)C(=O)O
IUPAC Name3-(2-carboxyethylsulfanyl)propanoic acid
InChIKeyODJQKYXPKWQWNK-UHFFFAOYSA-N
INCHI1S/C6H10O4S/c7-5(8)1-3-11-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)
Isomeric SMILES C(CSCCC(=O)O)C(=O)O
WGK Germany 2
RTECS UF7990000
PubChem CID 8096
Molecular Weight 178.21
Beilstein 1210299

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassDicarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentDicarboxylic acids and derivatives
Alternative Parents Fatty acids and conjugates  Sulfenyl compounds  Dialkylthioethers  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Fatty acid - Dicarboxylic acid or derivatives - Dialkylthioether - Sulfenyl compound - Thioether - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

61 results found

Lot NumberCertificate TypeDateItem
I2423686Certificate of AnalysisSep 12, 2024 T106635
I2405338Certificate of AnalysisAug 12, 2024 T106635
H2420146Certificate of AnalysisAug 12, 2024 T106635
H2401108Certificate of AnalysisJul 26, 2024 T106635
G2419389Certificate of AnalysisJun 07, 2024 T106635
F2417048Certificate of AnalysisJun 07, 2024 T106635
F2414418Certificate of AnalysisMay 31, 2024 T106635
F2414417Certificate of AnalysisMay 31, 2024 T106635
E2431463Certificate of AnalysisMay 20, 2024 T106635
E2431524Certificate of AnalysisMay 20, 2024 T106635
G2405072Certificate of AnalysisMay 06, 2024 T106635
E2413462Certificate of AnalysisMay 06, 2024 T106635
G2425073Certificate of AnalysisMay 06, 2024 T106635
E2413508Certificate of AnalysisApr 28, 2024 T106635
E2413507Certificate of AnalysisApr 28, 2024 T106635
E2413501Certificate of AnalysisApr 28, 2024 T106635
E2413500Certificate of AnalysisApr 28, 2024 T106635
E2413498Certificate of AnalysisApr 28, 2024 T106635
E2413499Certificate of AnalysisApr 28, 2024 T106635
E2408330Certificate of AnalysisApr 28, 2024 T106635
E2408283Certificate of AnalysisApr 28, 2024 T106635
D2430144Certificate of AnalysisApr 28, 2024 T106635
F2412369Certificate of AnalysisApr 26, 2024 T106635
D2410313Certificate of AnalysisApr 01, 2024 T106635
D2410312Certificate of AnalysisApr 01, 2024 T106635
D2410311Certificate of AnalysisApr 01, 2024 T106635
D2410310Certificate of AnalysisApr 01, 2024 T106635
D2410309Certificate of AnalysisApr 01, 2024 T106635
H2508006Certificate of AnalysisMar 18, 2024 T106635
C2419386Certificate of AnalysisMar 18, 2024 T106635
C2419384Certificate of AnalysisMar 18, 2024 T106635
C2419383Certificate of AnalysisMar 18, 2024 T106635
C2419382Certificate of AnalysisMar 18, 2024 T106635
H2508007Certificate of AnalysisDec 25, 2023 T106635
L2327246Certificate of AnalysisDec 25, 2023 T106635
L2327245Certificate of AnalysisDec 25, 2023 T106635
L2315021Certificate of AnalysisDec 12, 2023 T106635
L2315020Certificate of AnalysisDec 12, 2023 T106635
L2315019Certificate of AnalysisDec 12, 2023 T106635
L2315018Certificate of AnalysisDec 12, 2023 T106635
L2318523Certificate of AnalysisDec 12, 2023 T106635
K2320175Certificate of AnalysisNov 15, 2023 T106635
K2320174Certificate of AnalysisNov 15, 2023 T106635
H2315588Certificate of AnalysisAug 07, 2023 T106635
H2315589Certificate of AnalysisAug 07, 2023 T106635
H2315590Certificate of AnalysisAug 07, 2023 T106635
H2315679Certificate of AnalysisAug 07, 2023 T106635
H2315680Certificate of AnalysisAug 07, 2023 T106635
H2312041Certificate of AnalysisJul 29, 2023 T106635
H2312067Certificate of AnalysisJul 29, 2023 T106635
E2625122Certificate of AnalysisJul 29, 2023 T106635
G2303652Certificate of AnalysisJul 03, 2023 T106635
G2303649Certificate of AnalysisJul 03, 2023 T106635
G2303650Certificate of AnalysisJul 03, 2023 T106635
G2303651Certificate of AnalysisJul 03, 2023 T106635
G2303653Certificate of AnalysisJul 03, 2023 T106635
C2201040Certificate of AnalysisMar 12, 2022 T106635
C2219610Certificate of AnalysisFeb 23, 2022 T106635
C2219639Certificate of AnalysisFeb 23, 2022 T106635
E2304285Certificate of AnalysisFeb 23, 2022 T106635
C2219599Certificate of AnalysisFeb 23, 2022 T106635

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Chemical and Physical Properties
SolubilitySoluble in acetone, ethanol. Slightly soluble in water.
Flash Point(°C)128℃
Melt Point(°C)130-133°C
Molecular Weight178.210 g/mol
XLogP3-0.100
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass178.03 Da
Monoisotopic Mass178.03 Da
Topological Polar Surface Area99.900 Ų
Heavy Atom Count11
Formal Charge0
Complexity130.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Feng Qing, Yang Jing, Dou Mingyuan, Zou Shuai, Wei Lixia, Huang Fuchuan.  (2023)  Modified Ti3C2TX MXene/GO Nanohybrids: An Efficient Lubricating Additive for Tribological Applications.  ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING,      [PMID:] [10.1007/s13369-023-08303-9]
2. Hui Fu, Kai Wang, Hao Wu, Chris R. Bowen, Zhi Fang, Zebin Yan, Shuheng Jiang, Deliu Ou, Yang Yang, Jinju Zheng, Weiyou Yang.  (2023)  Enhanced Hygrothermal Stability of In-Situ-Grown MAPbBr3 Nanocrystals in Polymer with Suppressed Desorption of Ligands.  INORGANIC CHEMISTRY,      [PMID:37545093] [10.1021/acs.inorgchem.3c01834]
3. Sun Xin, Cheng Zhengzai, Djouonkep Lesly Dasilva Wandji, Lan Chupeng, Jia Ruyan, Zeng Sheng, Cheng Junpeng, Tang Ran, Li Yi, Yuan Beibei, Gauthier Mario.  (2023)  Synthesis and Characterization of Novel Hydrolytically Degradable Polyesters.  JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION,  38  (2): (467-473).  [PMID:] [10.1007/s11595-023-2720-6]
4. Hui Wang, Weili Wang, Qianqian Xie, Di Wu, Jiayu Cao, Huilin Chen, Meng Gao, Huizhen Zheng, Xi Liu, Jie Jiang, Wenjie Li, Xiaoming Cai, Sergey V. Gudkov, Ruibin Li.  (2023)  Using Chicken Embryos to Identify the Key Determinants of Nanoparticles for the Crossing of Air–Blood Barriers.  ANALYTICAL CHEMISTRY,      [PMID:37005435] [10.1021/acs.analchem.3c00034]
5. Qing Feng, Fukang Deng, Kangchun Li, Mingyuan Dou, Shuai Zou, Fuchuan Huang.  (2021)  Enhancing the tribological performance of Ti3C2 MXene modified with tetradecylphosphonic acid.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2021.126903]
6. Yinxian Yang, Bingjun Sun, Shiyi Zuo, Ximu Li, Shuang Zhou, Lingxiao Li, Cong Luo, Hongzhuo Liu, Maosheng Cheng, Yongjun Wang, Shujun Wang, Zhonggui He, Jin Sun.  (2020)  Trisulfide bond–mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity.  Science Advances,  (45):   [PMID:33148644] [10.1126/sciadv.abc1725]
7. Wei Wei, Cong Luo, Jincheng Yang, Bingjun Sun, Dongyang Zhao, Yan Liu, Yingli Wang, Wenqian Yang, Qiming Kan, Jin Sun, Zhonggui He.  (2018)  Precisely albumin-hitchhiking tumor cell-activated reduction/oxidation-responsive docetaxel prodrugs for the hyperselective treatment of breast cancer.  JOURNAL OF CONTROLLED RELEASE,      [PMID:30017721] [10.1016/j.jconrel.2018.07.010]
8. Tang Shilin, He Chuansheng, Li Dong, Cai Wenhao, Fan Louzhen, Li Yunchao.  (2018)  Precursor reactivity differentiation for single-step preparation of Ag2Se@Ag2S core–shell nanocrystals with distinct absorption and emission properties enabling sensitive near-infrared photodetection.  JOURNAL OF MATERIALS SCIENCE,  53  (16): (11355-11366).  [PMID:] [10.1007/s10853-018-2465-3]
9. Lei Chen, Jiabao Liu, Chunxiang Gui, Ke mei, Xiaoshuang Dai, Yang Song, Daobing Jiang, Lian Deng, Junda Liu, Neng Qiu.  (2025)  Self-assembled ROS -responsive podollyllotoxin twin drug nanoparticles for enhanced anticancer therapy.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2025.106650]
10. Defan Zeng, Wenfeng Peng, Yupan Li, Fuquan Zhang, Xiaoxue Liao, Lusheng Liao.  (2025)  Effect of High-Efficiency Antioxidant on Storage Stability of Constant-Viscosity Natural Rubber.  POLYMER ENGINEERING AND SCIENCE,      [PMID:] [10.1002/pen.70220]
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