4-[1-ethyl-7-(piperazin-1-ylmethyl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine - Moligand™ , Inhibitor of ribosomal protein S6 kinase A5, CAS No.E608979, Inhibitor of ribosomal protein S6 kinase A5

CAS: E608979 Cat. No.: E608979 PubChem CID: 44397277

GRADE & PURITY Moligand™

Synonyms

compound 24

Storage

Room temperature

Specifications

Synonyms

compound 24

Specifications & Purity

Moligand™

Storage

Room temperature

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Inhibitor of ribosomal protein S6 kinase A5

Names and Identifiers

• Canonical Smiles: CCn1c(nc2c1c(CN1CCNCC1)cnc2)c1nonc1N
• IUPAC Name: 4-[1-ethyl-7-(piperazin-1-ylmethyl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
• InChIKey: OXZLPOLYTISTQY-UHFFFAOYSA-N
• INCHI: 1S/C15H20N8O/c1-2-23-13-10(9-22-5-3-17-4-6-22)7-18-8-11(13)19-15(23)12-14(16)21-24-20-12/h7-8,17H,2-6,9H2,1H3,(H2,16,21)
• Isomeric SMILES: CCN1C2=C(C=NC=C2CN3CCNCC3)N=C1C4=NON=C4N
• PubChem CID: 44397277

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Imidazopyridines
      • Subclass Imidazo-[4,5-c]pyridines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Imidazopyridines
• Subclass: Imidazo-[4,5-c]pyridines
• Intermediate Tree Nodes: Not available
• Direct Parent: Imidazo-[4,5-c]pyridines
• Alternative Parents: N-alkylpiperazines Aralkylamines Pyridines and derivatives N-substituted imidazoles Imidolactams Heteroaromatic compounds Furazans Trialkylamines Oxacyclic compounds Dialkylamines Azacyclic compounds Primary amines Organic oxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Imidazo-[4,5-c]pyridine - N-alkylpiperazine - Aralkylamine - 1,4-diazinane - N-substituted imidazole - Piperazine - Pyridine - Imidolactam - Azole - Furazan - Imidazole - Oxadiazole - Heteroaromatic compound - Tertiary amine - Tertiary aliphatic amine - Secondary aliphatic amine - Secondary amine - Oxacycle - Azacycle - Organic nitrogen compound - Primary amine - Hydrocarbon derivative - Organonitrogen compound - Organic oxygen compound - Amine - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as imidazo-[4,5-c]pyridines. These are organic heterocyclic compounds containing an imidazo-[4,5-c]pyridine ring system. Imidazo-[4,5-c]pyridine consists of an imidazole ring fused to a pyridine, so that the three ring nitrogen atoms are at the 1-, 2-, and 5-position, respectively.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

RPS6KA5 Tchem Ribosomal protein S6 kinase alpha-5 (2 Activities)

Discover Target: RPS6KA5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RPS6KA5 Tchem Ribosomal protein S6 kinase alpha 5 (3355 Activities)

Discover Target: RPS6KA5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action