≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
3,4-Difluoroaniline (3,4-DFA) was degraded, under aerobic conditions, by Pseudomonas fluorescens.
3,4-Difluoroaniline was used to prepare thiourea-containing sorafenib analogs or fluorinated 2-(4-aminophenyl)benzothiazoles as potential antitumor agents.
| Pubchem Sid | 504755183 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504755183 |
| Canonical Smiles | C1=CC(=C(C=C1N)F)F |
| IUPAC Name | 3,4-difluoroaniline |
| InChIKey | AXNUZKSSQHTNPZ-UHFFFAOYSA-N |
| INCHI | 1S/C6H5F2N/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2 |
| Isomeric SMILES | C1=CC(=C(C=C1N)F)F |
| RTECS | CX9871900 |
| UN Number | 2941 |
| Packing Group | III |
| Molecular Weight | 129.11 |
| Reaxy-Rn | 971235 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=971235&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Aniline and substituted anilines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aniline and substituted anilines |
| Alternative Parents | Fluorobenzenes Aryl fluorides Primary amines Organopnictogen compounds Organofluorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Aniline or substituted anilines - Halobenzene - Fluorobenzene - Aryl halide - Aryl fluoride - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E1828015 | Certificate of Analysis | Dec 16, 2025 | D155253 |
| B2215591 | Certificate of Analysis | Nov 13, 2025 | D155253 |
| B2215601 | Certificate of Analysis | Nov 13, 2025 | D155253 |
| B2215602 | Certificate of Analysis | Nov 13, 2025 | D155253 |
| B2215603 | Certificate of Analysis | Nov 13, 2025 | D155253 |
| K2004065 | Certificate of Analysis | Aug 20, 2024 | D155253 |
| K2004066 | Certificate of Analysis | Aug 20, 2024 | D155253 |
| F2329218 | Certificate of Analysis | Jan 11, 2022 | D155253 |
| F2329219 | Certificate of Analysis | Jan 11, 2022 | D155253 |
| F2329224 | Certificate of Analysis | Jan 11, 2022 | D155253 |
| Sensitivity | Air sensitive;Light sensitive |
|---|---|
| Refractive Index | 1.513 |
| Boil Point(°C) | 77 °C/7 mmHg |
| Melt Point(°C) | 22 °C |
| Molecular Weight | 129.110 g/mol |
| XLogP3 | 1.600 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 129.039 Da |
| Monoisotopic Mass | 129.039 Da |
| Topological Polar Surface Area | 26.000 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 97.100 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Tu Hong, Tian Bihong, Chen Shunshun, Xu Jingyi, Yang Jianrong, Zhao Zhichao, Chen Shunhong, Wu Jian. (2025) Enhancing photocatalytic efficiency through surface modification to manipulate internal electron-hole distribution. npj Clean Water, 8 (1): (1-10). [PMID:] [10.1038/s41545-025-00480-4] |
| 2. Meiqiong Yu, Ahai Shahe, Jie Zou, Yixin Hu, Yuxuan Yang, Shucui Han, Jinbei Yang. (2025) Density, dynamic viscosity, and saturated vapor pressure of four difluoroaniline isomers at different temperatures and atmospheric pressure. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2025.129219] |
